First-in-man use of a novel embolic protection device for patients undergoing transcatheter aortic valve implantation

2012 ◽  
Vol 8 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Christoph K. Naber ◽  
Alexander Ghanem ◽  
Alexander A. Abizaid ◽  
Alexander Wolf ◽  
Jan-Malte Sinning ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Protection Device ◽  
Embolic Protection Device ◽  
Embolic Protection ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Filter-based cerebral embolic protection with transcatheter aortic valve implantation: the randomised MISTRAL-C trial

2016 ◽  
Vol 12 (4) ◽  
pp. 499-507 ◽  
Author(s):  
Nicolas M. Van Mieghem ◽  
Lennart van Gils ◽  
Habib Ahmad ◽  
Floortje van Kesteren ◽  
Hendrik W. van der Werf ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Embolic Protection ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

scholarly journals Cerebral Embolic Protection in TAVI: Friend or Foe

2019 ◽  
Vol 14 (1) ◽  
pp. 22-25 ◽  
Author(s):  
Michael Teitelbaum ◽  
Rafail A Kotronias ◽  
Luciano A Sposato ◽  
Rodrigo Bagur
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Diffusion Weighted Mri ◽  
Cerebrovascular Accidents ◽  
Embolic Protection ◽  
Transcatheter Aortic Valve ◽  
Ischaemic Attack ◽  
Protection Devices ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Cerebrovascular accidents including stroke or transient ischaemic attack are one of the most feared complications after transcatheter aortic valve implantation. Transcatheter aortic valve implantation procedures have been consistently associated with silent ischaemic cerebral embolism as assessed by diffusion-weighted MRI. To reduce the risk of cerebrovascular accidents and silent emboli, cerebral embolic protection devices were developed with the aim of preventing procedural debris reaching the cerebral vasculature. The authors summarise the available data regarding cerebral embolic protection devices and its clinical significance.

scholarly journals Need for Embolic Protection During Transcatheter Aortic Valve Implantation: An Interventionalist’s Perspective on Histopathology Findings

2017 ◽  
Vol 12 (01) ◽  
pp. 36 ◽  
Author(s):  
Herbert G Kroon ◽  
Nicolas MDA Van Mieghem ◽  
◽  
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Severe Aortic Stenosis ◽  
Current Evidence ◽  
Embolic Protection ◽  
Transcatheter Aortic Valve ◽  
Replacement Technique ◽  
Protection Devices ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Transcatheter aortic valve implantation (TAVI) is a less invasive aortic valve replacement technique and is indicated for patients with symptomatic severe aortic stenosis and a high operative risk. Cerebral embolisation seems inherent to TAVI, as illustrated by the consistent appearance of new brain lesions on post-procedural MRI studies. Embolic protection devices may capture or deflect embolised material en route to the brain and thus reduce TAVI-related brain injury. Histopathology studies of captured debris revealed a diverse aetiology including recent or organised thrombotic material, tissue originating from the aortic valve, atherosclerotic plaques or myocardium and foreign body components. In this overview we provide a perspective on current evidence and implications for embolic protection devices in the dynamic TAVI field.

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