Production of Antitumor Antibiotic GKK1032B by Penicillium citrinum, an Endophytic Fungus Isolated from Garcinia mangostana Fruits

Two new compounds, named ( Z)-7,4′-dimethoxy-6-hydroxyaurone-4- O-β-glucopyranoside (1) and (-)-4- O-(4- O-β-D-glucopyranosylcaffeoyl)quinic acid (2), were isolated from the endophytic fungus Penicillium citrinum of Avicennia marina. Their structures were elucidated on the basis of spectroscopic analysis. Additionally, compound 2 exhibited potent chemoreversal activity, mainly by inhibiting P-glycoprotein efflux pump function.

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Pencitrin and pencitrinol, two new citrinin derivatives from an endophytic fungus Penicillium citrinum salicorn 46

Phytochemistry Letters ◽

10.1016/j.phytol.2017.10.003 ◽

2017 ◽

Vol 22 ◽

pp. 229-234 ◽

Cited By ~ 7

Author(s):

Yimin Hu ◽

Junnan Zhang ◽

Dong Liu ◽

Jia Guo ◽

Tianxing Liu ◽

...

Keyword(s):

Endophytic Fungus ◽

Penicillium Citrinum

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Secondary Metabolites from the Endophytic Fungus Penicillium citrinum

Chemistry of Natural Compounds ◽

10.1007/s10600-016-1622-7 ◽

2016 ◽

Vol 52 (2) ◽

pp. 304-305

Author(s):

Hongqi Zhang ◽

Zhangshuang Deng ◽

Dan Luo ◽

Zhiyong Guo ◽

Yan Peng ◽

...

Keyword(s):

Secondary Metabolites ◽

Endophytic Fungus ◽

Penicillium Citrinum

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Neuroprotective metabolites from the endophytic fungus Penicillium citrinum of the mangrove Bruguiera gymnorrhiza

Phytochemistry Letters ◽

10.1016/j.phytol.2015.03.007 ◽

2015 ◽

Vol 12 ◽

pp. 148-152 ◽

Cited By ~ 16

Author(s):

Yan-Zhi Wu ◽

Fang Qiao ◽

Guo-Wei Xu ◽

Jie Zhao ◽

Jun-Fang Teng ◽

...

Keyword(s):

Endophytic Fungus ◽

Penicillium Citrinum ◽

Bruguiera Gymnorrhiza

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A New Metabolite from the Endophytic Fungus Penicillium citrinum

Natural Product Communications ◽

10.1177/1934578x1300800510 ◽

2013 ◽

Vol 8 (5) ◽

pp. 1934578X1300800 ◽

Cited By ~ 1

Author(s):

Xinlan Li ◽

Liang Zhang ◽

Yanhui Liu ◽

Zhiyong Guo ◽

Zhangshuang Deng ◽

...

Keyword(s):

Cytotoxic Activity ◽

Cell Lines ◽

Cancer Cell ◽

Endophytic Fungus ◽

Cancer Cell Lines ◽

Penicillium Citrinum ◽

Hep G2 ◽

Different Levels

A new polyketide, penicillocitrin A (1), together with four known compounds, was isolated from the endophytic fungus Penicillium citrinum (CTGU-TS-24) of Tapiscia sinensis Oliv., and their structures were elucidated by NMR spectroscopic and MS spectrums. The five compounds were evaluated cytotoxic activity to four cancer cell lines A549, Hep G2, Hela and Caski at different levels.

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