scholarly journals Prevention and management of urinary stone

2020 ◽  
Vol 63 (11) ◽  
pp. 684-695
Author(s):  
Hae Do Jung ◽  
Joo Yong Lee

The prevalence of urolithiasis is increasing not only in South Korea but also around the world. Urolithiasis has a high recurrence rate, therefore, reducing it is very important in the quality of life for stone formers. For this purpose, dietary modifications and drug therapy can be performed through stone analysis and 24-hour urine collection. Stone analysis is recommended for all stone formers, and the 24-hour urine collection is usually recommended for recurrent stone formers or high-risk groups. A general dietary modification for all stone formers includes a sufficient fluid intake, low levels of sodium, sugar, and animal protein, a normal calcium diet, as well as a high amount of citrate intake. Drug therapy should be performed in cases such as the recurrence of stones or increase of the existing ones, even after the application of preservation therapy, such as dietary modification. The ideal drug therapy should prevent the occurrence of urolithiasis, have no side effects, and have a suitable patientsʼ compliance. Follow-up should be performed periodically, through 24-hour urine collections and imaging studies. For follow-up imaging studies, a lowdose non-enhanced computed tomography is recommended, and it can be performed once a year if the patient is in a stable state. To control various and complex metabolic abnormalities in recurrent stone formers, multiple approaches may be required through diet modifications, drug therapy, treatment of the metabolic syndrome, and lifestyle modifications.

2010 ◽  
Vol 105 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Noor Buchholz ◽  
Tamer El-Husseiny ◽  
Konstantinos Moraitis ◽  
Zafar Maan ◽  
Junaid Masood

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Eric R. Neumaier ◽  
Lori L. DuBenske ◽  
William T. Hoyt ◽  
Stephen Y. Nakada ◽  
Kristina L. Penniston

1987 ◽  
Vol 33 (7) ◽  
pp. 1118-1120 ◽  
Author(s):  
B C McWhinney ◽  
S L Nagel ◽  
D M Cowley ◽  
J M Brown ◽  
A H Chalmers

Abstract We used a xylitol load to test the two-carbon pathway to oxalate production in humans. Use of this pentose sugar caused a fourfold increase in glycolate excretion, indicating its suitability as a dynamic function test of two-carbon metabolism. However, despite this increase in glycolate excretion in 10 recurrent stone formers and six normal subjects, there was no concomitant increase in oxalate excretion in either group. By comparison, a sucrose load produced no increase in excretion of either glycolate or oxalate. In addition, when we studied four recurrent calcium stone formers on successive diets with various fat content, we found no correlation between high fat intake and increased glycolate or oxalate excretion. In summary, there was no evidence of abnormal fluxes through the two-carbon pathway to oxalate in recurrent stone formers, nor of hyperoxaluria as related to increased intake of sucrose or fat.


1986 ◽  
Vol 32 (2) ◽  
pp. 333-336 ◽  
Author(s):  
A H Chalmers ◽  
D M Cowley ◽  
J M Brown

Abstract Studies of recurrent stone formers indicated that they have significantly increased urinary oxalate and decreased ascorbate excretions. Results of oral and intravenous administration of ascorbate indicate an enhanced production of oxalate from ascorbate in recurrent calcium stone formers as compared with normal persons and that most of this oxalate is generated in the gut.


2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
John Knoedler ◽  
Mitra de Cogain ◽  
John Lieske ◽  
Terri Vrtiska ◽  
Xijuan Li ◽  
...  

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Terence Lee ◽  
Mohamed Elkoushy ◽  
Sero Andonian

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