Diagnostic value of a power Doppler ultrasound-based malignancy index for differentiating malignant and benign solid breast lesions

2020 ◽  
Vol 57 (1) ◽  
pp. 44
Author(s):  
SeyedBabak Moosavi Toomatari ◽  
Ali Enshaei ◽  
Afshin Mohammadi ◽  
Zahra Yekta ◽  
SeyedEhsan Moosavi Toomatari ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Power Doppler ◽  
Diagnostic Value ◽  
Breast Lesions ◽  
Power Doppler Ultrasound

3D-Power Doppler Ultrasound of Breast Lesions with a Microbubble Contrast Agent

2002 ◽  
Vol 9 (2) ◽  
pp. S384-S385 ◽  
Author(s):  
C.R Krestan ◽  
C Riedl ◽  
M Memarsadeghi ◽  
M Rudas ◽  
G Pfarl ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Doppler Ultrasound ◽  
Power Doppler ◽  
Breast Lesions ◽  
Power Doppler Ultrasound ◽  
Microbubble Contrast Agent ◽  
3D Power Doppler

Vascular morphologic information of three-dimensional power Doppler ultrasound is valuable in the classification of breast lesions

2012 ◽  
Vol 36 (4) ◽  
pp. 267-271 ◽  
Author(s):  
Ping-Lang Yen ◽  
Hwa-Koon Wu ◽  
Hsin-Shun Tseng ◽  
Shou-Jen Kuo ◽  
Yu-Len Huang ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Power Doppler ◽  
Three Dimensional ◽  
Breast Lesions ◽  
Power Doppler Ultrasound

scholarly journals Diagnostic value of 3D power Doppler ultrasound in the characterization of thyroid nodules

2019 ◽  
Author(s):  
AYŞEGÜL CANSU ◽  
EMİN AYAN ◽  
SİBEL KUL ◽  
İLKER EYÜBOĞLU ◽  
ŞÜKRÜ OĞUZ ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Thyroid Nodules ◽  
Power Doppler ◽  
Diagnostic Value ◽  
Flow Index ◽  
Power Doppler Ultrasound ◽  
Diagnostic Efficacy ◽  
3D Power Doppler ◽  
Benign Nodules

Background/aim: To evaluate the diagnostic value of vascular indices obtained using 3D power Doppler ultrasound (3DPDUS) in differentiation of benign and malignant thyroid nodules. Materials and methods: Sixty-seven patients (56 female, 11 male, mean age 44.6) with 81 thyroid nodules exhibiting mixed (peripheral and central) vascularization patterns and with the largest diameter of between 10 mm and 30 mm were prospectively evaluated using 3DPDUS. Nodule volume, vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL) software, and these indices were then compared with regard to the cyto-histopathology-based diagnosis. The optimum cutoff values for the differentiation of benign and malignant nodules were identified, and diagnostic efficacy was calculated using receiver operating characteristic (ROC) analysis. Results: Fifty-six of the 81 nodules included in this study were diagnosed as benign and 25 as malignant. Vascular indices in malignant nodules were significantly higher than those in benign nodules (p<0.05). In benign nodules, mean VI was 11.61 ± 6.88, mean FI was 39.75 ± 3.93 and VFI was 4.82 ± 2.94, compared to 18.64 ± 12.81, 41.82 ± 4.43 and 8.17 ± 6.37, respectively, in malignant nodules. The area under the curves (AUCs) were calculated as 0.68, 0.61 and 0.67 for VI, FI and VFI, respectively. At optimal cut-off values of 10.2 for VI, 40.8 for FI and 5.5 for VFI, sensitivity and specificity were 72%/55.4%, 68%/57.1% and 68%/67.9%, respectively. Conclusion: 3DPDUS could be useful in the characterization of thyroid nodules. Key words: Thyroid nodules; three-dimensional power Doppler ultrasound; vascular indices; VOCAL

The Diagnostic Value of 3D Power Doppler Ultrasound Combined With VOCAL in the Vascular Distribution of Breast Masses

2020 ◽  
Vol 27 (2) ◽  
pp. 198-203
Author(s):  
Huizhu Wang ◽  
Bing Yan ◽  
Lifang Yue ◽  
Mingyu He ◽  
Yuehua Liu ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Power Doppler ◽  
Diagnostic Value ◽  
Power Doppler Ultrasound ◽  
Breast Masses ◽  
3D Power Doppler

