scholarly journals Evaluation of the Reliability of Preoperative Ultrasonography and Ultrasonography-guided Fine Needle Aspiration Biopsy in Axillary Staging in Patients With Breast Cancer

2021 ◽  
Vol 11 (3) ◽  
pp. 269-276
Author(s):  
Emine Yıldırım ◽  
Zekeriya Pelen ◽  
Murat Keğin ◽  
Neşe Uçar ◽  
Yasemin Kayadibi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Axillary Staging ◽  
Fine Needle ◽  
Preoperative Ultrasonography ◽  
Needle Aspiration Biopsy

scholarly journals Developing a Breast Fine Needle Aspiration Biopsy Service in Peru

2016 ◽  
Vol 2 (3_suppl) ◽  
pp. 16s-16s
Author(s):  
Dianna Ng ◽  
Britt-Marie Ljung ◽  
Ricardo Bardales ◽  
Milagros Abad ◽  
Manuel Cedano ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Phase 1 ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Phase 2 ◽  
Cancer Society ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Abstract 6 Background: Breast cancer incidence is increasing in developing countries. In 2010, 57.8% of breast cancers in Peru were at least stage III at diagnosis. Federal and regional Peruvian institutions partnered with several organizations, including UCSF, to improve access and quality of breast cancer care in Peru. Phase 1 involved screening with clinical breast exam, creating a community-based referral system for women with masses, and promoting evaluation of lesions using fine needle aspiration biopsy (FNAB) by trained physicians, with treatment at the regional cancer institute. Curricula for each activity were developed and validated. During phase 1, in-country FNAB expertise was recognized as limited. For phase 2, the critical objective was to solidify local capacity for high-quality FNAB and integrate FNAB into standard of care for breast cancer. Methods: Three main activities were completed during phase 2. 1) Develop a Training of Trainers (ToT) curriculum for FNAB, and identify master trainers and trainees. 2) Facilitate endorsement of a national approach to training FNAB and undertake preliminary rollout in La Libertad region. 3) Strengthen interpretation and reporting of FNAB results. Results: A 5-day ToT pilot course occurred during October 19-23, 2014. Prior to the course, women with palpable masses were identified during a breast screening campaign and scheduled for FNAB. Regional, national and international clinical teams observed, procured and interpreted FNAB. Four new cases of cancer and eight cases of granulomatous mastitis were diagnosed. Slide quality before and after the training intervention will be compared. Following the course, a one-day validation meeting including physicians and national leaders took place at the national cancer center in Lima, Peru. FNAB was endorsed for early diagnosis and triage. Conclusions: To ensure sustainability of FNAB, cytology fellowships and training centers are needed. Strengthening partnerships will be critical for long-term capacity. An electronic reporting system will be developed to replace paper-based methods. Funding: Norwegian Cancer Society/Norwegian Breast Cancer Society (NCS/NBCS), Susan G. Komen for the Cure, The PATH Catalyst Fund. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST: No COIs from the authors.

scholarly journals Reliability of fine needle aspiration biopsy in diagnosis of breast lump

2019 ◽  
Vol 15 (1) ◽  
pp. 61-67
Author(s):  
Sarab K. Abedalrahman
Keyword(s):  
Breast Cancer ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
False Negative ◽  
Screening Method ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Breast Lump ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Background: breast cancer is commonest cancer globally and the 1st cancer in Iraq among females, its management and prognosis depend on early diagnosis, the traditional method was excisional biopsy which is expensive and invasive leading to delayed diagnosis, FNAB is cheap nom invasive more acceptable to women, Aim of the study: to test the reliability of FNAB in preoperative diagnosis of breast lump. Methodology: This is a retrospective study of 204 cases, 102 breast cancer cases and 102 benign breast lesions, taken between Jan. 2017 – Nov. 2017. The sample taken from the breast cancer early detection center in  Al-Alwiyaa maternity teaching hospital, during the year 2017 Results: Invasive ductal carcinoma (IDC) was found among  82(80.4%) of malignant cases, ILC was 14(13.7%) , fibroadenoma was the most common  benign lesions 51(50%), The absolute sensitivity was 96% , specificity 100%, with 4% false negative the accuracy was 98%. The complete sensitivity was 96%, and specificity was 83%, with 4% false negative and 17% false positive cases, the accuracy was 90%, Conclusion and recommendation: fine-needle aspiration biopsy (FNAB) is accurate for breast lump diagnosis. With high sensitivity and specificity. FNAB is a good screening method and help in an improvement of treatment planning

scholarly journals Evaluating Estrogen Receptor Immunohistochemistry on Cell Blocks From Breast Cancer Patients in a Low-Resource Setting

2020 ◽  
Author(s):  
Asteria H. Kimambo ◽  
Edda A. Vuhahula ◽  
Amos R. Mwakigonja ◽  
Britt-Marie Ljung ◽  
Li Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Cell Block ◽  
Fine Needle ◽  
Resource Setting ◽  
Needle Aspiration Biopsy

Context.— Breast cancer biomarker assessment is critical in determining treatment and prognosis. In Tanzania, immunohistochemistry (IHC) is limited to surgical specimens and core biopsies. However, performing IHC on fine-needle aspiration biopsy cell blocks would offer numerous advantages. Objective.— To compare the performance between estrogen receptor (ER) IHC performed at Muhimbili National Hospital (MNH) in Tanzania and ER IHC performed at University of California, San Francisco (UCSF), to demonstrate feasibility of performing IHC using cell blocks in Tanzania. Design.— Patients with breast masses were recruited prospectively from the fine-needle aspiration biopsy clinic at MNH. Estrogen receptor IHC results on cell blocks, performed at both MNH and UCSF, and corresponding tissue blocks, performed at MNH, were compared to determine concordance. Results.— Eighty-six cell blocks were evaluated by ER IHC at MNH, with 41 of 86 (47.7%) positive and 45 of 86 (52.3%) negative. Among 65 UCSF and MNH cell block pairs, overall ER IHC concordance was 93.8% (61 of 65) and positive concordance was 93.5% (29 of 31) (κ = 0.88, P > .99). Among 43 paired UCSF cell blocks and MNH tissue blocks, overall ER IHC concordance was 88.3% (38 of 43) and positive concordance was 90.5% (19 of 21) (κ = 0.77, P > .99). We compared 62 MNH cell block and tissue block pairs. Overall ER IHC concordance was 90.3% and positive concordance was 87.9% (κ = 0.81, P = .69). Conclusions.— Pairwise comparisons between ER IHC at MNH, on cell blocks and tissue blocks, with ER IHC at UCSF on cell blocks showed excellent concordance. We demonstrate that ER IHC on fine-needle aspiration biopsy specimens can be implemented in resource-constrained settings.

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