Smooth muscle tumour of uncertain malignant potential (STUMP) diagnosed by hysteroscopic surgery : Report of a case

2010 ◽  
Vol 26 (2) ◽  
pp. 405-409
Author(s):  
Yusuke Matsuura ◽  
Chiho Hatae ◽  
Toshinori Kawagoe ◽  
Naoyuki Toki ◽  
Toru Hachisuga ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Hysteroscopic Surgery

Unusual morphological features of uterine leiomyomas treated with progestogens

2011 ◽  
Vol 64 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Clinton Boyd ◽  
W Glenn McCluggage
Keyword(s):  
Smooth Muscle ◽  
Mitotic Activity ◽  
Intrauterine Device ◽  
Malignant Potential ◽  
Morphological Features ◽  
Uterine Leiomyomas ◽  
Pathological Features ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Benign Leiomyoma

BackgroundUterine leiomyomas are extremely common in surgical pathology practice and in the vast majority there are no issues in diagnosis. Progestogens are widely prescribed drugs for a variety of indications, including abnormal uterine bleeding, and are often given to women with leiomyomas but the pathological features of leiomyomas treated with progestogens are poorly described.MethodsWe report the pathological features in eight cases of uterine leiomyomas in women who had been treated with oral progestogens or a progestogen-containing intrauterine device; all cases were received in consultation because the features raised concern for leiomyosarcoma, smooth muscle tumour of uncertain malignant potential or a benign leiomyoma with unusual features. Additionally, we reviewed a series of cases of uterine leiomyomas (n=99) in women who exhibited progestogenic effects in the endometrium.ResultsThe morphological features in the consult cases, which were widespread and marked and which varied somewhat from case to case, included small and/or large areas of infarct-type necrosis (sometimes mimicking coagulative tumour cell necrosis) with surrounding increased cellularity, mitotic activity, nuclear pyknosis, cytoplasmic eosinophilia, epithelioid morphology, stromal oedema, haemorrhage, and myxoid change and infiltration by CD56 positive granulated lymphocytes. Sometimes the features resulted in an almost deciduoid appearance. Similar features were present to a minor degree in significant numbers of the additional series of cases.ConclusionsPathologists should be aware of these progestogen-associated features when reporting uterine leiomyomas whether or not the clinician has indicated that the woman is taking progestogens since otherwise a diagnosis of leiomyosarcoma or smooth muscle tumour of uncertain malignant potential may be rendered. Useful features in suggesting a benign leiomyoma, in addition to recognition of the morphological features described which, in combination, are characteristic of progestogens, are the lack of true nuclear atypia and the low mitotic activity away from the abnormal areas.

scholarly journals A large and late mediastinal metastasis from a uterine smooth muscle tumour of uncertain malignant potential: A case report

2021 ◽  
pp. 106734
Author(s):  
Angelo Paolo Ciarrocchi ◽  
Beatrice Aramini ◽  
Stefano Sanna ◽  
Giulio Rossi ◽  
Desideria Argnani ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Uterine Smooth Muscle ◽  
Mediastinal Metastasis

scholarly journals Smooth muscle tumour of uncertain malignant potential (SMTUMP) in the nasal cavity: an incidental finding

2016 ◽  
pp. bcr2016217386 ◽  
Author(s):  
Dipak Ranjan Nayak ◽  
Asheesh Dora Ghanpur ◽  
Apoorva N Reddy ◽  
Swati Sharma
Keyword(s):  
Smooth Muscle ◽  
Nasal Cavity ◽  
Incidental Finding ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour

scholarly journals Hormone dependency in metastatic low-grade leiomyosarcoma following uterine smooth muscle tumour of uncertain malignant potential

2014 ◽  
Vol 2014 (mar27 1) ◽  
pp. bcr2013202107-bcr2013202107 ◽  
Author(s):  
C. Serrano ◽  
M. R. Nucci ◽  
S. H. Tirumani ◽  
C. P. Raut ◽  
S. George
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Low Grade ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Uterine Smooth Muscle ◽  
Hormone Dependency

scholarly journals Airway recanalization of bronchial metastasis and obstruction by smooth muscle tumour of uncertain malignant potential by a silicone OKI‐stent ™

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Atsushi Torii ◽  
Hideo Saka ◽  
Rieko Nishimura ◽  
Yushi Saito ◽  
Masahide Oki
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour

Stanford parameters stratify the risk of recurrence in gynecologic smooth muscle tumors of uncertain malignant potential (STUMP)

Apmis ◽  
2021 ◽  
Author(s):  
Antonio Travaglino ◽  
Antonio Raffone ◽  
Annarita Gencarelli ◽  
Carola Caldarelli ◽  
Marcello Granata ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Risk Of Recurrence ◽  
Smooth Muscle Tumors

Uterine smooth muscle tumors of uncertain malignant potential: a case presentation

2011 ◽  
Vol 16 (5) ◽  
pp. 592-595 ◽  
Author(s):  
Kazım Gezginç ◽  
Fatma Yazici ◽  
Lema Tavli
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Case Presentation ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors
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