The Use of Doppler/Power Doppler Ultrasound and Angiography for the Evaluation of Cutaneous Perforators in the Thigh and Lumbar-Sacral Region in Pigs

2014 ◽  
Vol 30 (S 01) ◽  
Author(s):  
Radu   ◽  
Ardelean Filip ◽  
Matei Ileana ◽  
Purdoiu Cristian ◽  
Chiroiu Bogdan ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Power Doppler ◽  
Power Doppler Ultrasound ◽  
Sacral Region ◽  
Doppler Power

scholarly journals OP0178 IMAGING NEOANGIOGENESIS IN RHEUMATOID ARTHRITIS (INIRA): WHOLE-BODY SYNOVIAL UPTAKE OF A 99MTC-LABELLED RGD PEPTIDE IS HIGHLY CORRELATED WITH POWER DOPPLER ULTRASOUND

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 110.2-111
Author(s):  
L. Attipoe ◽  
S. Subesinghe ◽  
C. Blanco-Gil ◽  
M. Opena ◽  
M. Rosser ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Correlation Coefficient ◽  
Doppler Ultrasound ◽  
Imaging Modality ◽  
Power Doppler ◽  
Whole Body ◽  
Total Power ◽  
Acquisition Time ◽  
Power Doppler Ultrasound ◽  
Highly Correlated

Background:Power Doppler ultrasound (PDUS) is superior to clinical examination in detecting synovitis in patients with rheumatoid arthritis (RA). Although dynamic and cheap it is impractical to scan large numbers of joints in routine clinical settings. MRI, whilst sensitive for synovitis, is expensive and routine use is limited to targeted joints. Bone scintigraphy produces whole body images but due to limited specificity is not routinely used.99mTc-maraciclatide (Serac Healthcare) is a radiolabelled tracer which binds with high affinity to integrin αvβ3, a cell-adhesion molecule up-regulated on neoangiogenic blood vessels. It therefore has the potential to image synovial inflammation at the whole-body level. We previously showed in a pilot study that uptake was seen in the inflamed joints of five RA patients and that this correlated with PDUS. This study explores correlation with PDUS in a larger groups of patients with varied disease activity.Objectives:To determine the correlation between ultrasound and99mTc-maraciclatide imaging in patients with rheumatoid arthritis.Methods:50 patients with RA fulfilling ACR 2010 classification criteria were recruited. Patients underwent an ultrasound scan of 40 joints with grey scale (GS) and PD quantification. Each joint was scored on a scale of 0-3 for GS and PD with a total score calculated for each patient. Within 3 hours of the ultrasound patients were injected with 740 MBq of99mTc-maraciclatide. Using a gamma camera, whole body planar views and dedicated hand and foot views were taken 2 hours after injection (Figure 1). Acquisition time was 20 minutes for whole body and 20 minutes for hand and foot views.99mTc-maraciclatide images were scored as positive or negative uptake for each joint (binary score). A quantitative score was also calculated for each joint where there was uptake with this corrected for background uptake. Total binary and quantitative scores per patient were calculated.Ultrasound and99mTc-maraciclatide scores were tested for correlation with Pearson’s correlation coefficient (r). Interrater agreement for 2 scorers was calculated using kappa (ĸ) and concordance correlation coefficient (Pc).Results:Strong correlation was seen when total PDUS was compared to binary scores (r=0.92, r2=0.85) (Figure 2) and quantitative scores (r=0.85, r2=0.72). ĸ was 0.82 and 0.79 for binary and ultrasound scores respectively.Pcwas 0.82 for quantitative scores. p was <0.0005 for all results.99mTc-maraciclatide uptake was also seen in inflamed tendons/tendon sheaths. The imaging procedure was well-tolerated. There were no tracer-related adverse events.Figure 1.99mTc-maraciclatide imaging with dedicated hand and foot viewsConclusion:99mTc-maraciclatide uptake was highly correlated with PDUS highlighting its potential as an alternative imaging modality.99mTc-based planar imaging has the unique capacity to image the whole body and hence the total synovial inflammatory load in a quick acquisition. The imaging equipment to perform these scans is already widely available in radiology departments. Interpretation of scans is also much simpler compared to US/MRI. It could therefore have a role in key decision-making points in pathways for diagnosis, treatment failure, and remission prior to dose tapering.Figure 2.Correlation between total power doppler and99mTc-maraciclatide binary scoresDisclosure of Interests:None declared

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