scholarly journals Natural Killer Cell Group 7 Sequence in Cytotoxic Cells Optimizes Exocytosis of Lytic Granules Essential for the Perforin-Dependent, but Not Fas Ligand–Dependent, Cytolytic Pathway

2021 ◽  
Vol 5 (4) ◽  
pp. 234-245
Author(s):  
Yuhki Morikawa ◽  
Minami Murakami ◽  
Hitoshi Kondo ◽  
Noriko Nemoto ◽  
Kazuya Iwabuchi ◽  
...  
Keyword(s):  
Natural Killer Cell ◽  
Natural Killer ◽  
Fas Ligand ◽  
Killer Cell ◽  
Cell Group ◽  
Cytotoxic Cells ◽  
Lytic Granules

scholarly journals Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

PLoS Biology ◽  
2011 ◽  
Vol 9 (9) ◽  
pp. e1001152 ◽  
Author(s):  
Alice C. N. Brown ◽  
Stephane Oddos ◽  
Ian M. Dobbie ◽  
Juha-Matti Alakoskela ◽  
Richard M. Parton ◽  
...  
Keyword(s):  
Natural Killer Cell ◽  
Natural Killer ◽  
Killer Cell ◽  
Super Resolution ◽  
Cortical Actin ◽  
Lytic Granules ◽  
Immune Synapses ◽  
Super Resolution Microscopy

scholarly journals Soluble Fas ligand is associated with natural killer cell dynamics in coronary artery disease

2014 ◽  
Vol 233 (2) ◽  
pp. 616-622 ◽  
Author(s):  
Aleksander Szymanowski ◽  
Wei Li ◽  
Anna Lundberg ◽  
Chamilly Evaldsson ◽  
Lennart Nilsson ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Natural Killer Cell ◽  
Natural Killer ◽  
Fas Ligand ◽  
Killer Cell ◽  
Cell Dynamics ◽  
Soluble Fas ◽  
Soluble Fas Ligand ◽  
Artery Disease

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse

Hepatology ◽  
2012 ◽  
Vol 56 (2) ◽  
pp. 555-566 ◽  
Author(s):  
Akihito Okazaki ◽  
Nobuhiko Hiraga ◽  
Michio Imamura ◽  
C. Nelson Hayes ◽  
Masataka Tsuge ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Natural Killer Cell ◽  
Natural Killer ◽  
Fas Ligand ◽  
Killer Cell ◽  
Human Hepatocyte ◽  
Chimeric Mouse ◽  
Ligand Interaction

scholarly journals Rat Spleen Dendritic Cells Express Natural Killer Cell Receptor Protein 1 (NKR-P1) and Have Cytotoxic Activity to Select Targets via a Ca2+-dependent Mechanism

1997 ◽  
Vol 186 (3) ◽  
pp. 467-472 ◽  
Author(s):  
Régis Josien ◽  
Michèle Heslan ◽  
Jean-Paul Soulillou ◽  
Maria-Cristina Cuturi
Keyword(s):  
Dendritic Cells ◽  
Natural Killer Cell ◽  
Natural Killer ◽  
Fas Ligand ◽  
Killer Cell ◽  
Cell Receptor ◽  
Receptor Protein ◽  
Natural Killer Cell Receptor ◽  
Major Function

Dendritic cells (DC) are a subset of leukocytes whose major function is antigen presentation. We investigated the phenotype and function of enriched (95–98.5%) rat DC. We show that both spleen and thymus DC express the natural killer cell receptor protein 1 (NKR-P1) as a disulfide linked homodimer of 60 kD. Freshly isolated DC express a low level of NKR-P1, which is strongly upregulated after overnight culture. Spleen, but not thymus DC, were able to kill the NK-sensitive YAC-1 cell line in vitro, and since this killing was Ca2+ dependent, a Fas ligand–Fas interaction was probably not involved. Besides their potent antigen-presenting function, DC can thus be cytotoxic for some tumor targets.

Fas Ligand–Mediated Lethal Hepatitis After Rapid Lysis of a Localized Natural Killer Cell Lymphoma

2006 ◽  
Vol 6 (5) ◽  
pp. 417-419 ◽  
Author(s):  
David Ghez ◽  
Diane Damotte ◽  
Susan P. Perrine ◽  
Douglas V. Faller ◽  
Daniéle Canioni ◽  
...  
Keyword(s):  
Natural Killer Cell ◽  
Natural Killer ◽  
Fas Ligand ◽  
Cell Lymphoma ◽  
Killer Cell ◽  
Natural Killer Cell Lymphoma
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