Effects of ondansetron on portal hemodynamics in liver cirrhosis

2000 ◽  
Vol 38 (09) ◽  
pp. 436-440
Author(s):  
M. Tripkovic ◽  
F. Kozjek ◽  
I. Krizman ◽  
J. Jereb ◽  
I. Francetic ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hemodynamics

Partial splenic embolization in patients with liver cirrhosis and hepatocellular carcinoma: Effects on portal hemodynamics

1994 ◽  
Vol 1 (2) ◽  
pp. 172-175 ◽  
Author(s):  
Kazuhiro Yamashiro ◽  
Mitsuhiro Mukaiya ◽  
Hiromichi Kimura ◽  
Tadashi Katsuramaki ◽  
Kazuaki Sasaki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Portal Hemodynamics ◽  
Splenic Embolization

scholarly journals Portal Hemodynamics and Portal Hypertensive Gastropathy in Liver Cirrhosis

1995 ◽  
Vol 46 (0) ◽  
pp. 136-137
Author(s):  
Toshiyuki Nakajima ◽  
Susumu Arai ◽  
Taiki Iwahori ◽  
Kenji Fujimori ◽  
Hiroshi Ohkune ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertensive Gastropathy ◽  
Portal Hemodynamics

scholarly journals Does Atorvastatin has Adding Effect to Propranolol in Control of Portal ‎Hemodynamics in Patients with Liver Cirrhosis

2022 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Mohammed Hussien Ahmed ◽  
Mona Talaat ◽  
Hebat Allah Abdel Maksoud Ahmed ◽  
Aya Mahros
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hemodynamics

Insulin reverses major portal hypertension-related derangements in rats with liver cirrhosis and diabetes

2018 ◽  
Vol 132 (22) ◽  
pp. 2391-2405
Author(s):  
I-Fang Hsin ◽  
Hui-Chun Huang ◽  
Ching-Chih Chang ◽  
Shao-Jung Hsu ◽  
Fa-Yauh Lee ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Liver Perfusion ◽  
Diabetic Rats ◽  
Vascular Density ◽  
Diabetic Patients ◽  
Common Bile Duct Ligation ◽  
Portal Hemodynamics ◽  
Duct Ligation ◽  
Protein Expressions ◽  
Portosystemic Collaterals

Liver cirrhosis is accompanied by increased intrahepatic resistance and angiogenesis-related portosystemic collaterals formation. Diabetic patients suffer from abnormal vasoresponsiveness and angiogenesis that can be ameliorated by glucose control. However, the relevant presentation is not clear in those with cirrhosis and diabetes, in whom insulin is the treatment of choice. Liver cirrhosis was induced in Sprague–Dawley rats with common bile duct ligation (BDL) and sham rats were used as controls. Streptozotocin 60 mg/kg (STZ, i.p., to induce diabetes) or vehicle was injected. The rats received BDL and STZ injections were injected with insulin or vehicle. On the 29th day after the procedure, the groups were surveyed for (1) systemic and portal hemodynamics; (2) mesenteric vascular density; (3) severity of portosystemic collaterals; (4) hepatic resistance using in situ liver perfusion; (5) histology survey of mesentery and liver; and (6) mesentery angiogenesis- and liver fibrogenesis-related protein expressions. Compared with the cirrhotic rats, the cirrhotic diabetic rats had lower body weight, cardiac output, superior mesenteric arterial (SMA) resistance and portal venous (PV) resistance, and higher SMA and PV flow, which were mostly reversed by insulin. The cirrhotic diabetic rats also had increased mesenteric vascular density, and enhanced pERK, pAkt, VEGF, VEGFR2 protein expressions that were reversed by insulin. Insulin decreased the degree of shunting in the diabetic cirrhotic rats. Hepatic perfusion pressure and severity of liver fibrosis were not significantly influenced by diabetes and insulin treatment in the cirrhotic rats. In conclusion, diabetes aggravated hemodynamic derangements, mesenteric angiogenesis and collaterals in the cirrhotic rats, which were mostly ameliorated by insulin. Further clinical investigations are warranted.

NO as an Indicator of Portal Hemodynamics and the Role of iNOS in Increased NO Production in CCl4-Induced Liver Cirrhosis

1997 ◽  
Vol 70 (2) ◽  
pp. 124-133 ◽  
Author(s):  
Masaki Mizumoto ◽  
Shigeki Arii ◽  
Masaharu Furutani ◽  
Toshio Nakamura ◽  
Shunnichi Ishigami ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
No Production ◽  
Portal Hemodynamics

scholarly journals Quantitative analysis of the portal hemodynamics in a case of liver cirrhosis showing hepatofugal flow in the portal trunk.

Kanzo ◽  
1987 ◽  
Vol 28 (4) ◽  
pp. 483-488 ◽  
Author(s):  
Toshihiko KAWASAKI ◽  
Fuminori MORIYASU ◽  
Osamu NISHIDA ◽  
Nobuyuki BAN ◽  
Takefumi NAKAMURA ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Quantitative Analysis ◽  
Portal Hemodynamics ◽  
Portal Trunk ◽  
Hepatofugal Flow

scholarly journals Comparison of portal hemodynamics between idiopathic portal hypertension and liver cirrhosis.

Kanzo ◽  
1985 ◽  
Vol 26 (12) ◽  
pp. 1625-1629
Author(s):  
Masayuki SAITO ◽  
Kunihiko OHNISHI ◽  
Hidetaka TERABAYASHI ◽  
Nobuyoshi CHIN ◽  
Shinichi SATO ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Idiopathic Portal Hypertension ◽  
Portal Hemodynamics

Relationship among gastric motility, autonomic activity, and portal hemodynamics in patients with liver cirrhosis

2001 ◽  
Vol 16 (6) ◽  
pp. 647-659 ◽  
Author(s):  
Hitoshi Miyajima ◽  
Masahiro Nomura ◽  
Naoki Muguruma ◽  
Toshiya Okahisa ◽  
Hiroshi Shibata ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Gastric Motility ◽  
Autonomic Activity ◽  
Portal Hemodynamics

Changes in portal hemodynamics after TIPS in liver cirrhosis and portal hypertension

2013 ◽  
Vol 48 (5) ◽  
pp. 570-576 ◽  
Author(s):  
Muna Palikhe ◽  
Hui Xue ◽  
Rajiv K. Jha ◽  
Ying Chao Li ◽  
Jia Yuan ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Portal Hemodynamics
Sign in / Sign up

Export Citation Format

Share Document