Quantification of plasma fibrinogen degradation products in oral submucous fibrosis: A clinicopathologic study

2007 ◽  
Vol 11 (2) ◽  
pp. 48 ◽  
Author(s):  
Suresh Barpande ◽  
SupriyaS Koshti
Keyword(s):  
Degradation Products ◽  
Oral Submucous Fibrosis ◽  
Plasma Fibrinogen ◽  
Fibrinogen Degradation Products ◽  
Clinicopathologic Study ◽  
Submucous Fibrosis

scholarly journals Plasma fibrinogen degradation products in betel nut chewers - with and without oral submucous fibrosis

2013 ◽  
Vol 17 (3) ◽  
pp. 324 ◽  
Author(s):  
G Kiran ◽  
Santosh Hunasgi ◽  
SyedAfroz Ahmed ◽  
A Krishna ◽  
MS Muni Sekhar ◽  
...  
Keyword(s):  
Degradation Products ◽  
Oral Submucous Fibrosis ◽  
Plasma Fibrinogen ◽  
Betel Nut ◽  
Fibrinogen Degradation Products ◽  
Submucous Fibrosis

Fibrinogen Fragments X, Y, D and E Increase Levels of Plasma Fibrinogen and Liver mRNAs Coding for Fibrinogen Polypeptides in Rats

1985 ◽  
Vol 53 (02) ◽  
pp. 212-215 ◽  
Author(s):  
H M G Princen ◽  
H J Moshage ◽  
J J Emeis ◽  
H J W de Haard ◽  
W Nieuwenhuizen ◽  
...  
Keyword(s):  
Regulatory Mechanism ◽  
Degradation Products ◽  
Mrna Level ◽  
Plasma Fibrinogen ◽  
Fibrin Degradation Product ◽  
Fibrinogen Degradation Products ◽  
Fibrin Degradation Products ◽  
First Time ◽  
D Dimer

SummaryPreviously, we demonstrated that in vivo regulation of liver fibrinogen synthesis occurs via the fibrinogen mRNA level. However, the molecular regulatory mechanism of fibrinogen synthesis is still not well understood. Fibrinogen or fibrin degradation products might play an important role in regulating fibrinogen synthesis. In our present study, we have injected rats intraperitoneally with purified homologous fragments and measured the liver content of mRNA specific coding for fibrinogen. Increased levels of fibrinogen mRNA and elevated plasma fibrinogen concentrations were observed in rats after administration of fibrinogen degradation products X, Y, DEGTA Dcate or E. Fragment E or E’ has a less stimulatory effect than X, Y or Dcate, whereas cross-linked fibrin degradation product D dimer does not increase fibrinogen synthesis. This article reports for the first time a stimulatory effect of the high molecular weight fibrinogen degradation products on fibrinogen synthesis.

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