Results of pollen monitoring and features of seasonal allergic rhinitis in Samara

Background. The objective was to study the taxonomic diversity of the concentration of pollen, its changes and peculiarities of the course of seasonal allergic rhinitis in Samara city. Methods. Pollen was located with gravimetric method on the glass, covered with a special mixture. Clinical and allergological examination conducted among 775 children aged from 5 to 18 years and 692 adults with symptoms of rhinitis. Results. Registered three periods of increase of concentration of pollen: spring period, summer period and summer-autumn period. The major taxa in the spring was pollen Populus - 49% and Betula - 27% during this period. In the summer period dominated pollen was Pinus - 37%, Poaceae - 28% and Betula - 22%. In summer-autumn period prevailed pollen grains Ambrosia - 63% and Artemisia - 10%, of the total number of pollen grains for this period. Clinical and allergological studies have shown that the proportion of patients with seasonal allergic rhinitis is 78% among the total number of patients with allergic rhinitis. Isolated form of seasonal allergic rhinitis was diagnosed in 22% of children and in 20% of adults. Patients of this group are allergic to pollen, weeds and compositae revealed in 68%, trees - 20%, cereals - 12% of cases. Conclusion. Qualitative and quantitative composition of aeropalynologic spectrum was established and showed the peculiarities of the course of seasonal allergic rhinitis in Samara city.

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Causal Relationships Among Pollen Counts, Tweet Numbers, and Patient Numbers for Seasonal Allergic Rhinitis Surveillance: Retrospective Analysis (Preprint)

10.2196/preprints.10450 ◽

2018 ◽

Author(s):

Shoko Wakamiya ◽

Shoji Matsune ◽

Kimihiro Okubo ◽

Eiji Aramaki

Keyword(s):

Social Media ◽

Allergic Rhinitis ◽

Seasonal Allergic Rhinitis ◽

Japanese Cedar ◽

Pollen Count ◽

Causal Relationships ◽

Social Media Data ◽

Pollen Counts ◽

Number Of Patients ◽

Media Data

BACKGROUND Health-related social media data are increasingly used in disease-surveillance studies, which have demonstrated moderately high correlations between the number of social media posts and the number of patients. However, there is a need to understand the causal relationship between the behavior of social media users and the actual number of patients in order to increase the credibility of disease surveillance based on social media data. OBJECTIVE This study aimed to clarify the causal relationships among pollen count, the posting behavior of social media users, and the number of patients with seasonal allergic rhinitis in the real world. METHODS This analysis was conducted using datasets of pollen counts, tweet numbers, and numbers of patients with seasonal allergic rhinitis from Kanagawa Prefecture, Japan. We examined daily pollen counts for Japanese cedar (the major cause of seasonal allergic rhinitis in Japan) and hinoki cypress (which commonly complicates seasonal allergic rhinitis) from February 1 to May 31, 2017. The daily numbers of tweets that included the keyword “kafunshō” (or seasonal allergic rhinitis) were calculated between January 1 and May 31, 2017. Daily numbers of patients with seasonal allergic rhinitis from January 1 to May 31, 2017, were obtained from three healthcare institutes that participated in the study. The Granger causality test was used to examine the causal relationships among pollen count, tweet numbers, and the number of patients with seasonal allergic rhinitis from February to May 2017. To determine if time-variant factors affect these causal relationships, we analyzed the main seasonal allergic rhinitis phase (February to April) when Japanese cedar trees actively produce and release pollen. RESULTS Increases in pollen count were found to increase the number of tweets during the overall study period (P=.04), but not the main seasonal allergic rhinitis phase (P=.05). In contrast, increases in pollen count were found to increase patient numbers in both the study period (P=.04) and the main seasonal allergic rhinitis phase (P=.01). Increases in the number of tweets increased the patient numbers during the main seasonal allergic rhinitis phase (P=.02), but not the overall study period (P=.89). Patient numbers did not affect the number of tweets in both the overall study period (P=.24) and the main seasonal allergic rhinitis phase (P=.47). CONCLUSIONS Understanding the causal relationships among pollen counts, tweet numbers, and numbers of patients with seasonal allergic rhinitis is an important step to increasing the credibility of surveillance systems that use social media data. Further in-depth studies are needed to identify the determinants of social media posts described in this exploratory analysis.

