scholarly journals Prevalence of Recurrent Herniation Following Percutaneous Endoscopic Lumbar Discectomy: A Meta-Analysis

2018 ◽  
Vol 1 (21;1) ◽  
pp. 337-350
Author(s):  
Huiren Tao

Background: Percutaneous endoscopic lumbar discectomy (PELD) is a minimally invasive surgery for the treatment of lumbar disc herniation (LDH) with a smaller incision, decreased damage to soft tissues, faster recovery, and fewer postoperative complications. However, the exactly epidemiological prevalence of recurrent herniation after PELD remains unclear. Objectives: To investigate the epidemiological prevalence of recurrent herniation in patients following PELD and to analyze the potentially related risk factors. Study Design: Meta-analysis and systematic review of prospective and retrospective studies. Methods: We conducted a comprehensive search in MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials that mentioned the incidence of recurrent herniation after PELD. The overall prevalence estimate was calculated by an appropriate meta-analysis. Subgroup analysis, sensitivity analysis, and publication bias assessment were also performed in our study, respectively. Results: Our results showed the overall prevalence of recurrent herniation after PELD was 3.6% (95% CI 3.0-4.3%). The prevalence estimates after percutaneous endoscopic interlaminar discectomy (PEID) and percutaneous endoscopic transforaminal discectomy (PETD) were 4.2% and 3.4%, respectively. Individuals with older age (≥ 50 years) and higher BMI (≥ 25) had increased recurrence rates after PELD than those with younger age (4.3% vs. 2.7%) and normal body mass index (BMI) (4.8% vs. 1.5%). The prevalence was significantly higher at upper discs (5.4%) than that at L4-5 (2.7%) and L5-S1 (3.1%) level. The incidence of recurrent herniation at lateral disc was 4.7%, and the recurrence rate of migrated herniation was 3.8%. In most cases, the recurrent herniation occurred within 6 months postoperatively (accounting for 61.7%). Limitations: A majority of the included articles were relatively low quality retrospective studies with significant heterogeneity among them. Furthermore, owing to the paucity of data focused on recurrence, many potentially predictive factors related to subgroup analyses could not be conducted, which might have influenced the accuracy and comprehensiveness of our meta-analysis. Conclusions: PELD is associated with a certain rate of recurrence (3.6%), which usually occurred within 6 months postoperatively. Older age (≥ 50 years), obesity (BMI ≥ 25), upper lumbar disc and central disc herniation might be independent risk factors for recurrence after PELD; however, different surgical approaches (PETD or PEID), lateral discs, migrated discs and foraminoplasty did not affect the incidence. These factors could be useful in preoperative evaluation, appropriate patient selection and informed consent before PELD. Key words: Percutaneous endoscopic lumbar discectomy, prevalence, recurrent herniation, meta-analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Manyoung Kim ◽  
Sol Lee ◽  
Hyeun-Sung Kim ◽  
Sangyoon Park ◽  
Sang-Yeup Shim ◽  
...  

Background. Among the surgical methods for lumbar disc herniation, open lumbar microdiscectomy is considered the gold standard. Recently, percutaneous endoscopic lumbar discectomy is also commonly performed for lumbar disc herniation for its various strong points. Objectives. The present study aims to examine whether percutaneous endoscopic lumbar discectomy and open lumbar microdiscectomy show better results as surgical treatments for lumbar disc herniation in the Korean population. Methods. In the present meta-analysis, papers on Korean patients who underwent open lumbar microdiscectomy and percutaneous endoscopic lumbar discectomy were searched, both of which are surgical methods to treat lumbar disc herniation. The papers from 1973, when percutaneous endoscopic lumbar discectomy was first introduced, to March 2018 were searched at the databases of MEDLINE, EMBASE, PubMed, and Cochrane Library. Results. Seven papers with 1254 patients were selected. A comparison study revealed that percutaneous endoscopic lumbar discectomy had significantly better results than open lumbar microdiscectomy in the visual analogue pain scale at the final follow-up (leg: mean difference [MD]=-0.35; 95% confidence interval [CI]=-0.61, -0.09; p=0.009; back: MD=-0.79; 95% confidence interval [CI]=-1.42, -0.17; p=0.01), Oswestry Disability Index (MD=-2.12; 95% CI=-4.25, 0.01; p=0.05), operation time (MD=-23.06; 95% CI=-32.42, -13.70; p<0.00001), and hospital stay (MD=-4.64; 95% CI=-6.37, -2.90; p<0.00001). There were no statistical differences in the MacNab classification (odds ratio [OR]=1.02; 95% CI=0.71, 1.49; p=0.90), complication rate (OR=0.72; 95% CI=0.20, 2.62; p=0.62), recurrence rate (OR=0.83; 95% CI=0.50, 1.38; p=0.47), and reoperation rate (OR=1.45; 95% CI=0.89, 2.35; p=0.13). Limitations. All 7 papers used for the meta-analysis were non-RCTs. Some differences (type of surgery (primary or revisional), treatment options before the operation, follow-up period, etc.) existed depending on the selected paper, and the sample size was small as well. Conclusion. While percutaneous endoscopic lumbar discectomy showed better results than open lumbar microdiscectomy in some items, open lumbar microdiscectomy still showed good clinical results, and it is therefore reckoned that a randomized controlled trial with a large sample size would be required in the future to compare these two surgical methods.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Xinbo Wu ◽  
Guoxin Fan ◽  
Xin Gu ◽  
Xiaofei Guan ◽  
Shisheng He

Objective.To describe the two-level percutaneous endoscopic lumbar discectomy (PELD) technique in transforaminal approach for highly migrated disc herniation and investigate its clinical outcomes.Methods.A total of 22 consecutive patients with highly migrated lumbar disc herniation were enrolled for the study from June 2012 to February 2014.Results.There were 12 males and 10 females, with a mean age of 41.1 (range 23–67) years. The mean follow-up period was 18.05 (range 14–33) months. According to the modified MacNab criteria, the clinical outcome at the final follow-up was excellent in 14, good in 6, and fair in 2 patients and the satisfactory rate (excellent and good) was 90.9%. The improvements in VAS and ODI were statistically significant. One patient had recurrent herniation in 18 months after the first surgery and underwent open discectomy. One patient showed symptoms of postoperative dysesthesia (POD), but the POD symptom was transient and partial remission was achieved in two months after conservative treatment.Conclusion.Two-level PELD in transforaminal approach can be a safe and effective procedure for highly migrated disc herniation.


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