INFLUENCE OF NEW METAL-COMPLEX SUBSTANCES ON THE RESISTANCE TO ACUTE HYPOBARIC HYPOXIA IN MICE

2021 ◽  
Vol 20 (1) ◽  
pp. 26-32
Author(s):  
A.E. Belenky ◽  
A.V. Evseev ◽  
M.A. Evseeva ◽  
D.V. Surmenev ◽  
D.V. Sosin ◽  
...  
Keyword(s):  
Metal Complex ◽  
Hypobaric Hypoxia ◽  
Acute Hypobaric Hypoxia

scholarly journals Study of antihypoxic activities of metal complex selenium containing substances after their parenteral and enteralintroductions

2012 ◽  
Vol 10 (3) ◽  
pp. 28-34
Author(s):  
Denis Vladimirovich Sosin ◽  
Andrey Viktorovich Yevseyev ◽  
Edgar Andreyevich Parfenov ◽  
Vitaliy Andreyevich Pravdivtsev ◽  
Marina Anatolyevna Yevseyeva ◽  
...  
Keyword(s):  
Metal Complex ◽  
Hypobaric Hypoxia ◽  
Protective Action ◽  
Complex Compounds ◽  
Acute Hypobaric Hypoxia ◽  
Hypercapnic Hypoxia ◽  
First Time

In experiments on mice undergone to an acute hypercapnic hypoxia and an acute hypobaric hypoxia a screening of antihypoxants among new selenium containing metal complex substances was performed after their intra-abdominal and oral introductions. It was found that substances πQ1983 and πQ2170 on both models of hypoxia make the defensive effects surpassing actions well-known antihypoxants such as amthizole and bemythil. It was shown that antihypoxiс affects of studied substances depend on their caused hypothermia. For the first time the protective action of selenium containing metal complex compounds was demonstrated after their introduction per os.

Acute Hypobaric Hypoxia (5486 m) Induces Greater Pulmonary HIF-1 Activation in Hilltop Compared to Madison Rats

2007 ◽  
Vol 8 (4) ◽  
pp. 312-321 ◽  
Author(s):  
Barbara J. Engebretsen ◽  
David Irwin ◽  
Maria E. Valdez ◽  
Mary K. O'Donovan ◽  
Alan Tucker ◽  
...  
Keyword(s):  
Hypobaric Hypoxia ◽  
Acute Hypobaric Hypoxia

Huperzine A Ameliorates Cognitive Deficits and Oxidative Stress in the Hippocampus of Rats Exposed to Acute Hypobaric Hypoxia

2012 ◽  
Vol 37 (9) ◽  
pp. 2042-2052 ◽  
Author(s):  
Qinghai Shi ◽  
Jianfeng Fu ◽  
Di Ge ◽  
Yan He ◽  
Jihua Ran ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cognitive Deficits ◽  
Hypobaric Hypoxia ◽  
Huperzine A ◽  
Acute Hypobaric Hypoxia ◽  
And Oxidative Stress

scholarly journals Adrenomedullin Expression is Up-regulated by Acute Hypobaric Hypoxia in the Cerebral Cortex of the Adult Rat

2008 ◽  
Vol 18 (3) ◽  
pp. 434-442 ◽  
Author(s):  
Julia Serrano ◽  
Ana Patricia Fernández ◽  
Jaime Sánchez ◽  
José Rodrigo ◽  
Alfredo Martínez
Keyword(s):  
Cerebral Cortex ◽  
Hypobaric Hypoxia ◽  
Acute Hypobaric Hypoxia ◽  
Adult Rat

Effect of physical training on the capacity to secrete epinephrine

1988 ◽  
Vol 64 (1) ◽  
pp. 11-16 ◽  
Author(s):  
M. Kjaer ◽  
H. Galbo
Keyword(s):  
Hypobaric Hypoxia ◽  
Plasma Norepinephrine ◽  
Plasma Epinephrine ◽  
O2 Uptake ◽  
Acute Hypobaric Hypoxia ◽  
Arterial Pco2 ◽  
Norepinephrine Concentration ◽  
Arterial Po2 ◽  
Secretory Capacity ◽  
Epinephrine Concentration

Epinephrine responses to hypoglycemia and to identical relative work loads have been shown to be higher in endurance-trained athletes than in untrained subjects. To test the hypothesis that training increases the adrenal medullary secretory capacity, we studied the effects of glucagon (1 mg/70 kg iv), acute hypercapnia (inspired O2 fraction = 7%), and acute hypobaric hypoxia (inspired Po2 = 87 Torr), respectively, on the epinephrine concentration in arterialized hand vein blood in eight endurance-trained athletes [T, O2 uptake = 66 (62-70) ml.min-1.kg-1] and seven sedentary males [C, O2 uptake = 46 (41-50)]. In response to identical increments in glucagon concentrations, plasma epinephrine increased more in T than in C subjects [0.87 +/- 0.11 vs. 0.38 +/- 0.14 (SE) nmol/l, P less than 0.05]. In response to hypercapnia [arterial PCO2 = 56 +/- 0.7 Torr (T) and 55 +/- 0.4 (C), P greater than 0.05], the increment in epinephrine was significant in T (0.38 +/- 0.11 nmol/l) but not (P less than 0.1) in C subjects (0.22 +/- 0.11). Hypoxia [arterial PO2 = 42 +/- 2 Torr (T) and 41 +/- 2 (C), P greater than 0.05] increased epinephrine in T (0.22 +/- 0.10 nmol/l, P less than 0.05) but not in C subjects (0.01 +/- 0.07). The plasma norepinephrine concentration never changed, whereas heart rate always increased, the increase being higher (P less than 0.05) in T than in C subjects only during hypercapnia. The results indicate that training increases the capacity to secrete epinephrine.

Voluntary Muscle Function after Creatine Supplementation in Acute Hypobaric Hypoxia

2006 ◽  
Vol 38 (8) ◽  
pp. 1418-1424 ◽  
Author(s):  
CAROL J. BAKER-FULCO ◽  
CHARLES S. FULCO ◽  
MARK D. KELLOGG ◽  
ELLEN GLICKMAN ◽  
ANDREW J. YOUNG
Keyword(s):  
Muscle Function ◽  
Hypobaric Hypoxia ◽  
Creatine Supplementation ◽  
Acute Hypobaric Hypoxia ◽  
Voluntary Muscle
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