scholarly journals Diagnostic utility of conventional transbronchial needle aspiration without rapid on-site evaluation in patients with lung cancer

Lung India ◽  
2014 ◽  
Vol 31 (3) ◽  
pp. 208 ◽  
Author(s):  
Karan Madan ◽  
Anant Mohan ◽  
Deepali Jain ◽  
Vijay Hadda ◽  
GopiC Khilnani ◽  
...  
Lung India ◽  
2015 ◽  
Vol 32 (2) ◽  
pp. 198 ◽  
Author(s):  
Karan Madan ◽  
Ritika Walia ◽  
Anant Mohan ◽  
Deepali Jain ◽  
Vijay Hadda ◽  
...  

Author(s):  
Cristina Caupena ◽  
Lluis Esteban ◽  
Angels Jaen ◽  
Bienvenido Barreiro ◽  
Raquel Albero ◽  
...  

Abstract Objectives In patients with lung cancer undergoing mediastinal staging through endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), decisions are based on rapid on-site evaluation (ROSE) findings. We aimed to analyze the concordance rate between ROSE diagnosis and final diagnosis. Methods A prospective study was carried out in patients undergoing EBUS-TBNA for lung cancer staging. Diagnosis concordance was defined as cases where lymph nodes (LNs) presented the same diagnosis in ROSE and final diagnosis. Determinants of concordance were analyzed. Results Sixty-four patients were included and 637 LNs sampled. ROSE diagnosis was concordant with final diagnosis in 612 (96.1%) LNs and nonconcordant in 25 (3.9%). Differences in the concordance rate were found between pathologists, ROSE diagnoses, presence of cell block, number of passes, and number of slides. The staging status was changed between ROSE and the final diagnosis in three (4.6%) patients. Conclusions ROSE diagnosis has a high concordance with the final diagnosis.


CHEST Journal ◽  
2015 ◽  
Vol 148 (6) ◽  
pp. 1430-1437 ◽  
Author(s):  
Rocco Trisolini ◽  
Alessandra Cancellieri ◽  
Carmine Tinelli ◽  
Dario de Biase ◽  
Ilaria Valentini ◽  
...  

2017 ◽  
Vol 142 (2) ◽  
pp. 253-262 ◽  
Author(s):  
Deepali Jain ◽  
Timothy Craig Allen ◽  
Dara L. Aisner ◽  
Mary Beth Beasley ◽  
Philip T. Cagle ◽  
...  

Context.— Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a very useful tool in the field of diagnostic respiratory cytology. Rapid on-site evaluation (ROSE) of EBUS-TBNA not only has the potential to improve diagnostic yield of the procedure but also to triage samples for predictive molecular testing to guide personalized treatments for lung cancer. Objective.— To provide an overview of the current status of the literature regarding ROSE of EBUS-TBNA in the diagnosis of lung cancer. Data Sources.— An electronic literature search in PubMed and Google databases was performed using the following key words: cytology, lung cancer, on-site evaluation, rapid on-site evaluation, and ROSE EBUS-TBNA. Only articles published in English were included in this review. Conclusions.— Rapid on-site evaluation can ensure that the targeted lesion is being sampled and can enable appropriate specimen triage. If available, it should be used with EBUS-TBNA in the diagnosis of lung cancer because it can minimize repeat procedures for additional desired testing (ie, molecular studies). Some studies have shown that ROSE does not adversely affect the number of aspirations, total procedure time of EBUS-TBNA, or the rate of postprocedure complications; it is also helpful in providing a preliminary diagnosis that can reduce the number of additional invasive procedures, such as mediastinoscopy. As EBUS technology continues to evolve, our knowledge of the role of ROSE in EBUS-TBNA for the diagnosis of lung cancer will also continue to grow and evolve.


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