scholarly journals Structural chromosomal abnormalities in couples in cases of recurrent spontaneous abortions in Jilin Province, China

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
H.-T. Fan ◽  
M. Zhang ◽  
P. Zhan ◽  
X. Yang ◽  
W.-J. Tian ◽  
...  
Keyword(s):  
Chromosomal Abnormalities ◽  
Jilin Province ◽  
Spontaneous Abortions ◽  
Recurrent Spontaneous Abortions

scholarly journals Chromosomal abnormalities in recurrent spontaneous abortions: A retrospective study

2020 ◽  
Author(s):  
Inusha Panigrahi ◽  
Mohd. Shariq ◽  
Ravi Thakur ◽  
Subhas Saha ◽  
Gurjit Kaur
Keyword(s):  
Chromosomal Rearrangement ◽  
Chromosomal Abnormalities ◽  
Chromosomal Rearrangements ◽  
First Trimester ◽  
Median Number ◽  
Chromosomal Anomalies ◽  
Spontaneous Abortions ◽  
Reciprocal Translocations ◽  
Recurrent Spontaneous Abortions ◽  
Complex Chromosomal Rearrangement

Purpose: Evaluation of recurrent spontaneous abortions (RSA) can be challenging for a Obstetrician. In case of early first trimester abortions, chromosomal abnormalities can be identified as an important cause. We analysed the RSA cases followed up and diagnosed in the Genetic Clinic or Genetic Lab of 2 hospitals in the region. Methods: Those couples with 3 or more spontaneous abortions were included in the analysis. Karyotyping was one using standard protocol with G-banding and reporting as per ISCN guidelines. Results: Of 97 RSA couples, 20 showed chromosomal abnormalities, and 15 of these had balanced chromosomal rearrangements. The age ranged from 22 years to 37 years, and the median number of abortions was 4. Complex chromosomal rearrangement was seen in 2 couples, in one partner. The spectrum of chromosomal anomalies in couples with RSA is discussed here. Conclusions: Frequency of chromosomal abnormalities in RSA was higher in present study compared to previous studies. Reciprocal translocations were commonest abnormality.

Immunogenetic and serological investigations in nonpregnant and in pregnant women with a history of recurrent spontaneous abortions

1994 ◽  
Vol 27 (2) ◽  
pp. 95-109 ◽  
Author(s):  
Gertrud Mueller-Eckhardt ◽  
Peter Mallmann ◽  
Jürgen Neppert ◽  
Annette Lattermann ◽  
Anette Melk ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Spontaneous Abortions ◽  
Recurrent Spontaneous Abortions ◽  
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