AbstractThis article is a continuation of our previous work [7] on the Iwasawa theory of an elliptic modular form over an imaginary quadratic field $K$, where the modular form in question was assumed to be ordinary at a fixed odd prime $p$. We formulate integral Iwasawa main conjectures at non-ordinary primes $p$ for suitable twists of the base change of a newform $f$ to an imaginary quadratic field $K$ where $p$ splits, over the cyclotomic ${\mathbb{Z}}_p$-extension, the anticyclotomic ${\mathbb{Z}}_p$-extensions (in both the definite and the indefinite cases) as well as the ${\mathbb{Z}}_p^2$-extension of $K$. In order to do so, we define Kobayashi–Sprung-style signed Coleman maps, which we use to introduce doubly signed Selmer groups. In the same spirit, we construct signed (integral) Beilinson–Flach elements (out of the collection of unbounded Beilinson–Flach elements of Loeffler–Zerbes), which we use to define doubly signed $p$-adic $L$-functions. The main conjecture then relates these two sets of objects. Furthermore, we show that the integral Beilinson–Flach elements form a locally restricted Euler system, which in turn allow us to deduce (under certain technical assumptions) one inclusion in each one of the four main conjectures we formulate here (which may be turned into equalities in favorable circumstances).