scholarly journals Efficacy of transcutaneous electric nerve stimulation over systemic pharmacotherapy in the management of temporomandibular joint disorders – A systematic review and meta-analysis

Author(s):  
Gopal Maragathavalli ◽  
Indra Gopi ◽  
TN Uma Maheshwari
2020 ◽  
Author(s):  
Hui Ren ◽  
Jingying Liu ◽  
Yang Liu ◽  
Caiyun Yu ◽  
Guangjie Bao ◽  
...  

Abstract Background: The comparative effectiveness of low-level laser therapy (LLLT) and transcutaneous electric nerve stimulation (TENS) in the treatment of pain caused by temporomandibular joint disorders (TMD) has not been evaluated.Methods: PubMed, Cochrane Library and Embase were searched from their inception until 27 October 2019. Randomized controlled trials (RCTs) that compared the effects of LLLT or TENS or placebo group for TMD patients’ pain reduction were included. The reviewers assessed the risk of bias of individual studies with the Cochrane risk of bias tool, excluding RCTs with a high risk of bias in any domain. Then the reviewers did network meta-analysis and assessed the quality of evidence contributing to network estimate using the GRADE framework.Results: 20 RCTs with 758 patients with TMD were included. In the pair-wise meta-analysis, LLLT and TENs showed a significant pain reduction in the visual analogue scale (VAS) compared with placebo immediately after treatment [mean difference (MD)=1.99, 95% confidence interval (CI):(1.07,2.92); MD=2.16, 95%CI:(0.27,4.04), respectively]. As for pain reduction one month after treatment, LLLT performed better and there was no statistically significant difference for TENS as compared with placebo. Conclusion: The results of this meta-analysis showed the short-term efficacy of LLLT is more positive than TENS in the treatment of pain caused by temporomandibular joint disorders.


2019 ◽  
Vol 19 (2) ◽  
pp. 225-233 ◽  
Author(s):  
Justine Binny ◽  
Ngar Lok Joshua Wong ◽  
Shirali Garga ◽  
Chung-Wei Christine Lin ◽  
Chris G. Maher ◽  
...  

Abstract Background and aims There has been no comprehensive evaluation of the efficacy of transcutaneous electric nerve stimulation (TENS) for acute low back pain (LBP). The aim of this systematic review was to investigate the efficacy and safety of TENS for acute LBP. Methods We searched MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, CENTRAL, CINAHL and PsycINFO (inception to May 2018) for randomised placebo controlled trials. The primary outcome measure was pain relief in the immediate term (within 2-weeks of administration) assessed using the 100 mm visual analogue scale. A mean difference of at least 10 points on the 100-point pain scale was considered clinically significant. Methodological quality of the eligible studies was assessed using the PEDro scale and overall quality assessment rating was assessed using GRADE. Results Three placebo controlled studies (n = 192) were included. One low quality trial (n = 63) provides low quality evidence that ~30 min treatment with TENS in an emergency-care setting provides clinically worthwhile pain relief for moderate to severe acute LBP in the immediate term compared with sham TENS [Mean Difference (MD) – 28.0 (95% CI – 32.7, −23.3)]. Two other studies which administered a course of TENS over 4–5 weeks, in more usual settings provide inconclusive evidence; MD −2.75 (95% CI −11.63, 6.13). There was limited data on adverse events or long term follow-up. Conclusions The current evidence is insufficient to support or dismiss the use of TENS for acute LBP. Implications There is insufficient evidence to guide the use of TENS for acute LBP. There is low quality evidence of moderate improvements in pain with a short course of TENS (~30 min) during emergency transport of patients to the hospital. Future research should evaluate whether TENS has an opioid sparing role in the management of acute LBP.


2021 ◽  
Vol 25 (2) ◽  
pp. 441-453
Author(s):  
Lígia Figueiredo Valesan ◽  
Cecília Doebber Da-Cas ◽  
Jéssica Conti Réus ◽  
Ana Cristina Scremin Denardin ◽  
Roberto Ramos Garanhani ◽  
...  

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