An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

Journal of Visualized Experiments ◽

10.3791/60449 ◽

2020 ◽

Author(s):

Ahmed Ali ◽

Yasmine Abouleila ◽

Arno Germond

Keyword(s):

Mass Spectrometry ◽

Raman Spectroscopy ◽

Single Cell ◽

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Single-Cell Screening of Tamoxifen Abundance and Effect Using Mass Spectrometry and Raman-Spectroscopy

Analytical Chemistry ◽

10.1021/acs.analchem.8b04393 ◽

2019 ◽

Vol 91 (4) ◽

pp. 2710-2718 ◽

Author(s):

Ahmed Ali ◽

Yasmine Abouleila ◽

Yoshihiro Shimizu ◽

Eiso Hiyama ◽

Tomonobu M. Watanabe ◽

...

Keyword(s):

Mass Spectrometry ◽

Raman Spectroscopy ◽

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Faculty Opinions recommendation of In vivo lipidomics using single-cell Raman spectroscopy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9023956.9591055 ◽

2011 ◽

Author(s):

Julia Kehr

Keyword(s):

Raman Spectroscopy ◽

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In Vivo Subcellular Mass Spectrometry Enables Proteo‐Metabolomic Single‐cell Systems Biology in a Chordate Embryo Developing to a Normally Behaving Tadpole (X. laevis)

Angewandte Chemie ◽

10.1002/ange.202100923 ◽

2021 ◽

Author(s):

Camille Lombard-Banek ◽

Jie Li ◽

Erika P. Portero ◽

Rosemary M. Onjiko ◽

Chase D. Singer ◽

...

Keyword(s):

Mass Spectrometry ◽

Systems Biology ◽

Single Cell ◽

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Chemical Tagging Assisted Mass Spectrometry Analysis Enables Sensitive Determination of Phosphorylated Compounds in a Single Cell

Analytical Chemistry ◽

10.1021/acs.analchem.1c00915 ◽

2021 ◽

Vol 93 (17) ◽

pp. 6848-6856

Author(s):

Fei-Long Liu ◽

Tian-Tian Ye ◽

Jiang-Hui Ding ◽

Xiao-Ming Yin ◽

Xiao-Ke Yang ◽

...

Keyword(s):

Mass Spectrometry ◽

Single Cell ◽

Mass Spectrometry Analysis ◽

Spectrometry Analysis ◽

Phosphorylated Compounds ◽

Chemical Tagging ◽

Sensitive Determination

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Frontispiz: In Vivo Subcellular Mass Spectrometry Enables Proteo‐Metabolomic Single‐Cell Systems Biology in a Chordate Embryo Developing to a Normally Behaving Tadpole ( X. laevis )

Angewandte Chemie ◽

10.1002/ange.202182362 ◽

2021 ◽

Vol 133 (23) ◽

Author(s):

Camille Lombard‐Banek ◽

Jie Li ◽

Erika P. Portero ◽

Rosemary M. Onjiko ◽

Chase D. Singer ◽

...

Keyword(s):

Mass Spectrometry ◽

Systems Biology ◽

Single Cell ◽

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Single-cell metabolite analysis by electrospray ionization mass spectrometry

TrAC Trends in Analytical Chemistry ◽

10.1016/j.trac.2021.116351 ◽

2021 ◽

pp. 116351

Author(s):

Guizhen Zhu ◽

Yunlong Shao ◽

Yuanxing Liu ◽

Tong Pei ◽

Lijie Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Single Cell ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Metabolite Analysis

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Real-Time Chiral Metabolic Monitoring of Single Cell Using Microchip Electrophoresis Coupled with Electrospray Ionization Mass Spectrometry

ChemistrySelect ◽

10.1002/slct.201600748 ◽

2016 ◽

Vol 1 (17) ◽

pp. 5554-5560 ◽

Author(s):

Xiangtang Li ◽

Shulin Zhao ◽

Yi-Ming Liu

Keyword(s):

Mass Spectrometry ◽

Single Cell ◽

Electrospray Ionization ◽

Real Time ◽

Electrospray Ionization Mass Spectrometry ◽

Microchip Electrophoresis ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Metabolic Monitoring

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Single-cell discrimination based on optical tweezers Raman spectroscopy

Chinese Science Bulletin ◽

10.1007/s11434-013-5721-6 ◽

2013 ◽

Vol 58 (21) ◽

pp. 2594-2600 ◽

Author(s):

HongFei Ma ◽

Yong Zhang ◽

AnPei Ye

Keyword(s):

Raman Spectroscopy ◽

Single Cell ◽

Optical Tweezers ◽

Cell Discrimination

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Single-Cell Mass Spectrometry for Discovery Proteomics: Quantifying Translational Cell Heterogeneity in the 16-Cell Frog (Xenopus) Embryo

Angewandte Chemie International Edition ◽

10.1002/anie.201510411 ◽

2016 ◽

Vol 55 (7) ◽

pp. 2454-2458 ◽

Author(s):

Camille Lombard-Banek ◽

Sally A. Moody ◽

Peter Nemes

Keyword(s):

Mass Spectrometry ◽

Single Cell ◽

Cell Mass ◽

Xenopus Embryo ◽

Cell Heterogeneity ◽

Cell Mass Spectrometry

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Dynamic characterization of drug resistance and heterogeneity of the gastric cancer cell BGC823 using single-cell Raman spectroscopy

The Analyst ◽

10.1039/c7an01287j ◽

2018 ◽

Vol 143 (1) ◽

pp. 164-174 ◽

Author(s):

Yong Zhang ◽

Ludi Jin ◽

Jingjing Xu ◽

Yuezhou Yu ◽

Lin Shen ◽

...

Keyword(s):

Gastric Cancer ◽

Raman Spectroscopy ◽

Drug Resistance ◽

Gastric Carcinoma ◽

Single Cell ◽

Gastric Cancer Cell ◽

Carcinoma Cells ◽

Dynamic Characterization ◽

Human Gastric Carcinoma Cells

Drug resistance and heterogeneous characteristics of human gastric carcinoma cells (BGC823) under the treatment of paclitaxel (PTX) were investigated using single-cell Raman spectroscopy (RS).

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