scholarly journals Orthokeratinized odontogenic cyst: Report of eight cases and review of literature regarding its malignant transformation

2021 ◽  
Vol 25 (4) ◽  
pp. 11
Author(s):  
Mona Zavarei ◽  
Nazanin Mahdavi ◽  
Samira Derakhshan ◽  
MahboubeHashemi Nasab
2010 ◽  
Vol 134 (2) ◽  
pp. 271-275 ◽  
Author(s):  
Qing Dong ◽  
Shuang Pan ◽  
Li-Sha Sun ◽  
Tie-Jun Li

Abstract Context.—Orthokeratinized odontogenic cyst (OOC) is a relatively uncommon developmental cyst comprising about 10% of cases that had been previously coded as odontogenic keratocysts. Odontogenic keratocyst was designated as keratocystic odontogenic tumor (KCOT) in the new World Health Organization classification and OOC should be distinguished from KCOT for differences in histologic features and biologic behavior. Objective.—To analyze the clinicopathologic features of 61 cases of OOC in a Chinese population. Design.—Clinicopathologic analysis was performed on 61 cases of OOC. Immunohistochemical expression of Ki-67 and p63 was evaluated in 15 OOCs and 15 typical KCOTs. Results.—The 61 patients with OOC ranged from 13 to 75 years (average, 38.93 years). The lesions developed mainly in the third and fourth decades (57.38%) with a distinct predilection for males (72.13%). Six (9.84%) lesions were found in the maxilla and 55 (90.16%) in the mandible. The most common sites were in the mandibular molar and ramus region. Of the 54 cases with radiographic record, 47 (87.04%) were unilocular and 7 (12.96%) were multilocular radiolucencies. Twenty-seven of the 54 cysts were associated with an impacted tooth. Follow-up of 42 patients revealed no recurrence during an average period of 76.8 months after surgery. Compared with KCOTs, expression level of Ki-67 and p63 was significantly lower in OOCs, suggesting a lower proliferative activity. Conclusion.—Orthokeratinized odontogenic cyst is clinicopathologically distinct from KCOT and should constitute its own clinical entity.


Author(s):  
Anshi Jain ◽  
DeviCharan Shetty ◽  
AjitSingh Rathore ◽  
Natasha Thokchom ◽  
Neha Khurana

Author(s):  
Ana Maria Lucas Guimarães ◽  
Patrícia Vitor De Souza ◽  
Ana Carolina Uchoa Vasconcelos ◽  
Sandra Beatriz Chaves Tarquinio ◽  
Adriana Etges ◽  
...  

2014 ◽  
Vol 5 (4) ◽  
pp. 287 ◽  
Author(s):  
Ramakrishnan Bharathi ◽  
Parthiban Nallaiyan ◽  
Gnanadeepam Santiago

2017 ◽  
Vol 65 (2) ◽  
pp. 418 ◽  
Author(s):  
S Narla ◽  
J Govindraj ◽  
K Chandrasekar ◽  
P Sushama

2015 ◽  
Vol 6 (2) ◽  
pp. 40-43 ◽  
Author(s):  
Subhadeep Sarkar ◽  
Obaid Khursheed ◽  
Ruby Bansal ◽  
Waseem K Burza

2020 ◽  
Vol 6 (2) ◽  
pp. 100153
Author(s):  
Dina Amin ◽  
Kelly R. Magliocca ◽  
Shelly Abramowicz

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