Perioperative HDR Brachytherapy for Reirradiation in Head and Neck Recurrences: Single-institution Experience and Systematic Review

2017 ◽  
Vol 103 (6) ◽  
pp. 516-524 ◽  
Author(s):  
Luca Tagliaferri ◽  
Francesco Bussu ◽  
Bruno Fionda ◽  
Francesco Catucci ◽  
Mario Rigante ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
High Dose Rate ◽  
Cochrane Library ◽  
High Dose ◽  
Tumor Bed ◽  
The Cochrane Library ◽  
Recurrent Head

Aim The aim of our study was to evaluate the outcomes of patients reirradiated with high-dose-rate (HDR) intensity-modulated brachytherapy (IMBT) for recurrent head and neck cancer and to perform a systematic review of the literature. Materials and Methods Patients treated with prior radiation doses >65 Gy were considered. After resection of macroscopic disease, catheters were fixed to the tumor bed. The total dose was 30 Gy in 12 fractions of 2.5 Gy twice daily for 5 days a week. A systematic literature search was conducted through several electronic databases including Medline/PubMed, Scopus, Embase and the Cochrane library. Results Seventeen patients were included; median overall survival was 19 months with a median local control interval of 15 months. Median follow-up was 36 months. Seven papers were considered for the review. Conclusions IMBT could play an important role in the retreatment of recurrent head and neck cancer.

High Dose Rate Intraoperative Radiotherapy for Recurrent Head and Neck Cancer

2007 ◽  
Vol 69 (3) ◽  
pp. S451
Author(s):  
K. Chan ◽  
D. Perry ◽  
S.L. Wolden ◽  
M.J. Zelefsky ◽  
J. Chiu ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
Intraoperative Radiotherapy ◽  
High Dose Rate ◽  
High Dose ◽  
Recurrent Head

High-dose-rate intraoperative brachytherapy and radical surgical resection in the management of recurrent head-and-neck cancer

Brachytherapy ◽  
2013 ◽  
Vol 12 (3) ◽  
pp. 228-234 ◽  
Author(s):  
Sewit Teckie ◽  
L. Matthew Scala ◽  
Felix Ho ◽  
Suzanne Wolden ◽  
Johnny Chiu ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Surgical Resection ◽  
Neck Cancer ◽  
High Dose Rate ◽  
High Dose ◽  
Radical Surgical Resection ◽  
Recurrent Head

Intraoperative high-dose-rate radiotherapy in the management of locoregionally recurrent head and neck cancer

Head & Neck ◽  
2013 ◽  
Vol 35 (4) ◽  
pp. 485-492 ◽  
Author(s):  
L. Matthew Scala ◽  
Kenneth Hu ◽  
Mark L. Urken ◽  
Adam S. Jacobson ◽  
Mark S. Persky ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
High Dose Rate ◽  
High Dose ◽  
Recurrent Head

scholarly journals Perioperative High-Dose-Rate Brachytherapy in Locally Advanced and Recurrent Head and Neck Cancer

Brachytherapy ◽  
2010 ◽  
Vol 9 ◽  
pp. S44
Author(s):  
Raquel Ciervide ◽  
Miren Gaztanaga ◽  
Inigo San Miguel ◽  
Maria Esperanza Rodriguez ◽  
Nestor Montesdeoca ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
Locally Advanced ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Recurrent Head

scholarly journals High-dose-rate interstitial brachytherapy in recurrent head and neck cancer: an effective salvage option

2018 ◽  
Vol 10 (5) ◽  
pp. 425-430 ◽  
Author(s):  
Rajendra Bhalavat ◽  
Vibhay Pareek ◽  
Manish Chandra ◽  
Lalitha Nellore ◽  
Karishma George ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
High Dose Rate ◽  
Interstitial Brachytherapy ◽  
High Dose ◽  
Recurrent Head

Salvage high-dose-rate (HDR) brachytherapy for recurrent head-and-neck cancer

2005 ◽  
Vol 62 (5) ◽  
pp. 1444-1450 ◽  
Author(s):  
Jaroslaw T. Hepel ◽  
A.M. Nisar Syed ◽  
Ajmel Puthawala ◽  
Anil Sharma ◽  
Paul Frankel
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
High Dose Rate ◽  
High Dose ◽  
Hdr Brachytherapy ◽  
Recurrent Head

High-Dose-Rate Intraoperative Radiation Therapy for Recurrent Head-and-Neck Cancer

2010 ◽  
Vol 76 (4) ◽  
pp. 1140-1146 ◽  
Author(s):  
David J. Perry ◽  
Kelvin Chan ◽  
Suzanne Wolden ◽  
Michael J. Zelefsky ◽  
Johnny Chiu ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Dose Rate ◽  
Neck Cancer ◽  
High Dose Rate ◽  
Intraoperative Radiation Therapy ◽  
High Dose ◽  
Intraoperative Radiation ◽  
Recurrent Head

Impact of Time to Diagnosis and Treatment in Head and Neck Cancer: A Systematic Review

2020 ◽  
Vol 162 (4) ◽  
pp. 446-457 ◽  
Author(s):  
Henrieke W. Schutte ◽  
Floris Heutink ◽  
David J. Wellenstein ◽  
Guido B. van den Broek ◽  
Frank J. A. van den Hoogen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Laryngeal Cancer ◽  
Neck Cancer ◽  
Functional Outcomes ◽  
Cochrane Library ◽  
Symptomatic Disease ◽  
Patient Reported ◽  
Time To Diagnosis

Objective An increased interval between symptomatic disease and treatment may negatively influence oncologic and/or functional outcomes in head and neck cancer (HNC). This systematic review aims to provide insight into the effects of time to treatment intervals on oncologic and functional outcomes in oral cavity, pharyngeal, and laryngeal cancer. Data Sources PubMed, EMBASE, and Cochrane library were searched. Review Methods All studies on delay or time to diagnosis or treatment in oral, pharyngeal, and laryngeal cancer were included. Quality assessment was performed with an adjusted version of the Newcastle-Ottawa scale. Outcomes of interest were tumor volume, stage, recurrence, survival, patient-reported outcome measures (PROMs), toxicity, and functionality after treatment. Results A total of 51 studies were included. Current literature on the influence of delay in HNC is inconsistent but indicates higher stage and worse survival with longer delay. The effects on PROMs, toxicity, and functional outcome after treatment have not been investigated. The inconsistencies in outcomes were most likely caused by factors such as heterogeneity in study design, differences in the definitions of delay, bias of results, and incomplete adjustment for confounding factors in the included studies. Conclusion Irrespective of the level of evidence, the unfavorable effects of delay on oncologic, functional, and psychosocial outcomes are undisputed. Timely treatment while maintaining high-quality diagnostic procedures and decision making reflects good clinical practice in our opinion. This review will pose practical and logistic challenges that will have to be overcome.

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