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EFFECT OF MULTILEVEL AIR CLEANING FOR PATIENTS WITH SEASONAL ALLERGIC RHINITIS AND ASTHMA

Rossiiskii Allergologicheskii ZHurnal ◽

10.36691/rja718 ◽

2012 ◽

Vol 9 (5) ◽

pp. 60-68

Author(s):

A V Averyanov ◽

O G Elisyutma ◽

E S Fedenko ◽

S I Sokurenko ◽

T V Borisova ◽

...

Keyword(s):

Allergic Rhinitis ◽

Lung Function ◽

Clinical Improvement ◽

Seasonal Allergic Rhinitis ◽

Pollen Grains ◽

Controlled Study ◽

Comprehensive Treatment ◽

Air Cleaning ◽

Air Space ◽

Cleaning Technology

A randomized placebo-controlled study to evaluate the effectiveness of the air cleaning technology with device IQAir HealthPro Series Model 250 (Switzerland) for comprehensive treatment of patients with seasonal allergic rhinitis and bronchial asthma was carried out. The significant reduction in the number of pollen grains in the air space and the clinical improvement was demonstrated, but no effect on lung function, blood and nasal mucus eosinophilia was revealed.

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Clinically relevant effect of rupatadine 20 mg and 10 mg in seasonal allergic rhinitis: a pooled responder analysis

Clinical and Translational Allergy ◽

10.1186/s13601-019-0293-4 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Joaquim Mullol ◽

Iñaki Izquierdo ◽

Kimihiro Okubo ◽

Giorgio Walter Canonica ◽

Jean Bousquet ◽

...

Keyword(s):

Allergic Rhinitis ◽

Placebo Group ◽

Symptom Score ◽

Seasonal Allergic Rhinitis ◽

Complete Response ◽

Dependent Manner ◽

Responder Analysis ◽

Superior Efficacy ◽

Number Of Patients ◽

Symptom Scores

Abstract Background Different clinical trials showed the superior efficacy of rupatadine compared to placebo at improving seasonal allergic rhinitis (SAR) symptoms, but no study has assessed if the response promoted is clinically meaningful. Methods This study is a pooled analysis of data of seven randomized, double-blind, placebo-controlled SAR studies comparing responder proportions upon treatment with rupatadine (10 or 20 mg) or placebo. We evaluated the following symptom scores at baseline (Visit 1) and over 14 days of treatment: Total 4 Nasal Symptom Score (T4NSS), Total 2 Ocular Symptom Score (T2OSS) and Total 6 Symptom Score (T6SS). The proportion of responders (50% and 75% response) and the time to response were compared between groups on days 7 (Visit 2) and 14 (Visit 3). Responder rates were compared between groups on days 7 and 14 for the complete/near-to-complete response for T4NSS (TN4SS score ≤ 2 and each symptom score ≤ 1) and T6SS (T6SS score ≤ 3 and each symptom score ≤ 1). Results Data from 1470 patients were analyzed: 332 treated with placebo, 662 with rupatadine 10 mg and 476 with rupatadine 20 mg. The reduction in T4NSS, T2OSS and T6SS over 14 days of treatment relative to baseline was statistically higher in rupatadine groups vs the placebo group, with greater improvements in the 20 mg group. A statistically higher proportion of patients reached the 50% and 75% response for T4NSS, T2OSS and T6SS in rupatadine groups compared to the placebo group across the visits. Among rupatadine-treated patients, those receiving 20 mg compared favourably for both cut-off responses. The time to achieve a proportion of responders was shorter in the rupatadine 20 mg group than in the rupatadine 10 mg and placebo groups for all the symptom scores. The number of patients who achieved a complete/near-to-complete response for both symptom scores was higher in rupatadine groups than in the placebo group, with higher proportions in the 20 mg group. Conclusions This responder analysis confirms the superior efficacy of rupatadine vs placebo to treat SAR. Rupatadine promoted higher proportions of responders according to stringent response criteria and in a dose-dependent manner, with faster and higher response rates in the 20 mg group.

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