The Sensitive Fluorimetric Method for the Determination of Curcumin Using the Enhancement of Mixing Micelle

2014 ◽  
Vol 525 ◽  
pp. 89-92
Author(s):  
Wei Huang ◽  
Feng Wang ◽  
Hong Long Zhu

It is found that the fluorescence of curcumin is greatly enhanced by La3+ in the prescence of sodium dodecyl benzene sulfonate (SDBS). Based on this, a sensitive fluorimetric method for the determination of curcumin in aqueous solution is proposed. In the HOAc-NaOAc buffer, the fluorescence intensity of curcumin is proportional to the concentration of curcumin in the range of 0.0074-7.4μg·mL-1 and the detection limit is 3.66ng·mL-1. The actual samples are satisfactorily determined.

2014 ◽  
Vol 900 ◽  
pp. 297-300
Author(s):  
Feng Wang ◽  
Wei Huang ◽  
Shu Wei Wei

Curcumin (C21H20O6, CU) is a natural antioxidant, which is considered to be a very useful compound in health matters, and is employed in the treatment of cardiovascular and arthritic illnesses. It is found that the fluorescence intensity of Y3+-trpptophan (Trp) can be greatly quenched by curcumin in the presence of sodium dodecyl benzene sulfonate (SDBS). Under optimum conditions, the quenched intensity of fluorescence is in proportion to the concentration of curcumin in the range of 73.68-442.1, 0.074-5.3μg·mL-1. The detection limit (S/N=3) is 0.0185μg·mL-1. The actual samples are satisfactorily determined.


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