RENAL VEIN THROMBOSIS WITH INFRAHEPATIC INFERIOR VENA CAVA EXTENSION IN A CASE OF ANTI dsDNA ANTIBODY NEGATIVE LUPUS NEPHRITIS

2021 ◽  
pp. 53-54
Author(s):  
Abhishek Shetty ◽  
Riddhima Dubhashi

Systemic Lupus Erythematosis (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Anti dsDNA antibody has been considered as a marker of renal disease. Hence elevated levels are expected in patients with Lupus Nephritis (LN). But in a subset of these patients anti dsDNA antibody is negative and this heralds the development of burned out LN (stage 5 LN) which predisposes patients to thrombosis. Prophylactic anticoagulation plays an important role in the management of such patients. We describe a case of a 19 year old female with lupus nephritis and renal vein thrombosis that had extended into the inferior vena cava. Her serology was strikingly signicant for the absence of anti dsDNA antibody. The factors that predispose to the development of venous thrombosis in patients with Lupus Nephritis are discussed. In conclusion, negative anti dsDNA antibodies heralds the development of stage ve Lupus Nephritis which predisposes to thrombosis. Guidelines for prophylactic anticoagulation as per serum albumin levels are also discussed.

2020 ◽  
Vol 54 (3) ◽  
pp. 297-300 ◽  
Author(s):  
Thomas Frederick Barge ◽  
Emma Wilton ◽  
Andrew Wigham

A 23-year-old presenting with an acute history of back pain, leg swelling, and claudication was diagnosed with an extensive iliocaval thrombosis, extending from the popliteal veins into the inferior vena cava (IVC) and left renal vein. He was treated with a combination of endovascular techniques, including EKOS and AngioJet. An underlying congenital IVC stenosis and May-Thurner type iliac vein compression were subsequently treated with venoplasty and stenting. To our knowledge, this is the first report of the use of EKOS for renal vein thrombosis and we highlight the complementary nature of different endovascular techniques for managing complex venous thrombotic disease.


2018 ◽  
Vol 6 (9) ◽  
pp. 1678-1681 ◽  
Author(s):  
Natasha Aluloska ◽  
Snezana Janchevska ◽  
Velibor Tasic

BACKGROUND: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants.CASE REPORT: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopenia in a neonate. The neonate was a macrosomic male born to a mother with hyperglycemia in pregnancy. The baby was born with perinatal asphyxia and early neonatal infection and massive hematuria. Clinical and laboratory examination showed enlarged kidney having corticomedullary differentiation diminished and azotemia. Diagnosis of renal vein thrombosis was suspected by renal ultrasound and confirmed by magnetic urography. Prothrombotic risk factors were evaluated. The child is being managed conservatively. Measures aimed at the prevention of end-stage renal disease because of its poor outcome were highlighted. Despite anticoagulant therapy, the right kidney developed areas of scarring and then atrophy.           CONCLUSION: In this work, we present a patient with multiple entities in the aetiology of non-catheter induced renal and vena cava thrombosis in a neonate. Clinicians should suspect renal vein thrombosis in neonates when presented with early postnatal gross hematuria, palpable abdominal mass and thrombopenia.


Angiology ◽  
1971 ◽  
Vol 22 (3) ◽  
pp. 114-120
Author(s):  
A.C. Papaioannou ◽  
V. Basti-Maouni ◽  
F. Maounis ◽  
M.D. Durst

Urology ◽  
1998 ◽  
Vol 51 (5) ◽  
pp. 829-830 ◽  
Author(s):  
Charles Lash ◽  
Jayant Radhakrishnan ◽  
John C McFadden

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