scholarly journals Fine Needle Aspiration Cytology in Palpable Breast Lumps: A Retrospective Study

2020 ◽  
Vol 05 (02) ◽  
pp. 134-136
Author(s):  
Poonam Sharma ◽  
Mehnaz Choudhary ◽  
Sonika Gupta ◽  
Subhash Bharadwaj
Keyword(s):  
Retrospective Study ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

scholarly journals Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 780-786
Author(s):  
Shaheen Akter ◽  
Md Jahidul Islam ◽  
Md Shariful Haque
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lumps has been revolutionized and it has high sensitivity and specificity.Aim: In this study we analyze the spectrum of FNAC diagnoses in breast lumps and compare the diagnostic accuracy of fine FNAC in differentiating the benign and malignant lesions of breast lumps with histopathological correlation.Materials & Methods: Two years prospective study was conducted in our institution and in that 490 aspirations, including 6 bilateral were performed. Suppurative and inflammatory lesions were excluded from the total aspirates. The cytological diagnosis was classified into 3 groups benign, suspicious and malignant. After this reporting all the available 94 cases were later subjected to mastectomy or open/excision biopsy and followed-up by histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.Results: A total of 490 FNAC cases were reported including 373 as benign, 4 as suspicious for carcinoma and 113 as carcinoma. Majorities were premenopausal females and commonest age group was 31-40 years. Among them only 94 cases were followed-up by histopathologic confirmation. In histopathological correlation study, we had accuracy rate of 100% for benign lesion and 92.10% for malignant lesion with false negative rate of 7.90% and false positive rate of zero with fine needle aspiration cytology in the diagnosis of palpable breast lump. The overall sensitivity of fine needle aspiration in diagnosing the palpable breast lump is 92.10%, specificity is 100%, positive predictive value is 100% and negative predictive value is 94.91%.Conclusion: FNAC in experienced hands is a very useful tool with very high specificity and rare false positive result. Sensitivity can be further improved with clinical and imaging correlation.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 780-786

scholarly journals A CORRELATIONAL STUDY BETWEEN FINE NEEDLE ASPIRATION CYTOLOGY AND HISTOPATHOLOGY OF PALPABLE BREAST LUMPS

2021 ◽  
Vol 7 (4) ◽  
pp. 117-123
Author(s):  
Vilas P. Kulkarni ◽  
Abhijit S. Rayate ◽  
Cristine Ann Thomas ◽  
Nikhil R. Barhate ◽  
Gaurav J. Gaikwad ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Incidence of breast malignancies has been rising. Any breast lump needs to differentiated as surgery may not be required in all cases. The National Health Services Breast Screening Program recommends Fine Needle aspiration cytology (FNAC) as a non-operative diagnostic tool. FNAC is a cheap, readily available, relatively painless, repeatable and patient-friendly investigation with good sensitivity and specificity. FNAC does not yield a tissue diagnosis as opposed to core biopsy, however, a well-performed FNAC and reporting by an expert pathologist help to avoid unnecessary surgeries in benign lesions where only conservative management or elective surgery is needed. Aims: To study the correlation between FNAC and histopathological reports of palpable breast lumps. Materials and method: We conducted an observational study at a tertiary care hospital. The study included 237 patients of palpable breast lumps who had undergone FNAC, excisional biopsy and histopathology in the same institution. The results of FNAC and histopathology reports were correlated into benign and malignant categories. Results: There were 225 women and 12 men in this study. FNAC had reported 20 malignant (C4+C5) cases and 217 benign cases. Histopathology revealed 21 malignant cases and 216 benign cases. We observed a sensitivity of 90.48%, specificity of 99.54%, a positive predictive value of 95%, a negative predictive value of 99.08%, a concordance of 92.41%, a diagnostic accuracy of 98.73% and a negative likelihood ratio of 0.1 for FNAC. Conclusions: Besides other advantages, FNAC of a breast lesion is reliable enough to rule out malignancy.

scholarly journals Comparative study of aspiration and non-aspiration cytology of palpable breast lumps and correlation with histopathology

2014 ◽  
Vol 4 (8) ◽  
pp. 639-643 ◽  
Author(s):  
S Koirala
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Diagnostic Efficiency ◽  
Aspiration Cytology ◽  
Diagnostic Modality ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: Breast lump is one of the most common presentations in surgical outpatient departments with anxiety regarding a possible malignancy. Hence a quick diagnosis of a lump in the breast is essential. Fine needle aspiration cytology is an ideal initial diagnostic modality in breast lumps. There is an alternative method of performing needle aspiration, known as fine needle capillary cytology where the specimen is obtained using just a needle without aspiration.Materials and Methods: This hospital-based cross sectional analytical study was carried out in Department of Pathology in National Academy of Medical Sciences, Bir Hospital for one year. The objective of this study was to compare aspiration and non-aspiration cytology of palpable breast lumps and correlation with histopathology.Results: The five criteria scored for each technique were background blood, amount of cellular material, cellular degeneration, cellular trauma and architectural preservation. Compared to fine needle aspiration cytology, fine needle capillary cytology yields less bloody smears with minimal degenerative changes and offers more diagnostically superior specimens. Fine needle aspiration cytology, on the other hand, gives a good yield of diagnostic material.Conclusion: Fine needle aspiration cytology and fine needle capillary cytology are quick, easy, safe and cost-effective techniques. . A high sensitivity and specificity of cytological diagnosis in this study proves that it is comparable to final histology report in its diagnostic efficiency. Thus, fine needle aspiration cytology is a very important preliminary diagnostic test in palpable breast lumps and the results show a high degree of correlation with the final histopathology report.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11501 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 639-643

scholarly journals Utility of fine-needle aspiration cytology as a screening tool in diagnosis of breast lumps

