Faculty Opinions recommendation of A study of intrauterine infusion of human chorionic gonadotropin (hCG) before frozen-thawed embryo transfer after two or more implantation failures.

2020 ◽  
Author(s):  
Steven L Young
Keyword(s):  
Embryo Transfer ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Frozen Thawed Embryo Transfer ◽  
Thawed Embryo Transfer

scholarly journals Effect of intrauterine injection of human chorionic gonadotropin before frozen–thawed embryo transfer on pregnancy outcomes in women with endometriosis

2019 ◽  
Vol 47 (7) ◽  
pp. 2873-2880 ◽  
Author(s):  
Zhihui Xu ◽  
Wenming Chen ◽  
Chune Chen ◽  
Yikang Xiao ◽  
Xia Chen
Keyword(s):  
Birth Weight ◽  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Clinical Pregnancy ◽  
Control Group ◽  
Neonatal Birth Weight ◽  
Frozen Thawed Embryo Transfer ◽  
Thawed Embryo Transfer

Objective To investigate the effect of human chorionic gonadotropin (hCG) intrauterine injection before frozen–thawed embryo transfer (FET) in women with endometriosis. Methods This retrospective cohort study included 45 women with endometriosis who underwent hCG intrauterine injection before FET; each woman was matched with three patients with endometriosis who did not receive hCG intrauterine injection (controls). Data on pregnancy and prenatal outcomes were extracted from medical records and compared. Results Patients in the hCG intrauterine injection group had significantly higher rates of pregnancy and clinical pregnancy (64.4% and 57.8%, respectively) than controls (47.4% and 39.3%, respectively). Neonatal birth weight for both singletons and twins was significantly higher in the hCG group (3486 ± 458 g and 2710 ± 437 g, respectively) than in the control group (3195 ± 401 g and 2419 ± 370 g, respectively). Conclusion Pregnancy rate, clinical pregnancy rate, and birth weight were improved in women with endometriosis who underwent intrauterine hCG injection compared with those who did not receive hCG before FET.

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