Cutting Edge: Leukotriene C4 Activates Mouse Platelets in Plasma Exclusively through the Type 2 Cysteinyl Leukotriene Receptor

Hannah E. Cummings; Tao Liu; Chunli Feng; Tanya M. Laidlaw; Pamela B. Conley; Yoshihide Kanaoka; Joshua A. Boyce

doi:10.4049/jimmunol.1302187

Cutting Edge: Leukotriene C4 Activates Mouse Platelets in Plasma Exclusively through the Type 2 Cysteinyl Leukotriene Receptor

The Journal of Immunology ◽

10.4049/jimmunol.1302187 ◽

2013 ◽

Vol 191 (12) ◽

pp. 5807-5810 ◽

Cited By ~ 25

Author(s):

Hannah E. Cummings ◽

Tao Liu ◽

Chunli Feng ◽

Tanya M. Laidlaw ◽

Pamela B. Conley ◽

...

Keyword(s):

Cutting Edge ◽

Leukotriene C4 ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1203127109 ◽

2012 ◽

Vol 109 (13) ◽

pp. 4992-4997 ◽

Cited By ~ 36

Author(s):

M. K. Oyoshi ◽

R. He ◽

Y. Kanaoka ◽

A. ElKhal ◽

S. Kawamoto ◽

...

Keyword(s):

Atopic Dermatitis ◽

Mouse Model ◽

Skin Fibrosis ◽

Leukotriene C4 ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA) (responsiveness to montelukast on EIA in children)

Clinical & Experimental Allergy ◽

10.1111/j.1365-2222.2007.02795.x ◽

2007 ◽

Vol 0 (0) ◽

pp. 070831211107004-??? ◽

Cited By ~ 1

Author(s):

S.-Y. Lee ◽

H.-B. Kim ◽

J.-H. Kim ◽

B.-S. Kim ◽

M.-J. Kang ◽

...

Keyword(s):

Immunoglobulin E ◽

Bronchial Hyperresponsiveness ◽

Leukotriene C4 ◽

Korean Children ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor ◽

Exercise Induced ◽

Total Immunoglobulin ◽

Leukotriene C4 Synthase

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Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2013.03.048 ◽

2013 ◽

Vol 132 (1) ◽

pp. 205-213 ◽

Cited By ~ 242

Author(s):

Taylor A. Doherty ◽

Naseem Khorram ◽

Sean Lund ◽

Amit Kumar Mehta ◽

Michael Croft ◽

...

Keyword(s):

Cytokine Production ◽

Innate Lymphoid Cells ◽

Lymphoid Cells ◽

Cysteinyl Leukotriene ◽

Th2 Cytokine ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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Differential Signaling of Cysteinyl Leukotrienes and a Novel Cysteinyl Leukotriene Receptor 2 (CysLT2) Agonist, N-Methyl-Leukotriene C4, in Calcium Reporter and β Arrestin Assays

Molecular Pharmacology ◽

10.1124/mol.110.069054 ◽

2010 ◽

Vol 79 (2) ◽

pp. 270-278 ◽

Cited By ~ 17

Author(s):

Dong Yan ◽

Rino Stocco ◽

Nicole Sawyer ◽

Michael E. Nesheim ◽

Mark Abramovitz ◽

...

Keyword(s):

Leukotriene C4 ◽

Cysteinyl Leukotrienes ◽

Cysteinyl Leukotriene ◽

Differential Signaling ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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The cysteinyl-leukotriene receptor antagonist BAY u9773 is a competitive antagonist of leukotriene C4 in the guinea-pig ileum

European Journal of Pharmacology ◽

10.1016/s0014-2999(96)00700-5 ◽

1996 ◽

Vol 317 (1) ◽

pp. 107-113 ◽

Cited By ~ 23

Author(s):

Magnus Bäck ◽

Eva Wikström Jonsson ◽

Sven-Erik Dahlén

Keyword(s):

Guinea Pig ◽

Receptor Antagonist ◽

Leukotriene C4 ◽

Leukotriene Receptor Antagonist ◽

Guinea Pig Ileum ◽

Competitive Antagonist ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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Cysteinyl leukotriene receptor 2 (CYSLTR2; CysLT2); leukotriene C4 synthase (LTC4S)

Science-Business eXchange ◽

10.1038/scibx.2012.337 ◽

2012 ◽

Vol 5 (13) ◽

pp. 337-337

Keyword(s):

Leukotriene C4 ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor ◽

Leukotriene C4 Synthase

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Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs

European Journal of Pharmacology ◽

10.1016/j.ejphar.2015.02.014 ◽

2015 ◽

Vol 754 ◽

pp. 98-104 ◽

Cited By ~ 14

Author(s):

Yasuo Yonetomi ◽

Tomohiko Sekioka ◽

Michiaki Kadode ◽

Tetsuya Kitamine ◽

Akihiro Kamiya ◽

...

Keyword(s):

Guinea Pigs ◽

Leukotriene C4 ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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244 Evidence for Involvement of the Cysteinyl Leukotriene Receptor Type 2 (cysLTR2) in the Regulation of Food Intake and Body Weight and Possible Role for Vagal Afferents

Gastroenterology ◽

10.1016/s0016-5085(10)60202-8 ◽

2010 ◽

Vol 138 (5) ◽

pp. S-44

Author(s):

Ala'a Al-Helaili ◽

Sung Jin Park ◽

Donna M. Daly ◽

Michael Beyak

Keyword(s):

Body Weight ◽

Food Intake ◽

Vagal Afferents ◽

Receptor Type ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor

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Association study of polymorphism in leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes with phenotype of asthma and clinical parameters in Korean children

Korean Journal of Pediatrics ◽

10.3345/kjp.2009.52.6.680 ◽

2009 ◽

Vol 52 (6) ◽

pp. 680

Author(s):

Jung Yeon Shim ◽

Byung-Joo Kim ◽

Young Hwa Song ◽

Mi-Jin Kang ◽

So-Yeon Lee ◽

...

Keyword(s):

Association Study ◽

Clinical Parameters ◽

Leukotriene C4 ◽

Korean Children ◽

Cysteinyl Leukotriene ◽

Leukotriene Receptor ◽

Cysteinyl Leukotriene Receptor ◽

Leukotriene C4 Synthase

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A Selective Cysteinyl Leukotriene Receptor 2 Antagonist Blocks Myocardial Ischemia/Reperfusion Injury and Vascular Permeability in Mice

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.111.186031 ◽

2011 ◽

Vol 339 (3) ◽

pp. 768-778 ◽

Cited By ~ 40

Author(s):

Nathan C. Ni ◽

Dong Yan ◽

Laurel L. Ballantyne ◽

Alma Barajas-Espinosa ◽

Tim St. Amand ◽

...

Keyword(s):

Myocardial Ischemia ◽

Reperfusion Injury ◽

Vascular Permeability ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Cysteinyl Leukotriene ◽

Myocardial Ischemia Reperfusion Injury ◽

Leukotriene Receptor ◽

Myocardial Ischemia Reperfusion ◽

Cysteinyl Leukotriene Receptor

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