scholarly journals Rare variant of Guillain-Barré syndrome after chikungunya viral fever

2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.

2021 ◽  
Vol 429 ◽  
pp. 119936
Author(s):  
Valentina Tommasini ◽  
Mauro Catalan ◽  
Lucia Antonutti ◽  
Giulia Mazzon ◽  
Marta Cheli ◽  
...  

2017 ◽  
Vol 5 (2) ◽  
pp. 129-131
Author(s):  
Uzzwal Kumar Mallick ◽  
Badrul Alam ◽  
Mohammad Asaduzzaman

Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy. In typical cases, the first symptoms of GBS are pain, numbness, paresthesia, weakness in the limbs. Autonomic involvement is common and causes urinary retention and ileus. Most of these symptoms overlap with those of cervical myelopathy. Therefore, correct diagnosis of GBS in a patient with symptomatic cervical myelopathy or in a patient with atypical manifestations of GBS can be difficult, especially early in the course of GBS. We report a 60-year-old man who was admitted to the neurosurgery department with worsening neck pain, numbness and weakness in the hands initially thought to be secondary to progressive cervical myelopathy. However, his symptoms rapidly progressed to flaccid areflexic quadriparesis and respiratory difficulty within few days and shifted to ICU for ventilator support. Electrophysiological studies and cerebrospinal fluid analysis were consistent with an acquired demyelinating polyradiculoneuropathy. We planned for immunotherapy with intravenous immunoglobulin , but his condition was improving day by day with conservative treatment , so immunotherapy with intravenous immunoglobulin was not initiated. Any patient presenting as unexplain Cervical myelopathy, GBS should be kept in mind before planning any surgical intervention.Bangladesh Crit Care J September 2017; 5(2): 129-131


2012 ◽  
Vol 03 (01) ◽  
pp. 36-39 ◽  
Author(s):  
Harmanjit Singh Hira ◽  
Amandeep Kaur ◽  
Anuj Shukla

ABSTRACT Background: Dengue infections may present with neurological complications. Whether these are due to neuromuscular disease or electrolyte imbalance is unclear. Materials and Methods: Eighty-eight patients of dengue fever required hospitalization during epidemic in year 2010. Twelve of them presented with acute neuromuscular weakness. We enrolled them for study. Diagnosis of dengue infection based on clinical profile of patients, positive serum IgM ELISA, NS1 antigen, and sero-typing. Complete hemogram, kidney and liver functions, serum electrolytes, and creatine phosphokinase (CPK) were tested. In addition, two patients underwent nerve conduction velocity (NCV) test and electromyography. Results: Twelve patients were included in the present study. Their age was between 18 and 34 years. Fever, myalgia, and motor weakness of limbs were most common presenting symptoms. Motor weakness developed on 2 nd to 4 th day of illness in 11 of 12 patients. In one patient, it developed on 10 th day of illness. Ten of 12 showed hypokalemia. One was of Guillain-Barré syndrome and other suffered from myositis; they underwent NCV and electromyography. Serum CPK and SGOT raised in 8 out of 12 patients. CPK of patient of myositis was 5098 IU. All of 12 patients had thrombocytopenia. WBC was in normal range. Dengue virus was isolated in three patients, and it was of serotype 1. CSF was normal in all. Within 24 hours, those with hypokalemia recovered by potassium correction. Conclusions: It was concluded that the dengue virus infection led to acute neuromuscular weakness because of hypokalemia, myositis, and Guillain-Barré syndrome. It was suggested to look for presence of hypokalemia in such patients.


Author(s):  
Mohammad Darvishi ◽  
Hamze Shahali ◽  
Azade Amirabadi Farahani

A 56-year-old man was referred to the emergency department for the subacute onset of and weakness in the lower extremities, paraesthesia and pain. He was diagnosed with SARS-CoV-2 pneumonia and then, he received the necessary treatment according to national protocol. Radiographic, laboratory, and electroneurographic findings indicated an acute polyradiculoneuritis with prominent demyelination and suggesting the diagnosis of Guillain-Barr syndrome associated with COVID-19 infection.


2019 ◽  
Vol 10 (10.2) ◽  
pp. 98-102 ◽  
Author(s):  
Mihai Sava ◽  
Maria-Gabriela Catană ◽  
Corina Roman-Filip

Abstract Guillain-Barre syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide, having an incidence of about 1/100,000 across several studies in a number of countries. We present the case of a 60-year-old female patient, with known hypertension, admitted to our department for paresthesia and muscle weakness predominantly in the distal upper and lower limbs. Symptomatology had an acute onset after 14 days from influenza vaccine administration. Lumbar puncture revealed CSF glucose (91 mg/dl), CSF protein (0.508 g/l) and no pleocytosis. Electromyography supported the presumptive diagnosis of polyradiculoneuritis. The patient underwent three sessions of double filtration and the final diagnosis was Guillain-Barre polyradiculoneuritis secondary to influenza vaccination. Approximately 80% of patients with polyradiculoneuritis recover completely within a few months to one year; however, 5-10% of these patients experience one or more recurrences. It should be emphasized that acute-phase rehabilitation must start immediately and include an individualized program of gentle strengthening, and manual resistive and progressive resistive exercises. Key words: polyradiculoneuropathy, influenza vaccine, neurorehabilitation,


Cureus ◽  
2021 ◽  
Author(s):  
Sadia Waheed ◽  
Angel Bayas ◽  
Fawzi Hindi ◽  
Zufe Rizvi ◽  
Patricio S Espinosa

2019 ◽  
Vol 12 (11) ◽  
pp. e230650 ◽  
Author(s):  
Rahul Jain ◽  
Pankaj Satyanarayan Rathi ◽  
Kapil Telang ◽  
Alia Zaidi

Guillain-Barre syndrome (GBS) in pregnancy is a rare co-occurrence and it is generally accepted that it carries a high maternal risk. We report a 40-year-old housewife who developed GBS with respiratory failure during the third trimester (31 weeks of gestation). She had preterm vaginal delivery on ventilator support at 34 weeks of gestation in neurology intensive care unit. She managed successfully with ventilatory support, intravenous immunoglobulin and other supportive measures.


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