scholarly journals Human Herpes Virus-8-Associated Multicentric Castleman's Disease in a Human Immunodeficiency Virus-Positive Patient with a Previous History of Kaposi's Sarcoma

2015 ◽  
Vol 5 ◽  
pp. 59 ◽  
Author(s):  
Guan Huang ◽  
Gavin Low
Keyword(s):  
Human Immunodeficiency Virus ◽  
Previous History ◽  
Castleman’S Disease ◽  
Positive Patient ◽  
Hiv Positive ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Immunodeficiency Virus ◽  
History Of

Human herpes virus-8 (HHV-8)–associated Castleman's disease (CD) is a rare non-cancerous B-cell lymphoproliferative disorder in human immunodeficiency virus (HIV)-positive patients. We report a case of HHV-8–associated CD in an HIV-positive patient with a previous history of Kaposi's sarcoma (KS). The patient presented with progressive splenomegaly and diffuse lymphadenopathy, which can be seen in multicentric CD, KS, and HIV-associated lymphoma. There are no reliable clinical or imaging features to differentiate these diseases. Lymph node biopsy confirmed HHV-8–associated CD and excluded KS and lymphoma. Due to differences in treatment options and prognosis between the three etiologies, it is important for radiologists to include HHV-8–associated CD in the differential diagnosis when encountering HIV-positive patients that present with diffuse lymphadenopathy.

Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient

2002 ◽  
Vol 116 (4) ◽  
pp. 288-290 ◽  
Author(s):  
C. V. Praveen ◽  
R. M. Terry ◽  
M. Elmahallawy ◽  
C. Horsfield
Keyword(s):  
Human Immunodeficiency Virus ◽  
Opportunistic Infection ◽  
Pneumocystis Carinii ◽  
Lymphatic Vessels ◽  
Blood Stream ◽  
Positive Patient ◽  
Hiv Positive ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Pneumocystis Carinii Infection

Pneumocystis carinii is an opportunistic infection found in patients with impaired immunity. Under favourable conditions the parasite can spread via the blood stream or lymphatic vessels and cause extrapulmonary dissemination. We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection.

scholarly journals Multicentric Castleman’s Disease, Associated with Idiopathic Thrombocytopenic Purpura

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Ruchi Sood ◽  
Harris C. Taylor ◽  
Hamed Daw
Keyword(s):  
Castleman’S Disease ◽  
Neck Mass ◽  
Current Approach ◽  
Castleman's Disease ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Neck Masses ◽  
Human Herpes Virus ◽  
Immunodeficiency Virus ◽  
Infection And Inflammation

The most common cause of a neck mass in young adults is hyperplastic lymphadenopathy consequent to infection and inflammation. Castleman’s disease (CD), an unusual benign lymphoproliferative disorder, infrequently causes neck masses. It occurs in unicentric (UCD) and multicentric (MCD) forms and is associated with human immunodeficiency virus (HIV), human herpes virus 8 (HHV-8), and Kaposi's sarcoma. We present the third known association between MCD and previous immune thrombocytopenia in the absence of HIV and HHV-8 infection and review its association with other autoimmune disorders and attendant implications for pathogenesis. Finally, we summarize the current approach to therapy.

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