An unusual presentation of Ewing sarcoma mimicking Guillain–Barré syndrome in a 17-year-old male

Author(s):  
Ozgur Deniz Sadioglu ◽  
Ozgur Sogut ◽  
Baris Agca

Abstract The management of a patient admitted to the emergency department with symptoms of Guillain–Barré syndrome (GBS), including paraplegia, who was subsequently diagnosed with Ewing sarcoma (ES) and spinal cord compression using MRI is discussed here. Pathological report confirmed the diagnosis of ES. The patient underwent immediate neurosurgery due to rapid progression of paraplegia. Keywords: Ewing sarcoma, Paraplegia, Guillain–Barré syndrome, Spinal cord compression

1994 ◽  
Vol 25 (01) ◽  
pp. 36-38 ◽  
Author(s):  
K. Gücüyener ◽  
S. Keskil ◽  
M. Baykaner ◽  
E. Bilir ◽  
A. Oğuz ◽  
...  

Radiographics ◽  
2019 ◽  
Vol 39 (6) ◽  
pp. 1862-1880 ◽  
Author(s):  
Olga Laur ◽  
Hari Nandu ◽  
David S. Titelbaum ◽  
Diego B. Nunez ◽  
Bharti Khurana

2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.


2019 ◽  
Vol 48 (4) ◽  
pp. 030006051989316
Author(s):  
Kuang-Heng Lee ◽  
Tsung-Han Ho ◽  
Jiunn-Tay Lee ◽  
Li-Fan Lin ◽  
Wei-Chou Chang ◽  
...  

Guillain–Barré syndrome (GBS) is an acute neuroimmunological disorder characterized by rapidly ascending symmetrical limb weakness, areflexia, and sensory deficits. Approximately 65% of patients with GBS present with autonomic dysfunction, which commonly occurs in advanced stages. However, paralytic ileus, a sign of gastrointestinal dysautonomia, is rare as the presenting feature in GBS before motor weakness becomes evident. We report the case of a 54-year-old man admitted to the Emergency Department with paralytic ileus as the prodromal feature in early-stage GBS. Total parenteral feeding and prokinetic use were initiated, but no clinical improvement was observed. The patient showed rapid progression to quadriplegia, which was ultimately determined to be respiratory muscle failure requiring mechanical ventilation and intensive care unit admission. He underwent 5 days of intravenous immunoglobulin therapy and muscle strength was partially improved thereafter. However, the patient’s enteral nutritional support was undesirable because of persistent poor gastric emptying complicated by fungemia and profound sepsis throughout the hospital course. Finally, he died 1 month after admission. Ignorance of this unusual prodrome to GBS could result in delayed treatment, along with potential progression to life-threatening events. Early recognition of GBS and prompt immunotherapy are critical for reducing morbidity and mortality.


Author(s):  
Mohammad Darvishi ◽  
Hamze Shahali ◽  
Azade Amirabadi Farahani

A 56-year-old man was referred to the emergency department for the subacute onset of and weakness in the lower extremities, paraesthesia and pain. He was diagnosed with SARS-CoV-2 pneumonia and then, he received the necessary treatment according to national protocol. Radiographic, laboratory, and electroneurographic findings indicated an acute polyradiculoneuritis with prominent demyelination and suggesting the diagnosis of Guillain-Barr syndrome associated with COVID-19 infection.


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