scholarly journals Skin perfusion pressure for the prediction of wound healing in critical limb ischemia: a meta-analysis

2018 ◽  
Vol 14 (3) ◽  
pp. 481-487 ◽  
Author(s):  
Xuanliang Pan ◽  
Chuangang You ◽  
Guoxian Chen ◽  
Huawei Shao ◽  
Chunmao Han ◽  
...  
1997 ◽  
Vol 26 (4) ◽  
pp. 629-637 ◽  
Author(s):  
John J. Castronuovo ◽  
Habtu M. Adera ◽  
Janice M. Smiell ◽  
Ray M. Price

Angiology ◽  
2015 ◽  
Vol 66 (9) ◽  
pp. 862-866 ◽  
Author(s):  
Shin Okamoto ◽  
Osamu Iida ◽  
Masato Nakamura ◽  
Yasutaka Yamauchi ◽  
Masashi Fukunaga ◽  
...  

2013 ◽  
Vol 46 (03) ◽  
pp. 508-512 ◽  
Author(s):  
Tota Kawasaki ◽  
Tetsuji Uemura ◽  
Kiyomi Matsuo ◽  
Kazuyuki Masumoto ◽  
Yoshimi Harada ◽  
...  

ABSTRACTWe have encountered situations of patients with critical limb ischemia accompanied by pain at rest and necrosis, who hang their legs down from the bed during sleep. This lower limb position is known to be a natural position, which reduces pain in the lower extremity induced by ischemia. However, the effect of this position on blood flow of the lower extremity is poorly understood. We studied whether measurements of skin perfusion pressure (SPP) changes by leg position and the difference between healthy adults and patients with critical limb ischemia. The subjects of this study were 10 healthy adults and 11 patients with critical limb ischemia. Patients with critical limb ischemia, including both dorsum of foot and plantar of foot, having SPP of lower limbs of less than 40 mmHg (supine position) were the object of this study. SPP was measured on four positions (supine position, lower limbs elevation position, sitting position, and reclining bed elevation of 20° position). In sitting position, both the number of healthy adults and critical patients show significant increases in SPP compared with the other three positions. These results suggest that sitting position is effective to keep good blood stream of lower limbs not only in healthy adults but also in patients with critical limb ischemia. However, an appropriate leg position should not have lower limbs hang downwards for long periods time because edema is caused by the fall in venous return in lower limbs, and the wound healing is prolonged.Our clinical research could be more useful in the future, particularly in developing countries, for surgeons managing wounds in leg and foot and preserving ischemic limbs.


2019 ◽  
Vol 19 (1) ◽  
pp. 57-62
Author(s):  
Hideharu Nakamura ◽  
Takaya Makiguchi ◽  
Daisuke Atomura ◽  
Yukie Yamatsu ◽  
Ken Shirabe ◽  
...  

Hyperbaric oxygen (HBO) therapy promotes wound healing in patients with ischemic disease; however, HBO-induced changes in skin peripheral circulation have not been evaluated in clinical practice. Here, we investigated these changes in patients with critical limb ischemia (CLI), with a focus on the angiosome of crural blood vessels with blood flow improved by endovascular therapy (EVT). Six patients with CLI and ulcers who were treated with HBO after EVT (7 limbs; 1 patient had ulcers in the bilateral limbs) and 3 healthy subjects (6 limbs) were enrolled. HBO therapy was performed at 2 atm under 100% oxygen for 90 min per session. Skin perfusion pressure (SPP) was measured in the dorsum and sole of the foot 1 hour before (pre-SPP) and after (post-SPP) HBO therapy. ΔSPP was calculated as post-SPP minus pre-SPP. SPP measurement regions were divided into those that did (direct region) and did not (indirect region) correspond to the vascular angiosome in which angiography findings of the crus were improved after EVT; i.e., when the anterior tibial artery was effectively treated with EVT, the dorsum was the direct region and the sole was the indirect region, and vice versa when the posterior tibial artery was treated. In the direct, indirect, and healthy subject groups, the ΔSPPs were 20.5±8.7 (p=0.002), –6.4±10.9, and –15.1±18.1 (p=0.014), respectively; that of the direct group was significantly greater than that of the other groups. These results suggest that short-term improvement of the peripheral circulation by HBO therapy was significant in patients with successful revascularization.


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