The enantioselective synthesis of (S)-(+)-mianserin and (S)-(+)-epinastine
2015 ◽
Vol 11
◽
pp. 1509-1513
◽
Keyword(s):
A simple enantioselective synthetic procedure for the preparation of mianserin and epinastine in optically pure form is described. The key step in the synthetic pathway is the asymmetric reduction of the cyclic imine using asymmetric transfer hydrogenation conditions.
2015 ◽
Vol 2015
(29)
◽
pp. 6503-6514
◽
2019 ◽
Vol 361
(17)
◽
pp. 4106-4110
◽
2013 ◽
Vol 24
(4)
◽
pp. 196-201
◽
2014 ◽
Vol 79
(6)
◽
pp. 2666-2681
◽
2005 ◽
Vol 136
(9)
◽
pp. 1619-1627
◽