Anticoagulation in a pregnant patient with mechanical heart valves: Case reports and literature review

2020 ◽  
Vol 17 (1) ◽  
pp. 76
Author(s):  
MZ Usman ◽  
SA Isezuo ◽  
H Umar ◽  
MA Ndakotsu
2011 ◽  
Vol 2 (1S) ◽  
pp. 115
Author(s):  
Marco Marietta ◽  
Paola Pedrazzi ◽  
Alessandro Ghiddi

Whether to resume the anticoagulant or the antiaggregant therapy after an episode of major haemorrhage is a difficult dilemma for the physician. The physician has to take into consideration two major questions: whether the benefits of restarting anticoagulation outweigh the risk, and if so, when and how should anticoagulation be restarted. Although some case reports suggest that anticoagulation can be withheld safely for short periods after ICH, even in patients with mechanical heart valves, it is still not clear if long-term anticoagulation can be safely reinstituted after haemorrhage, for example in patients with atrial fibrillation. In fact, no large and well-conducted randomised clinical trials are available, and there is lack of strong evidence on which guidelines recommendations can be based. The article summarise the available literature findings. Finally, a protocol is suggested which may represent a useful tool for assessing treatment options.


2001 ◽  
Vol 72 (6) ◽  
pp. 2051-2054 ◽  
Author(s):  
William B Tisol ◽  
Dale K Mueller ◽  
Frederick B Hoy ◽  
Robert C Gomez ◽  
Barry S Clemson ◽  
...  

2011 ◽  
Vol 2 (1S) ◽  
pp. 115-120
Author(s):  
Marco Marietta ◽  
Paola Pedrazzi ◽  
Alessandro Ghiddi

Whether to resume the anticoagulant or the antiaggregant therapy after an episode of major haemorrhage is a difficult dilemma for the physician. The physician has to take into consideration two major questions: whether the benefits of restarting anticoagulation outweigh the risk, and if so, when and how should anticoagulation be restarted. Although some case reports suggest that anticoagulation can be withheld safely for short periods after ICH, even in patients with mechanical heart valves, it is still not clear if long-term anticoagulation can be safely reinstituted after haemorrhage, for example in patients with atrial fibrillation. In fact, no large and well-conducted randomised clinical trials are available, and there is lack of strong evidence on which guidelines recommendations can be based. The article summarise the available literature findings. Finally, a protocol is suggested which may represent a useful tool for assessing treatment options.


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