Multimodal Imaging of Atypical Acute Syphilitic Posterior Placoid Chorioretinitis Mimicking a White Dot Syndrome

2019 ◽  
Vol 50 (2) ◽  
pp. e52-e55 ◽  
Author(s):  
S. Amal Hussnain ◽  
Orly Gal-Or ◽  
Armand Daccache ◽  
Jeffrey D. Klausner ◽  
Lawrence Yannuzzi
Ophthalmology ◽  
2015 ◽  
Vol 122 (9) ◽  
pp. 1836 ◽  
Author(s):  
Abtin Shahlaee ◽  
Bryan Hong ◽  
Jayanth Sridhar ◽  
Sonia Mehta

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Miaoling Li ◽  
Xiongze Zhang ◽  
Feng Wen

Purpose. To investigate the fundus autofluorescence (FAF) spectrum of punctate inner choroidopathy (PIC).Methods. This is a retrospective observational case series of 27 consecutive patients with PIC admitted from October 2013 to March 2015, who underwent short-wavelength- (SW-) and near-infrared- (NIR-) FAF imaging, spectral domain optical coherence tomography (SD-OCT), fluorescein angiography (FA), and indocyanine green angiography (ICGA).Results. There were three primary findings on the FAF imaging of patients with PIC. First, active PIC lesions revealed hypoautofluorescent spots with hyperautofluorescent margin. After the lesions regressed, the hyperautoflurescent margin faded. Second, subclinical and most of the atrophic PIC lesions appeared to be hypoautofluorescent spots. But subclinical PIC lesions were more distinctive on NIR-FAF imaging than on SW-FAF imaging. Third, hypoautofluorescent spots of PIC lesions coexisted with hyperautofluorescent patches on SW-FAF imaging. These hyperautofluorescent patches were demonstrated to be multiple evanescent white dot syndrome (MEWDS) or acute zonal occult outer retinopathy (AZOOR) lesions by subsequent multimodal imaging and faded during follow-up examinations.Conclusion. FAF imaging helps in noninvasively tracking the evolution of PIC lesions and identifying the combined MEWDS or AZOOR lesions, complementary to SD-OCT and angiographic studies.


Retina ◽  
2016 ◽  
Vol 36 (1) ◽  
pp. 64-74 ◽  
Author(s):  
Marcela Marsiglia ◽  
Roberto Gallego-Pinazo ◽  
Eduardo Cunha de Souza ◽  
Marion R. Munk ◽  
Suquin Yu ◽  
...  

2017 ◽  
Vol 65 (11) ◽  
pp. 1209 ◽  
Author(s):  
Giuseppe Casalino ◽  
Ugo Introini ◽  
CarlosE Pavesio ◽  
Francesco Bandello

2013 ◽  
Vol 44 (3) ◽  
pp. 296-300 ◽  
Author(s):  
Adam Boretsky ◽  
Sarah Mirza ◽  
Faraz Khan ◽  
Massoud Motamedi ◽  
Frederik J.G.M. van Kuijk

Author(s):  
S. Kammoun ◽  
S. Khochtali ◽  
M. Sehli ◽  
S. Ben Amor ◽  
J. Feki ◽  
...  

Author(s):  
Ioannis Papasavvas ◽  
Alessandro Mantovani ◽  
Ilknur Tugal-Tutkun ◽  
Carl P. Herbort

Abstract Background Multiple evanescent white dot syndrome (MEWDS) is a rare inflammatory eye condition affecting the outer retina as a consequence of choriocapillaris non perfusion. The pathophysiology of MEWDS will be discussed based clinical appraisal and on multimodal imaging appraisal. Methods Narrative review and perspective opinion. Results Literature review results helped us to put forward (1) the specific symptomatology (decreased/blurred vision, photopsia, subjective scotomas), (2) the ill-asserted character of clinical findings (foveal granularity, white dots in fundoscopy), (3) and the crucial importance of multimodal imaging with the diagnostic triad of ICGA hypofluorescent areas, BL-FAF hyperautofluorescent areas and loss/damage of IS/OS-ellipsoid zone on SD-OCT that characterise the disease and can practically help the clinician to diagnose MEWDS. A comprehensive alternative perspective of the disease was formulated. Conclusions The bulk of evidence that we are presenting in this review, thanks to new performing non-invasive and invasive imaging modalities, is sufficiently compelling to consider MEWDS as a primary choriocapillaritis/inflammatory choriocapillaropathy. Multimodal imaging allows the clinician to diagnose MEWDS with a high level of certainty and ensures a precise follow-up.


2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Orly Gal-Or ◽  
Ethan Priel ◽  
Irit Rosenblatt ◽  
Shiri Shulman ◽  
Michal Kramer

Objective. To describe an unusual cluster of multiple evanescent white dot syndrome (MEWDS) encountered within a 3-month period. Methods. This retrospective observation study is comprised of seven patients who presented with MEWDS in a 3-month period in central Israel. Data were collected from patients’ medical records on clinical, multimodal imaging, and viral serology findings. Results. Six women and one man of mean age 31.5 ± 7.2 years. Three reported a precedent viral infection. All had unilateral decreased vision. Funduscopy revealed foveal granularity. Main Imaging Findings. Hyperfluorescent spots on blue autofluorescence (BAF), hypofluorescent spots on indocyanine green angiography, dark lesions on infrared photos, and ellipsoid zone irregularities on spectral domain optical coherence tomography (SD-OCT). Resolution of the spots on BAF correlated with anatomic (SD-OCT) and visual recovery. OCT angiography performed following the convalescence stage demonstrated intact retinal and choroidal flow. Serologic findings were inconclusive. Conclusion. We report a unique cluster of MEWDS patients presented in a short period of time. SD-OCT findings of ellipsoid zone disruption in combination with other multimodal imaging modalities are outlined meticulously. Recognizing these imaging features along with high index of clinical suspicion is important for the diagnosis of MEWDS. Serologic testing might be considered in future patients.


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