scholarly journals COMPARISON OF KETOFOLAND PROPOFOL IN INTRACRANIALANEURYSMAL CLIPPING SURGERY: A PROSPECTIVE RANDOMIZED CONTROL STUDY

2020 ◽  
pp. 1-3
Author(s):  
Ajit Bhardwaj ◽  
Arpit * Garg ◽  
Priyanka Arora
Keyword(s):  
Intracranial Aneurysm ◽  
Aneurysmal Subarachnoid Haemorrhage ◽  
Major Goal ◽  
Hemodynamic Stability ◽  
Surgical Clipping ◽  
Aneurysm Neck ◽  
Prospective Randomized Control Study ◽  
Haemodynamic Stability ◽  
Randomized Control ◽  
Control Study

Background: Haemodynamic stability is the major goal of anaesthesia during intracranial aneurysm clipping . In the present study, we compared the effects of ketofol with propofol alone, used as an induction and maintenance agent during surgical clipping of intracranial aneurysm. Material and methods - Forty patients aged 18 to 75 years, posted for aneurysm neck clipping following aneurysmal Subarachnoid haemorrhage (SAH) were included in the study. The patients were randomized into two groups. One group received combination of ketamine and propofol (1:5 ratio) (Group KP) and the other propofol (Group P) for induction and maintenance of anaesthesia. Results - Combination of Ketamine and propofol ( in the ratio of 1:5) which was used in this study provided for better maintenance of Mean Arterial Pressure(MAP) during induction and maintenance of anaesthesia. Conclusion – Ketofol compared to propofol alone provides better hemodynamic stability on induction as well as during maintenance of anaesthesia in intracranial aneurysmal clipping surgery without increasing intracranial pressure.

scholarly journals Comparison of ExPress Implantation and Partial Deep Sclerectomy Combined with ExPress Implantation and Simultaneous Phacoemulsification

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Marietta Frączkiewicz-Skok ◽  
Joanna Konopińska ◽  
Zofia Mariak ◽  
Marek Rękas
Keyword(s):  
Deep Sclerectomy ◽  
Initial Value ◽  
Randomized Control Study ◽  
Surgical Success ◽  
Prospective Randomized Control Study ◽  
Corrected Distance Visual Acuity ◽  
Randomized Control ◽  
Express Group ◽  
Control Study

Background. To compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation and simultaneous phacoemulsification. Patients and Methods. A prospective, randomized control study with 24-month follow-up was performed. 114 eyes were included, of which 42 eyes underwent phacoemulsification with simultaneous implantation of the Ex-Press device (ExPress), and deep sclerectomy with phacoemulsification and simultaneous implantation of the Ex-Press device (DS-ExPress) was performed in 72 eyes. The main outcome measures were intraocular pressure (IOP), corrected distance visual acuity (CDVA), the number of antiglaucoma medications, and the rate of complications. Surgical success was defined as complete (without antiglaucoma medications) with IOP ≤18 mmHg in criterion A, IOP ≤16 mmHg in criterion B, and IOP ≤12 mmHg in criterion C. Satisfactory success was defined as the same IOP levels for individual criteria with a maximum of 2 antiglaucoma medications. Results. Before the procedure, mean IOP in the ExPress group was 17.5 ± 4.7 mmHg; after 24 months, it decreased by 13% to 16.0 ± 3.0 mmHg (P<0.05). In the DS-ExPress group, mean IOP reduced from 16.3 ± 4.4 mmHg to 14.3 ± 3.3 mmHg (P<0.05), which was a 9% reduction compared to the initial value. In the DS-ExPress group, 65.9% of the patients did not use topical pharmacotherapy, and the same is true for 29.2% of the ExPress group (P=0.004). Conclusions. This modification is efficient in surgical treatment of glaucoma, especially when very low postoperative IOP is needed. A less amount of antiglaucoma medicines are needed.

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