scholarly journals Association of Age With Lower Urinary Tract Function in Adult Men Presenting for Urodynamics: A Database Analysis

Author(s):  
Sanjay Sinha ◽  
Lavina Matina

Background: Knowledge regarding lower urinary tract function in adult men could help in making informed choices. Few studies have examined the entire spectrum of adult males. Methods: This is a retrospective analysis of all adult men with refractory non-neurogenic urinary symptoms presenting to a tertiary center over 9 years. International Continence Society defined indices bladder outlet obstruction index (BOOI) and bladder contractility index (BCI) were calculated with established classification. Storage abnormality was defined as presence of detrusor overactivity, poor compliance (< 20mL per cm H20) or both. Data were analyzed by non-parametric tests using SPSS (version 20.0.0, Armonk NY ) (P < 0.05 significant; 2-tailed). Where appropriate, correction for multiple hypothesis testing was applied. Results: A total of 1596 men (range 18 to 91 years, median 51.0 years; IQR 34 to 64 years) were eligible. Median BCI and BOOI were 99.5 and 37.0, respectively, and a storage abnormality was noted in 41.7%. On multivariate analysis, age was significantly associated with urodynamic findings. While not strictly linear, for each 10 years increase in age, on average, the BCI fell 2.4 points and the BOOI increased by 2.4 points. Increasing age was also associated with increasing odds of finding a storage abnormality (OR 1.015; 95%CI 1.008 to 1.022; P < 0.001). On post hoc analysis (Bonferroni correction), men under 30 years were least likely of any group to show obstruction (30.3%; median BOOI 26). Conclusions: Adult men with refractory urinary symptoms show age-associated differences in urodynamic findings. An awareness of these trends can help take more informed decisions in clinical care.

2018 ◽  
Vol 80 (3-4) ◽  
pp. 121-125
Author(s):  
Ryuji Sakakibara ◽  
Ayami Shimizu ◽  
Osamu Takahashi ◽  
Fuyuki Tateno ◽  
Masahiko Kishi ◽  
...  

In order to investigate lower urinary tract function in hereditary spastic paraplegia (HSP), we recruited 12 HSP patients: 8 men, 4 women; mean age, 64.6 years; mean disease duration, 18.9 years; walk without cane, 2, walk with cane, 6, wheelchair bound, 3. We performed urinary symptom questionnaires and a urodynamic testing in all patients. As a result, urinary symptoms were observed in all but 3, including urinary urgency/frequency (also called overactive bladder) in 9 and hesitancy/poor stream in 6. Urodynamic abnormalities included detrusor overactivity during bladder filling in 10, underactive detrusor on voiding in 8 (detrusor hyperactivity with impaired contraction [DHIC] in 5), detrusor-sphincter dyssynergia (DSD) on voiding in 3, and post-void residual in 5. Sphincter electromyography showed neurogenic motor unit potential in 4. In conclusion, we observed high frequency of urinary symptoms in HSP. Urodynamics indicated that the main mechanism is DHIC with/without DSD for their urinary symptom, and sacral cord involvement in some cases. These findings facilitate patients’ care including clean, intermittent catheterization.


Choonpa Igaku ◽  
2014 ◽  
Vol 41 (6) ◽  
pp. 819-825
Author(s):  
Naoki WADA ◽  
Hidehiro KAKIZAKI

Author(s):  
Nobuhiro Haga ◽  
Yu Okabe ◽  
Takeshi Miyazaki ◽  
Kazuna Tsubouchi ◽  
Hidenori Akaihata ◽  
...  

1988 ◽  
Vol 7 (5) ◽  
pp. 403-427 ◽  
Author(s):  
Paul Abrams ◽  
Jerry G. Blaivas ◽  
Stuart L. Stanton ◽  
Jens T. Andersen

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