Experimental and computational study of mechanical and transport properties of a polymer coating for drug-eluting stents

2015 ◽  
Vol 6 (11) ◽  
pp. 1255-1268 ◽  
Author(s):  
Mariacristina Gagliardi
Keyword(s):  
Transport Properties ◽  
Polymer Coating ◽  
Computational Study ◽  
Drug Eluting Stents ◽  
Drug Eluting

Nano- and Micro-Scale Adhesion in Drug-eluting Stents

2009 ◽  
Vol 1239 ◽  
Author(s):  
Ting Tan ◽  
Juan Meng ◽  
Nima Rahbar ◽  
Hannah Li ◽  
George Papandreou ◽  
...  
Keyword(s):  
Fracture Toughness ◽  
Computational Study ◽  
Interfacial Fracture ◽  
Drug Eluting Stents ◽  
Pure Mode ◽  
Force Microscopy ◽  
Atomic Force ◽  
Drug Eluting ◽  
Model Drug ◽  
Mechanics Concepts

AbstractThis paper presents a combined experimental and theoretical/computational study of adhesion and interfacial fracture between multilayers in a CYPHER® model drug eluting stents (DES). Atomic Force Microscopy (AFM) is used to obtain pull-off forces between coated AFM tips and substrates that simulate the bimaterial surfaces in the DES. Adhesion theories and fracture mechanics concepts are then applied to obtain estimates of the fracture toughness over a range of mode mixities between pure mode I and pure mode II. The trends in the estimates are shown to be in good agreement with experimental measurements of interfacial fracture toughness obtained from Brazil disk specimens over the same range of mode mixities.

scholarly journals Comparative clinical performance of two types of drug-eluting stents with abluminal biodegradable polymer coating: Five-year results of the DESTINY randomized trial

2021 ◽  
Vol 40 (2) ◽  
pp. 71-76
Author(s):  
Guy F.A. Prado Jr ◽  
Alexandre A.C. Abizaid ◽  
George C. Meireles ◽  
Rogério Sarmento-Leite ◽  
Mauricio Prudente ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Biodegradable Polymer ◽  
Polymer Coating ◽  
Clinical Performance ◽  
Drug Eluting Stents ◽  
Drug Eluting

Drug-Eluting Stents Equal on Thrombosis

2012 ◽  
Vol 45 (14) ◽  
pp. 8
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Drug Eluting Stents ◽  
Drug Eluting
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