scholarly journals Toxicity of ethylene glycol monomethyl ether on reproduction parameters and histomorphological changes in Wistar rats

2021 ◽  
Vol 52 (1) ◽  
pp. 65-72
Author(s):  
Satish T. Panchal ◽  
Kauresh D. Vachhrajani ◽  
Parimal Solanki ◽  
Piyush Pate
1993 ◽  
Vol 9 (4) ◽  
pp. 617-622 ◽  
Author(s):  
M. Lazewska ◽  
Z. Tabarowski ◽  
Z. Dabrowski

The effect of small doses of ethylene glycol monomethyl ether (EGMME) on the activity of acetylcholinesterase (ACHE) in erythrocytes and whole blood as well as on the Δ-aminolevulinic acid dehydratase (ALA-D) in blood and bone marrow was studied in Wistar rats. Significant reduction in the activity of both enzymes was noted three days after ip administration of 200 mg/kg b.w. EGMME whereas seven days later the activity of both enzymes returned to the control levels. Activity of ALA-D in blood appeared to be most sensitive to EGMME, and reacted even to the lowest dose, which did not significantly alter activity of ACHE or ALA-D in bone marrow. Haematological parameters in all treated groups remained unaltered.


2013 ◽  
Vol 27 (9) ◽  
pp. 5215-5221 ◽  
Author(s):  
Fenglan Fan ◽  
Lihua Jia ◽  
Xiangfeng Guo ◽  
Xiaopeng Lu ◽  
Juan Chen

Sign in / Sign up

Export Citation Format

Share Document