Antifilarial Activity of Levamisole Hydrochloride Against Subperiodic Brugia Malayi Infection of Domestic Cats

1974 ◽  
Vol 23 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Mak Joon-Wah ◽  
S. Sivanandam ◽  
V. Zaman
Keyword(s):  
Brugia Malayi ◽  
Domestic Cats ◽  
Antifilarial Activity

Improved antifilarial activity of ivermectin in chitosan–alginate nanoparticles against human lymphatic filarial parasite, Brugia malayi

2013 ◽  
Vol 112 (8) ◽  
pp. 2933-2943 ◽  
Author(s):  
Mohammad Ali ◽  
Mohammad Afzal ◽  
Meenakshi Verma ◽  
Shailja Misra-Bhattacharya ◽  
Farhan Jalees Ahmad ◽  
...  
Keyword(s):  
Brugia Malayi ◽  
Filarial Parasite ◽  
Antifilarial Activity

Antifilarial activity of Zoanthus species (Phylum Coelenterata, Class Anthzoa) against human lymphatic filaria, Brugia malayi

2004 ◽  
Vol 93 (4) ◽  
Author(s):  
V. Lakshmi ◽  
A. Saxena ◽  
K. Pandey ◽  
Preeti Bajpai ◽  
Shailja Misra-Bhattacharya
Keyword(s):  
Brugia Malayi ◽  
Antifilarial Activity

scholarly journals Corrigendum to “Therapeutic efficacy of doxycycline in domestic cats naturally infected with Brugia malayi in field condition” [Exp. Parasitol. (2019) 73–78/200]

2022 ◽  
pp. 108207
Author(s):  
Hathai Nochot ◽  
Sumat Loimek ◽  
Patcharin Priyavoravong ◽  
Sirichit Wongkamchai ◽  
Patsharaporn Techasintana Sarasombath
Keyword(s):  
Field Condition ◽  
Therapeutic Efficacy ◽  
Brugia Malayi ◽  
Domestic Cats

Antifilarial activity of intravenous suramin and oral diethylcarbamazine citrate on subperiodic Brugia malayi in the leaf-monkey, Presbytis cristata

1990 ◽  
Vol 64 (2) ◽  
pp. 96-99 ◽  
Author(s):  
J. W. Mak ◽  
P. L. W. Lam ◽  
M. F. Choong ◽  
K. Suresh
Keyword(s):  
Adult Worm ◽  
Brugia Malayi ◽  
Post Treatment ◽  
Primate Model ◽  
Leaf Monkey ◽  
Diethylcarbamazine Citrate ◽  
Worm Recovery ◽  
Antifilarial Activity ◽  
Human Primate

ABSTRACTThe known filaricides, suramin and diethylcarbamazine citrate, were tested against subperiodic Brugia malayi infection in the leaf-monkey, Presbytis cristata. As expected, intravenous suramin at 10 mg/kg daily × 5 days or 17 mg/kg weekly × 5 weeks, did not show any microfilaricidal activity, but substantially reduced the recovery of live adult worms to 50·6% and 13·6% of controls respectively. Oral diethylcarbamazine citrate at 6 mg/kg daily × 6 or 10 days reduced final microfilarial counts to 30% of initial counts four weeks post-treatment and adult worm recovery was reduced to 4·5% and 0% of controls respectively. Although the antifilarial activity of these drugs against the infection in this non-human primate model appears to be similar to that seen in man, these results have to be confirmed using larger groups of animals.

scholarly journals Antifilarial Activity of Eucalyptus globulus Labill. Leaves Against Brugia malayi

2016 ◽  
Vol 19 (1) ◽  
pp. 44-47 ◽  
Author(s):  
Vijai Lakshmi ◽  
Shailja Misra Bhattacharya
Keyword(s):  
Brugia Malayi ◽  
Ethanolic Extract ◽  
Pharmaceutical Journal ◽  
Oral Route ◽  
Meriones Unguiculatus ◽  
Filarial Parasite ◽  
Mastomys Coucha ◽  
Antifilarial Activity

The present study is aimed to evaluate the antifilarial activity of Eucalyptus globules Labill. (Myrtaceae) against human lymphatic filarial parasite Brugia malayi in vitro and in vivo. The ethanolic extract of the leaves was tested in vitro on adult worms and microfilariae (mf) of B. malayi and the active sample was further evaluated in vivo in B. malayi intraperitoneally (i.p.) transplanted in the jird model (Meriones unguiculatus) and Mastomys coucha subcutaneously infected with infective larvae (L3). The ethanolic extract of the leaves of the E. globulus was tested in vitro on adult worms and microfilariae (mf) of B. malayi and the active sample was further evaluated in vivo in B. malayi. The ethanolic extract was active in vitro (IC50: adult = 62.5 ?g/ml; mf = 31.2. ?g/ml) where it demonstrated 66.7% adulticidal and embryostatic effect on B. malayi in Mastomys at a dose of 5 × 100 mg/kg by oral route. The antifilarial test conducted was at 5 × 100 mg/kg by subcutaneous route revealed excellent adulticidal efficacy resulting in to the death of 66.7% transplanted adult B. malayi in the peritoneal cavity of jirds in addition to noticeable microfilaricidal action on the day of autopsy. The findings revealed that the extract from the leaves of E. globulus contains promising in vitro and in vivo antifilarial activity against human lymphatic filarial parasite B. malayi which may be further explored to new antifilarial agents.Bangladesh Pharmaceutical Journal 19(1): 44-47, 2016

Therapeutic efficacy of doxycycline in domestic cats naturally infected with Brugia malayi in field condition

2019 ◽  
Vol 200 ◽  
pp. 73-78 ◽  
Author(s):  
Hathai Nochot ◽  
Sumat Loimek ◽  
Patcharin Priyavoravong ◽  
Sirichit Wongkamchai ◽  
Patsharaporn Techasintana Sarasombath
Keyword(s):  
Field Condition ◽  
Therapeutic Efficacy ◽  
Brugia Malayi ◽  
Domestic Cats

Antifilarial activity of marine sponge Haliclona oculata against experimental Brugia malayi infection

2012 ◽  
Vol 130 (4) ◽  
pp. 449-455 ◽  
Author(s):  
Jyoti Gupta ◽  
Sweta Misra ◽  
Sunil Kumar Mishra ◽  
Shishir Srivastava ◽  
M.N. Srivastava ◽  
...  
Keyword(s):  
Marine Sponge ◽  
Brugia Malayi ◽  
Haliclona Oculata ◽  
Antifilarial Activity

PCR based method for identification of zoonostic Brugia malayi microfilariae in domestic cats

2002 ◽  
Vol 16 (2) ◽  
pp. 129-135 ◽  
Author(s):  
K. Chansiri ◽  
T. Tejangkura ◽  
P. Kwaosak ◽  
N. Sarataphan ◽  
S. Phantana ◽  
...  
Keyword(s):  
Brugia Malayi ◽  
Domestic Cats
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