scholarly journals Faculty Opinions recommendation of Feasibility and treatment effect of cognitive behavioral therapy for insomnia in individuals with multiple sclerosis: A pilot randomized controlled trial.

2022 ◽  
Author(s):  
Michael Perlis
Keyword(s):  
Multiple Sclerosis ◽  
Randomized Controlled Trial ◽  
Cognitive Behavioral Therapy ◽  
Treatment Effect ◽  
Behavioral Therapy ◽  
Controlled Trial ◽  
Cognitive Behavioral ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals A Pilot Randomized Controlled Trial of Brief Cognitive‐Behavioral Therapy for Anxiety in Patients with Terminal Cancer

2012 ◽  
Vol 17 (10) ◽  
pp. 1337-1345 ◽  
Author(s):  
Joseph A. Greer ◽  
Lara Traeger ◽  
Heather Bemis ◽  
Jessica Solis ◽  
Ellen S. Hendriksen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Controlled Trial ◽  
Cognitive Behavioral ◽  
Terminal Cancer ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals Cognitive behavioral therapy positively affects fatigue in patients with multiple sclerosis: Results of a randomized controlled trial

2017 ◽  
Vol 23 (11) ◽  
pp. 1542-1553 ◽  
Author(s):  
Lizanne E van den Akker ◽  
Heleen Beckerman ◽  
Emma H Collette ◽  
Jos WR Twisk ◽  
Gijs Bleijenberg ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Randomized Controlled Trial ◽  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Controlled Trial ◽  
Cognitive Behavioral ◽  
Control Treatment ◽  
Post Intervention ◽  
Randomized Controlled ◽  
Societal Participation

Background: Fatigue is a common symptom in multiple sclerosis (MS) and often restricts societal participation. Cognitive behavioral therapy (CBT) may alleviate MS-related fatigue, but evidence in literature is inconclusive. Objective: To evaluate the effectiveness of CBT to improve MS-related fatigue and participation. Methods: In a multi-center, assessor-masked, randomized controlled trial, participants with severe MS-related fatigue were assigned to CBT or control treatment. CBT consisted of 12 individual sessions with a psychologist trained in CBT, the control treatment consisted of three consultations with a MS nurse, both delivered over 16 weeks. Assessments were at baseline, 8, 16 (i.e. post-intervention), 26, and 52 weeks post-baseline. Primary outcomes were the Checklist Individual Strength-fatigue subscale (CIS20r fatigue) and the Impact on Participation and Autonomy questionnaire (IPA). Data were analyzed according to the intention-to-treat principle, using mixed-model analysis. Results: Between 2011 and 2014, 91 patients were randomized (CBT: n = 44; control: n = 47). Between-group analysis showed a positive post-intervention effect for CBT on CIS20r fatigue (T16: −6.7 (95% confidence interval (CI) = −10.7; −2.7) points) that diminished during follow-up (T52: 0.5 (95% CI = −3.6; 4.4)). No clinically relevant effects were found on societal participation. Conclusion: Severe MS-related fatigue can be reduced effectively with CBT in the short term. More research is needed on how to maintain this effect over the long term.

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