Detoxification Capabilities of Adsorbents for Artificial Liver Support Devices: A Comparison

2014 ◽  
Vol 936 ◽  
pp. 789-794
Author(s):  
Wei Ping Ding ◽  
Li Li Zou ◽  
Ying Ying Pei ◽  
Si Jie Sun ◽  
Da Yong Gao
Keyword(s):  
Activated Carbon ◽  
Adsorption Rate ◽  
Artificial Liver ◽  
Order Kinetic ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Anion Resin ◽  
Adsorption Technology ◽  
Liver Support Devices ◽  
Support Devices

Adsorption performances of activated carbon Norit RO 0.8, neutral resin Amberlite XAD-7, anion resin Dowex 1x4 and cation resin Dowex 50wx4 were investigated in detail for artificial liver support devices. Firstly, equilibrium adsorption experiments of these adsorbents to albumin, creatinine, bilirubin, tryptophan and cholic acid were conducted respectively. Then their adsorption capacities were obtained by curve fitting. The results indicate that activated carbon Norit RO 0.8 and anion resin Dowex 1x4 are two better adsorbents for removing toxins. Lastly, adsorption rate constants of activated carbon Norit RO 0.8 and anion resin Dowex 1x4 to all above solutes were studied with pseudo-first and second-order kinetic adsorption models. The results show that the toxin adsorption rate of anion resin Dowex 1x4 is faster than that of activated carbon Norit RO 0.8. The systematical experimental results in this paper are very important references for researchers in the field of blood purification based on adsorption technology.

ARTIFICIAL LIVER SUPPORT DEVICES FOR FULMINANT LIVER FAILURE

2001 ◽  
Vol 5 (2) ◽  
pp. 415-430 ◽  
Author(s):  
Anna Sechser ◽  
Joseph Osorio ◽  
Chris Freise ◽  
Robert W. Osorio
Keyword(s):  
Liver Failure ◽  
Artificial Liver ◽  
Fulminant Liver Failure ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Liver Support Devices ◽  
Support Devices

Developing Activated Carbon From Date Seeds and Carbon Fiber for Use in Liver Support Devices

2018 ◽  
Author(s):  
Ali Hilal-Alnaqbi ◽  
Asel Mwafy ◽  
Ameereh Seyedzadeh ◽  
Waleed Khalil Ahmed ◽  
Aisha Hilal Alnaqbi
Keyword(s):  
Activated Carbon ◽  
Carbon Fiber ◽  
Carbon Fibers ◽  
Fiber Reinforced Polymers ◽  
Carbon Fiber Reinforced Polymers ◽  
Liver Support ◽  
Reinforced Polymers ◽  
End Stage ◽  
Liver Support Devices ◽  
Support Devices

This work aims at utilizing natural resources and recycling materials from aircraft industries to enable their usage in medical and purification applications. The main application for which the materials are tested is the adsorption of bilirubin toxin from the liver of end stage liver failure patients. The two materials of concern are date seeds and carbon fiber reinforced polymers (CFRP). Samples of the materials will be treated to produce activated carbon (AC). Following the preparation of the ACs and chitosan coated ACs, tests are carried out to compare uncoated ACs with chitosan coated ACs. FTIR spectroscopy, TGA, DSC and a Spectrophotometer are utilized in order to characterize the samples obtained. From the data acquired, it is concluded that the chitosan coated ACs have better adsorption than the uncoated ACs. The activated carbon fibers showed the highest efficiency for the adsorption of bilirubin toxin. At an adsorbent dose of 0.8 gm, findings show that 98.4% of bilirubin toxin is adsorbed in samples where ACF is used as the adsorbent while 96.5% remained in samples where DPAC was used as the adsorbent.

scholarly journals 934 Artificial Liver Support in Children with Fulminant Hepatic Failure: Our Experience

2010 ◽  
Vol 68 ◽  
pp. 467-467
Author(s):  
M Corno ◽  
E Bonanomi ◽  
I Pellicioli ◽  
A Tartufari ◽  
V Corno ◽  
...  
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Artificial Liver ◽  
Liver Support ◽  
Artificial Liver Support

Artificial Liver Support -- Pipe Dream or Reality?

1994 ◽  
Vol 331 (4) ◽  
pp. 268-269 ◽  
Author(s):  
Mark S. Cattral ◽  
Gary A. Levy
Keyword(s):  
Artificial Liver ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Pipe Dream
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