scholarly journals A Case Report Discussing an Uncommon Peripheral Exudative Hemorrhagic Chorioretinopathy

2021 ◽  
Author(s):  
Marlon Demeritt ◽  
Beata Lewandowska
Keyword(s):  
Case Report ◽  
Subretinal Fluid ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
White Female ◽  
Care Providers ◽  
Pigment Epithelial ◽  
Age Related ◽  
Visual Complaints ◽  
Intraretinal Hemorrhages

Purpose: The purpose of this case report is to discuss an uncommon, unique hemorrhagic chorioretinopathy. Method: A 79-year-old-white female presented to clinic with complaints of difficulty reading at close distances and seeing faces at far distances in both eyes. An 85-year old white female presented with no visual complaints but stated redness in the nasal corner of her right eye. This is a case report of two patients that presented with geographic atrophy of the macula as well as midperipheral RPE alterations in both eyes, which resembled intraretinal hemorrhages. Results: The ocular findings associated with peripheral exudative hemorrhagic chorioretinopathy may include midperipheral intraretinal hemorrhages, peripheral RPE mottling, subretinal fluid or hemorrhages, subretinal exudation, pigment epithelial detachments, and/or vitreous hemorrhages. Conclusions: Although this condition is rare, primary eye care providers should be aware of this unique clinical entity, its relationship to age-related macular degeneration, and when these patients require a referral to a retinal specialist.

scholarly journals Morphologic Changes in Patient with Drusen and Drusenoid Pigment Epithelial Detachment after Intravitreal Ranibizumab for Choroidal Neovascular Membrane : A Case Report

2016 ◽  
Vol 10 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Sukjin Kim ◽  
Jeongjae Oh ◽  
Kiseok Kim
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Age Related Macular Degeneration ◽  
Pigment Epithelial Detachment ◽  
Choroidal Neovascular Membrane ◽  
Intravitreal Ranibizumab ◽  
Pigment Epithelial ◽  
Age Related ◽  
The Right ◽  
Morphologic Changes

The authors present a case of morphologic changes of drusen and drusenoid pigment epithelial detachment (DPED) after treating choroidal neovascularization (CNV) using ranibizumab in age-related macular degeneration (AMD). A 71-year-old woman has noticed mild visual acuity deterioration in the right eye for several months. She was presented with some drusen and DPED associated with CNV. This patient was given intravitreal injection of 0.5 mg of ranibizumab five times at monthly intervals for treating CNV. DPED in the temporal and drusen in the superior to macula were diminished, which continued up to 2 months. Intravitreal ranibizumab injection may have influenced with diminishment of drusen and DPED. After 2 months, CNV was recurred.

scholarly journals Prognostic value of intermediate age-related macular degeneration phenotypes for geographic atrophy progression

2020 ◽  
pp. bjophthalmol-2020-316004 ◽  
Author(s):  
Sarah Thiele ◽  
Jennifer Nadal ◽  
Maximilian Pfau ◽  
Marlene Saßmannshausen ◽  
Monika Fleckenstein ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Prognostic Value ◽  
Retinal Pigment ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Progression Rate ◽  
Precursor Lesions ◽  
Pigment Epithelial ◽  
Age Related ◽  
The Impact

BackgroundTo characterise early stages of geographic atrophy (GA) development in age-related macular degeneration (AMD) and to determine the prognostic value of structural precursor lesions in eyes with intermediate (i) AMD on the subsequent GA progression.MethodsStructural precursor lesions for atrophic areas (lesion size at least 0.5 mm² in fundus autofluorescence images) were retrospectively identified based on multimodal imaging and evaluated for association with the subsequent GA enlargement rates (square-root transformed, sqrt). A linear mixed-effects model was used to account for the hierarchical nature of the data with a Tukey post hoc test to assess the impact of the local precursor on the subsequent GA progression rate.ResultsA total of 39 eyes with GA of 34 patients with a mean age of 74.4±6.7 (±SD) years were included in this study. Five precursor lesions (phenotypes 1–5) preceding GA development were identified: large, sub-retinal pigment epithelial drusen (n=19), reticular pseudodrusen (RPD, n=10), refractile deposits (n=4), pigment epithelial detachment (n=4) and vitelliform lesions (n=2). Precursor lesions exhibited a significant association with the subsequent (sqrt) GA progression rates (p=0.0018) with RPD (phenotype 2) being associated with the fastest GA enlargement (2.29±0.52 (±SE) mm/year.ConclusionsThe results indicate the prognostic relevance of iAMD phenotyping for subsequent GA progression highlighting the role of structural AMD features across different AMD stages.

