scholarly journals The Role of Metabolic Volumetric Parameters in Predicting Malignancy in Incidental Thyroid Nodules Detected in 18F-FDG PET/CT Scans

2021 ◽  
Vol 30 (2) ◽  
pp. 86-92
Author(s):  
Mehmet Erdoğan ◽  
Hakan Korkmaz ◽  
Bora Torus ◽  
Mustafa Avcı ◽  
Şerife Mehtap Boylubay ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Ct Scans ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Hounsfield unit value has null effect on thyroid nodules at 18F-FDG PET/CT scans

2018 ◽  
Vol 62 (4) ◽  
pp. 460-465
Author(s):  
Filiz Eksi Haydardedeoglu ◽  
Gulay Simsek Bagir ◽  
Nese Torun ◽  
Emrah Kocer ◽  
Mehmet Reyhan ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Hounsfield Unit ◽  
Ct Scans ◽  
Null Effect ◽  
Unit Value ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals The role of histogram analysis of grayscale sonograms to differentiate thyroid nodules identified by 18F-FDG PET-CT

Medicine ◽  
2020 ◽  
Vol 99 (48) ◽  
pp. e23252
Author(s):  
Ko Woon Park ◽  
Jung Hee Shin ◽  
Soo Yeon Hahn ◽  
Jae-Hun Kim ◽  
Yaeji Lim ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Histogram Analysis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Thyroid nodules with indeterminate cytology: prospective comparison between 18F-FDG-PET/CT, multiparametric neck ultrasonography, 99mTc-MIBI scintigraphy and histology

2016 ◽  
Vol 174 (5) ◽  
pp. 693-703 ◽  
Author(s):  
A Piccardo ◽  
M Puntoni ◽  
G Treglia ◽  
L Foppiani ◽  
F Bertagna ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Univariate Analysis ◽  
Prospective Comparison ◽  
Positron Emission ◽  
Pet Ct ◽  
99Mtc Mibi ◽  
Indeterminate Cytology ◽  
Fdg Pet Ct

Purpose To evaluate the role of 18F-flurodeoxiglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in predicting malignancy of thyroid nodules with indeterminate cytology. Patients and methods We analysed 87 patients who have been scheduled to undergo surgery for thyroid nodule with indeterminate cytology. All patients underwent 18F-FDG-PET/CT, multiparametric neck ultrasonography (MPUS), and 99mTc-methoxyisobutylisonitrile scintigraphy (99mTc-MIBI-scan). Histopathology was the standard of reference. We compared the sensitivity (SE), specificity (SP), accuracy (AC), positive (PPV) and negative predictive (NPV) values of 18F-FDG-PET/CT with those of 99mTc-MIBI-scan and MPUS in detecting cancer. Univariate and multivariate analyses evaluated the association between each diagnostic tool and histopathology. Results On histopathology, 69 out of 87 nodules were found to be benign and 18 to be malignant. The SE, SP, AC, PPV and NPV of 18F-FDG-PET/CT were 94, 58, 66, 37 and 98% respectively. The SE, AC and NPV of 18F-FDG-PET/CT were significantly higher than those of MPUS and 99mTc-MIBI-scan. The association of both positive 18F-FDG-PET/CT and MPUS (FDG+/MPUS+) showed significantly lower SE (61% vs 94%) and NPV (88% vs 98%) than 18F-FDG-PET/CT alone, but significantly higher SP (77% vs 58%). On univariate analysis, 18F-FDG-PET/CT and the combination of FDG+/MPUS+ and of FDG+/MIBI− were all significantly associated with histopathology. On multivariate analysis, only FDG+/MIBI− was significantly associated with histopathology. Conclusion The AC of 18F-FDG-PET /CT in detecting thyroid malignancy is higher than that of 99mTc-MIBI-scan and MPUS. A negative 18F-FDG-PET/CT correctly predicts benign findings on histopathology. The association of FDG+/MPS+ is significantly more specific than 18F-FDG-PET/CT alone in identifying differentiated thyroid cancer. A positive 18F-FDG-PET/CT is significantly associated with malignancy when qualitative 99mTc-MIBI-scan is rated as negative.

Indeterminate thyroid nodules. The role of 18F-FDG PET/CT in the “era” of ultrasonography risk stratification systems and new thyroid cytology classifications

Endocrine ◽  
2020 ◽  
Vol 69 (3) ◽  
pp. 553-561 ◽  
Author(s):  
Arnoldo Piccardo ◽  
Matteo Puntoni ◽  
Marih Dezzana ◽  
Gianluca Bottoni ◽  
Luca Foppiani ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Fdg Pet ◽  
Thyroid Nodules ◽  
Thyroid Cytology ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Hounsfield unit value has null effect on thyroid nodules at 18F-FDG PET/CT scans

2018 ◽  
Author(s):  
Filiz Eksi Haydardedeoglu ◽  
Gulay Simsek Bagir ◽  
Nese Torun ◽  
Nazim Emrah Kocer ◽  
Mehmet Reyhan ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Thyroid Nodules ◽  
Hounsfield Unit ◽  
Ct Scans ◽  
Null Effect ◽  
Unit Value ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Hybrid Imaging in Evaluation of Abdominal Sarcoidosis

2018 ◽  
Vol 15 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Isidora Grozdic Milojevic ◽  
Dragana Sobic-Saranovic ◽  
Nebojsa Petrovic ◽  
Slobodanka Beatovic ◽  
Marijana Tadic ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Therapy Response ◽  
Ct Examination ◽  
Abdominal Disease ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
Total Remission ◽  
Active Disease

Objective: To determine the prevalence of abdominal involvement, distribution pattern and evaluate role of hybrid molecular imaging in patients with abdominal sarcoidosis. Methods: Between January 2010 and December 2011, 98 patients with chronic sarcoidosis and presence of prolonged symptoms or other findings suggestive of active disease were referred to FDG PET/CT examination. Active disease was found in 82 patients, and they all were screened for the presence of abdominal sarcoidosis on FDG PET/CT. All patients also underwent MDCT and assessment of serum ACE level. Follow up FDG PET/CT examination was done 12.3±5.4 months after the baseline. Results: Abdominal sarcoidosis was present in 31/82 patients with active sarcoidosis. FDG uptake was present in: retroperitoneal lymph nodes (77%), liver (26%), spleen (23%), adrenal gland (3%). Majority of patients had more than two locations of disease. Usually thoracic disease was spread into the extrathoracic localizations, while isolated abdominal sarcoidosis was present in 10% of patients. After first FDG PET/CT examination therapy was changed in all patients. Eleven patients came to the follow up examination where SUVmax significantly decreased in the majority of them. Three patients had total remission, three had absence of abdominal disease but discrete findings in thorax and others had less spread disease. ACE levels did not correlate with SUVmax level. Conclusion: FDG PET/CT can be a useful tool for detection of abdominal sarcoidosis and in the evaluation of therapy response in these patients. Awareness of the presence of intra-abdominal sarcoidosis is important in order to prevent long-standing unrecognized disease.

Malignes Melanom

2021 ◽  
Vol 12 (01) ◽  
pp. 48-48
Author(s):  
Ine Schmale
Keyword(s):  
Fdg Pet ◽  
Malignes Melanom ◽  
Ct Scans ◽  
Pet Ct ◽  
Fdg Pet Ct

In einer multizentrischen Studie wurde untersucht, ob mithilfe eines FDG-PET-CT-Scans die Entscheidung zum Beenden der Therapie mit Checkpoint-Inhibitoren möglicherweise verbessert werden kann.

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