The Negro Family | ScienceGate

SummaryThree cases of hereditary myoclonic epilepsy have been observed among ten siblings in a Negro family. Electroencephalograms of the parents, three normal siblings and two of the three affected siblings have been recorded and all show abnormalities of a similar type. These are of a generalized nature revealing no focal damage. This type of abnormality has been observed in an affected male and two normal siblings by Watson and Denny-Brown.The autosomal recessive mode of inheritance observed in the present study is consistent with the transmission most frequently reported in myoclonic epilepsy. We believe that abnormal electroencephalographic patterns are associated with this gene and that these patterns may be useful in the detection of heterozygous carriers.

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Negro Family Types in a Cuban Solar

Phylon (1940-1956) ◽

10.2307/271148 ◽

1950 ◽

Vol 11 (2) ◽

pp. 159

Author(s):

David W. Ames

Keyword(s):

Negro Family ◽

Family Types

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A Family with Hemoglobin I

Blood ◽

10.1182/blood.v22.3.313.313 ◽

1963 ◽

Vol 22 (3) ◽

pp. 313-322 ◽

Cited By ~ 5

Author(s):

OSCAR L. THOMPSON ◽

HARRIS J. MORELAND ◽

GERALD W. SMITH ◽

BARBARA H. BOWMAN ◽

MARTHA JEANNIE ALEXANDER ◽

...

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Gel Electrophoresis ◽

Minor Component ◽

Agar Gel ◽

Negro Family ◽

Α Chain ◽

Agar Gel Electrophoresis

Abstract Hemoglobin I was recently found in a Negro family. The amino acid substitution was shown to occur in the sixteenth residue of the α chain (lys → asp) and to be identical with hemoglobin I described by Murayama.10 The minor component, I2, was demonstrated by agar gel electrophoresis.

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