Non-neovascular age-related macular degeneration with subretinal fluid

2020 ◽  
pp. bjophthalmol-2020-317326 ◽  
Author(s):  
Assaf Hilely ◽  
Adrian Au ◽  
K Bailey Freund ◽  
Anat Loewenstein ◽  
Eric H Souied ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Retinal Pigment Epithelial ◽  
Retinal Pigment ◽  
Subretinal Fluid ◽  
Age Related Macular Degeneration ◽  
Neovascular Amd ◽  
Pigment Epithelial ◽  
Age Related ◽  
Sd Oct

PurposeTo evaluate the various patterns of subretinal fluid (SRF) in eyes with age-related macular degeneration (AMD) in the absence of macular neovascularisation (MNV) and to assess the long-term outcomes in these eyes.MethodsThis retrospective study included only eyes with non-neovascular AMD and associated SRF. Eyes with evidence of MNV were excluded. Spectral-domain optical coherence tomography (SD-OCT) was obtained at baseline and at follow-up, and qualitative and quantitative SD-OCT analysis of macular drusen including drusenoid pigment epithelial detachment (PED) and associated SRF was performed to determine anatomic outcomes.ResultsForty-five eyes (45 patients) were included in this analysis. Mean duration of follow-up was 49.7±36.7 months. SRF exhibited three different morphologies: crest of fluid over the apex of the drusenoid PED, pocket of fluid at the angle of a large druse or in the crypt of confluent drusen or drape of low-lying fluid over confluent drusen. Twenty-seven (60%) of the 45 eyes with fluid displayed collapse of the associated druse or drusenoid PED and 24 (53%) of the 45 eyes developed evidence of complete or incomplete retinal pigment epithelial and outer retinal atrophy.ConclusionNon-neovascular AMD with SRF is an important clinical entity to recognise to avoid unnecessary anti-vascular endothelial growth factor therapy. Clinicians should be aware that SRF can be associated with drusen or drusenoid PED in the absence of MNV and may be the result of retinal pigment epithelial (RPE) decompensation and RPE pump failure.

scholarly journals Systemic steroids for the management of choroidal neovascular membrane with pigment epithelial tear and recalcitrant subretinal fluid

2019 ◽  
Vol 12 (9) ◽  
pp. e231262
Author(s):  
Alper Bilgic ◽  
Aditya Sudhalkar
Keyword(s):  
Retinal Pigment ◽  
Disease Process ◽  
Subretinal Fluid ◽  
Age Related Macular Degeneration ◽  
Final Visit ◽  
Systemic Steroids ◽  
Pigment Epithelial ◽  
Age Related ◽  
The Right ◽  
Rpe Tear

A 67-year-old man was diagnosed to have dry age related macular degeneration in the right eye and a choroidalneovascular membrane (CNVM) with a large pigment epithelial detachment in the left eye, confirmed with clinical examination, angiography and optical coherence tomography scans. He received an intravitreal injection of bevacizumab in the right eye and developed a retinal pigment epithelial (RPE) tear 3 weeks later. 3 consecutive ranibizumab injections failed to clear the subretinal fluid (SRF). A course of systemic steroids was administered and this improved the vision. Subsequently, the patient received one more ranibizumab injection and the disease process resolved. The left eye corrected distance visual acuity (LE CDVA) was 20/30 at the final visit (1 year after the last injection). Systemic steroids may be a management option in patients with CNVM and RPE tear with recalcitrant SRF if there is no contraindication to their use.

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