scholarly journals Botulinum toxin injections after surgery for Hirschsprung disease: Systematic review and meta-analysis

2019 ◽  
Vol 25 (25) ◽  
pp. 3268-3280 ◽  
Author(s):  
Daniëlle Roorda ◽  
Zarah AM Abeln ◽  
Jaap Oosterlaan ◽  
Lodewijk WE van Heurn ◽  
Joep PM Derikx
Keyword(s):  
Systematic Review ◽  
Botulinum Toxin ◽  
Meta Analysis ◽  
Hirschsprung Disease ◽  
Botulinum Toxin Injections

scholarly journals Fascial closure in giant ventral hernias after preoperative botulinum toxin a and progressive pneumoperitoneum: A systematic review and meta-analysis

Surgery ◽  
2021 ◽  
Author(s):  
Mathilde Maria Johanna van Rooijen ◽  
Yagmur Yurtkap ◽  
Mathias Allaeys ◽  
Nabeel Ibrahim ◽  
Frederik Berrevoet ◽  
...  
Keyword(s):  
Systematic Review ◽  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Meta Analysis ◽  
Fascial Closure ◽  
Toxin A ◽  
Ventral Hernias

scholarly journals CGRP-antibodies, topiramate and botulinum toxin type A in episodic and chronic migraine: A systematic review and meta-analysis

Cephalalgia ◽  
2021 ◽  
pp. 033310242110181
Author(s):  
Florian Frank ◽  
Hanno Ulmer ◽  
Victoria Sidoroff ◽  
Gregor Broessner
Keyword(s):  
Systematic Review ◽  
Monoclonal Antibodies ◽  
Botulinum Toxin ◽  
Response Rate ◽  
Meta Analysis ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Response Rates ◽  
Botulinum Toxin Type ◽  
Odds Ratios

Background The approval of monoclonal antibodies for prevention of migraine has revolutionized treatment for patients. Oral preventatives are still considered first line treatments as head-to-head trials comparing them with antibodies are lacking. Methods The main purpose of this study was to provide a comparative overview of the efficacy of three commonly prescribed migraine preventative medication classes. For this systematic review and meta-analysis, we searched the databases CENTRAL, EMBASE, and MEDLINE until 20 March 2020. We included RCTs reporting the 50% response rates for topiramate, Botulinum Toxin Type A and monoclonal antibodies against CGRP(r). Studies were excluded if response rates were not reported, treatment allocation was unclear, or if study quality was insufficient. Primary outcome measure were the 50% response rates. The pooled odds ratios with 95% confidence intervals were calculated with the random effects model. The study was registered at PROSPERO (CRD42020222880). Findings We identified 6552 reports. Thirty-two were eligible for our review. Studies assessing monoclonal antibodies included 13,302 patients and yielded pooled odds ratios for the 50% response rate of 2.30 (CI: 2.11–2.50). Topiramate had an overall effect estimate of 2.70 (CI: 1.97–3.69) with 1989 included patients and Botulinum Toxin Type A achieved 1.28 (CI: 0.98–1. 67) with 2472 patients included. Interpretation Topiramate, botulinum toxin type A and monoclonal antibodies showed higher odds ratios in achieving a 50% response rate compared to placebo. Topiramate numerically demonstrated the greatest effect size but also the highest drop-out rate.

scholarly journals Botulinum toxin-A for the treatment of neuralgia: a systematic review and meta-analysis

2018 ◽  
Vol Volume 11 ◽  
pp. 2343-2351 ◽  
Author(s):  
Fan Meng ◽  
Ke Peng ◽  
Jian-Ping Yang ◽  
Fu-Hai Ji ◽  
Fan Xia ◽  
...  
Keyword(s):  
Systematic Review ◽  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Meta Analysis ◽  
Toxin A

scholarly journals Short and long-term quality of life outcomes in children after surgery for Hirschsprung Disease or Anorectal Malformations: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Irina Oltean ◽  
Emily Beveridge ◽  
Lamia Hayawi ◽  
Vid Bijelic ◽  
Ahmed Nasr
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Psychosocial Functioning ◽  
Meta Analysis ◽  
Hirschsprung Disease ◽  
Cochrane Collaboration ◽  
Anorectal Malformations ◽  
Case Control Studies ◽  
Social And Emotional

There is paucity of evidence examining quality of life in children with HD and ARM prioritizing dimensions other than physical functioning, such as psychosocial functioning in a precise manner. As such, we have developed a systematic review protocol to narratively and quantitatively summarize the physical and psychosocial functioning of children affected by HD and ARM in hopes of addressing this limitation. The following databases were searched on Nov 5, 2019: MEDLINE including Epub Ahead of Print, In-Process & Other Non-Indexed Citations (1946 to October 25, 2019) and Embase (1947 to 2019 October 25) and the CENTRAL Trials Registry of the Cochrane Collaboration (September 2019 Issue) using the Ovid interface. Searches were limited to English, to journal articles, and articles published since 2006. This review will identify retrospective and prospective cohort studies, case-control studies, case studies with greater than 5 participants, and randomized-control trials where the quality of life (i.e., physical and/or social functioning) of children aged 0-18 years with either anorectal malformations or Hirschprung’s disease is reported by children or parent proxies. Understanding the quality of life of children affected by HD and ARM after surgery will help clinical practitioners, specifically surgeons, create tailored and comprehensive protocols for managing these diseases while recognising the physical, social, and emotional toll they can inflict on children.

Sign in / Sign up

Export Citation Format

Share Document