The value of adding ketamine to lidocaine and bupivacaine mixture in ultrasonic-guided spermatic cord block in scrotal surgery: a randomized double-blind prospective study

2018 ◽  
Vol 46 (1) ◽  
pp. 23
Author(s):  
MostafaM Shaheen ◽  
NadiaH Fattouh ◽  
AymanA Yousef ◽  
AhmedA Shama
1994 ◽  
Vol 12 (1) ◽  
pp. 155-158 ◽  
Author(s):  
R M Goldberg ◽  
C L Loprinzi ◽  
J R O'Fallon ◽  
M H Veeder ◽  
A W Miser ◽  
...  

PURPOSE To determine the efficacy of transdermal clonidine for alleviating tamoxifen-induced hot flashes in women with a history of breast cancer. PATIENTS AND METHODS A randomized, double-blind, crossover design was used in this prospective study. Women with a history of breast cancer who were receiving tamoxifen and suffering from hot flashes were potentially eligible for this protocol study. RESULTS Clonidine did reduce hot-flash frequency to a degree that was statistically impressive (P < .0001), but clinically moderate (20% reduction from baseline). It also decreased hot-flash severity (P = .02, 10% reduction from baseline). Clonidine was related to increased mouth dryness (P < .001), constipation (P < .02), itchiness under the patch (P < .01), and drowsiness (P < .05). CONCLUSION Better means are needed to alleviate hot flashes among patients in whom estrogen therapy is contraindicated.


Sign in / Sign up

Export Citation Format

Share Document