scholarly journals Radical Prostatectomy Outcomes in Patients with Clinical Lymph Node Involvement from The Turkish Urooncology Database

2021 ◽  
Vol 20 (4) ◽  
pp. 231-235
Author(s):  
Hasan Hüseyin Tavukçu ◽  
Oğuzcan Erbatu ◽  
Bülent Akdoğan ◽  
Volkan İzol ◽  
Uğur Yücetaş ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Christopher B. Baker ◽  
Andrew M. McDonald ◽  
Eddy S. Yang ◽  
Rojymon Jacob ◽  
Soroush Rais-Bahrami ◽  
...  

Purpose. To compare oncologic outcomes for patients with Gleason score (GS) ≥ 8 prostate adenocarcinoma treated with radical prostatectomy (RP) versus external beam radiotherapy combined with androgen deprivation (RT + ADT).Methods. Between 2001 and 2014, 121 patients with GS ≥ 8 were treated at our institution via RT + ADT (n=71) or RP (n=50) with ≥ 1 year of biochemical follow-up. Endpoints included biochemical failure (BF), distant metastasis, and initiation of salvage ADT.Results. The RT + ADT group was older, had higher biopsy GS, and had greater risk of lymph node involvement. All other pretreatment characteristics were similar between groups. Mean number of lymph nodes (LNs) sampled for patients undergoing RP was 8.2 (±6.18). Mean biochemical follow-up for all patients was 61 months. Five-year estimates of BF for the RT + ADT and RP groups were 7.2% versus 42.3%, (p<0.001). The RT + ADT group also had lower rates of distant metastasis (2% versus 7.8%) and salvage ADT (8% versus 33.8%).Conclusion. In this analysis, RT + ADT was associated with improved biochemical and metastatic control when compared to RP with limited LN sampling. How RT + ADT compares with more aggressive lymphadenectomy, as is currently our institutional standard, remains an important unanswered question.


2015 ◽  
Vol 193 (4S) ◽  
Author(s):  
Annerleim Walton Diaz ◽  
Steven Abboud ◽  
Arvin George ◽  
Raju Chelluri ◽  
Michele Fascelli ◽  
...  

2012 ◽  
Vol 11 (4) ◽  
pp. 152
Author(s):  
E.P. Popov ◽  
V.V. Sabriev ◽  
A. Vlahova ◽  
T. Dikov ◽  
C.K. Slavov ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 213-213
Author(s):  
Axel Heidenreich ◽  
Carsten H. Ohlmann ◽  
Martin Schuhmacher ◽  
Udo H. Engelmann ◽  
Urs E. Studer

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