Tetracyclines, Chloramphenicol and Aminoglycoside Antibiotics

Author(s):  
KD Tripathi
2020 ◽  
Vol 65 (7-8) ◽  
pp. 37-41
Author(s):  
E. N. Semenova ◽  
S. I. Kuleshova ◽  
E. I. Sakanyan

A method for the quantitative determination of streptomycin sulfate in medicines by the turbidimetric method has been developedand validated. Based on the results of the experiments, it was found that the metrological characteristics of such validation parameters of the method as linearity, precision, and correctness do not exceed the validation criteria. Linearity was noted in the range of streptomycin concentrations from 3.75 to 8.43 μg/ml. The results of validation tests of the method for the quantitative determination of streptomycin indicate the prospects and feasibility of introducing the turbidimetric method into the domestic system for standardization and quality assessment of aminoglycoside antibiotics.


1985 ◽  
Vol 68 (5) ◽  
pp. 1007-1013
Author(s):  
Badar Shaikh ◽  
Edward H Allen

Abstract A survey of literature is presented dealing with physical-chemical methods for the detection and quantitation of aminoglycoside antibiotics (gentamicin, streptomycin, dihydrostreptomycin, and neomycin) that are used in food-producing animals. Recent developments in cleanup and determinative procedures, particularly liquid chromatography, for these compounds in fluids and tissues are emphasized. Little research has been done on residues in tissues compared with other biological matrices. This review also covers the chemistry, general characteristics, tolerances, and withdrawal times for the approved uses of these antibiotics in animals that are used for food.


1984 ◽  
Vol 122 (1) ◽  
pp. 460-465 ◽  
Author(s):  
Nobuo Tanaka ◽  
Keita Matsunaga ◽  
Hiroshi Yamaki ◽  
Toshio Nishimura

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