2017 ◽  
Vol 4 (4) ◽  
pp. 1171
Author(s):  
Rajat Gupta ◽  
Deepika Dewan ◽  
Dinesh Kumar ◽  
Rameshwar Sharma
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Ductal Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: Fine-needle aspiration cytology (FNAC) has proved to be a rapid, safe, cost effective and good screening or initial diagnostic tool for early diagnosis and management of palpable breast swellings. The present study was conducted to describe and categorize various breast lesions on FNAC. The study also aimed to find out the diagnostic accuracy of FNAC procedure.Methods: This study was carried out on 175 patients who presented with palpable breast swellings in Government Hospital Gandhi Nagar, Jammu, Jammu and Kashmir, India and subsequently referred to Pathology Department of Govt. Hospital Gandhi Nagar over a period of two years and eight months from January 2013 to September 2015. Lesions were categorized as per cytomorphological features obtained on FNAC. Histopathological correlation was done on 68 cases inclusive of all malignant cases.Results: 156 (89%) cases were categorized as benign and 19 cases (11%) as malignant on FNAC out of 175 cases. The most common benign lesion was fibro adenoma (41%) and the most common breast carcinoma was ductal carcinoma (65%). Sensitivity, specificity, positive predictive value, negative predictive value, LR+ and LR-  came out to be 85%, 95.8%, 89%, 93.8%, 20.4 and 0.15 respectively.Conclusions: FNAC is a good screening procedure for initial diagnosis of breast lumps. It is highly useful procedure in secondary care centres due to its cost effectiveness, rapid and safe nature.

scholarly journals Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Adetola Olubunmi Daramola ◽  
Mosebolatan Olatokunboh Odubanjo ◽  
Fred John Obiajulu ◽  
Nzechukwu Zimudo Ikeri ◽  
Adekunbiola Aina Fehintola Banjo
Keyword(s):  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background. Management of breast lumps can be challenging in resource poor settings. Fine-needle aspiration cytology (FNAC) especially when used with cell block can help improve affordability for the patients.Objective. To determine the diagnostic accuracy of FNAC of palpable breast lesions within a 5-year period.Methods. The findings obtained from FNAC of palpable breast lumps seen at the FNAC clinic of our department from January 2007 to December 2011 were retrieved and correlated with findings on histology of excisional biopsies.Results. A total of 1790 patients had FNAC of breast lumps during the 5-year period; 436 of them subsequently had biopsies. Our results compare favourably with the measures of test performance of the UK NHS Breast Screening Programme shown in brackets: absolute sensitivity 95.4% (>70%), complete sensitivity 99.2% (>90%), full specificity 88.9% (>65%), positive predictive value 99.6% (>99%), false-negative rate 0.8% (<4%), false-positive rate 0.4% (<0.5%), inadequate rate 3.2% (<15%), and suspicious rate 10.2% (<15%).Conclusion. Breast FNACs compare very well with histology of excisional biopsies and in experienced hands are extremely useful in the management of breast lumps. Further studies assessing the diagnostic accuracy of FNAC and cell blocks in our setting are recommended.

scholarly journals Use of Fine-Needle Aspiration in the Evaluation of Breast Lumps

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Mulazim Hussain Bukhari ◽  
Madiha Arshad ◽  
Shahid Jamal ◽  
Shahida Niazi ◽  
Shahid Bashir ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Ductal Carcinoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background. A study was designed to see the role of fine needle aspiration cytology (FNAC) in palpable breast lumps. Materials and Methods. Four hundred and twenty five (425) patients came to the Department of Pathology King Edward Medical University, Lahore in four years for FNAC of their palpable breast masses from June 2006 to June 2010. FNAC diagnosis was compared with histological diagnosis to see the accuracy of fine needle aspiration cytology for neoplastic lesions. Results. There were 271/425 benign, 120/425 malignant, and 32/425 suspicious smears. Inadequate samples were repeated twice or thrice, and the degree of success was improved with consecutive repeating approaches. The frequency of inadequacy declined from 86 to 18, and 2 for first, second and third attempts, respectively. The number of repeats increased the diagnostic accuracy of aspirates which is statistically significant (). Invasive ductal carcinoma was the most commonly reported lesion with maximum incidence in the 4th, 5th, and 6th decades followed by invasive lobular carcinoma and other malignant lesions. The sensitivity, specificity, accuracy, negative predictive value, and the positive predictive value of FNAC was 98%, 100%, 98%, 100%, and 97%, respectively. Conclusion. FNAC serves as a rapid, economical, and reliable tool for the diagnosis of palpable breast lesions because the cytopathological examination of these lesions before operation or treatment serves as an important diagnostic modality.

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