Identifying A Cut-Off Point for Timed Up and Go Test in Neuromuscular Diseases

Background: The impact of concurrent osteoarthritis on mobility and mortality in individuals with Parkinson’s disease is unknown. Objective: We sought to understand to what extent osteoarthritis severity influenced mobility across time and how osteoarthritis severity could affect mortality in individuals with Parkinson’s disease. Methods: In a retrospective observational longitudinal study, data from the Parkinson’s Foundation Quality Improvement Initiative was analyzed. We included 2,274 persons with Parkinson’s disease. The main outcomes were the effects of osteoarthritis severity on functional mobility and mortality. The Timed Up and Go test measured functional mobility performance. Mortality was measured as the osteoarthritis group effect on survival time in years. Results: More individuals with symptomatic osteoarthritis reported at least monthly falls compared to the other groups (14.5% vs. 7.2% without reported osteoarthritis and 8.4% asymptomatic/minimal osteoarthritis, p = 0.0004). The symptomatic group contained significantly more individuals with low functional mobility (TUG≥12 seconds) at baseline (51.5% vs. 29.0% and 36.1%, p < 0.0001). The odds of having low functional mobility for individuals with symptomatic osteoarthritis was 1.63 times compared to those without reported osteoarthritis (p < 0.0004); and was 1.57 times compared to those with asymptomatic/minimal osteoarthritis (p = 0.0026) after controlling pre-specified covariates. Similar results hold at the time of follow-up while changes in functional mobility were not significant across groups, suggesting that osteoarthritis likely does not accelerate the changes in functional mobility across time. Coexisting symptomatic osteoarthritis and Parkinson’s disease seem to additively increase the risk of mortality (p = 0.007). Conclusion: Our results highlight the impact and potential additive effects of symptomatic osteoarthritis in persons with Parkinson’s disease.

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Muscle ultrasound as a diagnostic tool in neuromuscular diseases

Human Health and Medical Engineering ◽

10.2495/hhme130111 ◽

2014 ◽

Author(s):

Ge Song ◽

Qiu-Ying Jia ◽

Hui Xing ◽

Ying-Qi Xing

Keyword(s):

Diagnostic Tool ◽

Neuromuscular Diseases ◽

Muscle Ultrasound

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Neuromuscular Diseases During Development

Archives of Neurology ◽

10.1001/archneur.55.6.879 ◽

1998 ◽

Vol 55 (6) ◽

pp. 879-879

Author(s):

B. S. Russman

Keyword(s):

Neuromuscular Diseases

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The Six-Minute Walking Test (6WT) and Timed-Up-and-Go (TUG) Test as Measures of Objective Functional Impairment in Patients Undergoing Interlaminar or Transforaminal Epidural Steroid Injection for Lumbar Degenerative Disc Disease (DDD)

Case Medical Research ◽

10.31525/ct1-nct04062942 ◽

2019 ◽

Author(s):

Keyword(s):

Functional Impairment ◽

Steroid Injection ◽

Disc Disease ◽

Timed Up And Go ◽

Lumbar Degenerative Disc Disease ◽

Walking Test ◽

Transforaminal Epidural Steroid Injection ◽

Epidural Steroid ◽

Objective Functional Impairment ◽

Objective Functional

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Eletroestimulação e Crioterapia para espasticidade em pacientes acometidos por Acidente Vascular Cerebral

Revista Neurociências ◽

10.34024/rnc.2011.v19.8415 ◽

2001 ◽

Vol 19 (1) ◽

pp. 77-84 ◽

Cited By ~ 3

Author(s):

Thais Duarte Felice ◽

Raphaela Oliveira Ramos Ishizuka ◽

Jacques Denis Amarilha

Keyword(s):

Timed Up And Go

Vários recursos fisioterapêuticos podem ser instituídos para tratar pacientes no que se refere o controle da espasticidade. Tanto a crioterapia quanto a estimulação elétrica neuromuscular (EENM) apresentam evidências científicas que postulam a redução da espasticidade. Objetivo. Esta pesquisa teve como objetivo avaliar entre as técnicas de EENM e crioterapia, aquela que obtêm a diminuição da espasticidade muscular e a melhora da atividade funcional. Método. Consistiu um estudo de três casos, onde os sujeitos, acometidos por Acidente Vascular Cerebral (AVC) e com quadro de espasticidade no grupo muscular do quadriceps, foram o seu próprio grupo controle. Estes foram submetidos a dois protocolos de tratamento, onde cada terapêutica teve cinco sessões de tratamento em dias consecutivos. Primeiro foi aplicado o Protocolo A (terapêutica com crioterapia), após dois dias, aplicação do Protocolo B (terapêutica com estimulação elétrica neuromuscular). Resultados. Foi observada redução da atividade elétrica muscular, avaliada através da eletromiografia de superfície, e melhora no desempenho funcional, no teste Timed Up and Go, após os tratamentos. Conclusão. A crioterapia e a EENM promoveram redução da atividade elétrica muscular em quadríceps e melhora no desempenho funcional da marcha. Contudo, a crioterapia sobressai a EENM no desempenho muscular.

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