Partial splenic embolization in patients with liver cirrhosis and hepatocellular carcinoma: Effects on portal hemodynamics

1994 ◽  
Vol 1 (2) ◽  
pp. 172-175 ◽  
Author(s):  
Kazuhiro Yamashiro ◽  
Mitsuhiro Mukaiya ◽  
Hiromichi Kimura ◽  
Tadashi Katsuramaki ◽  
Kazuaki Sasaki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Portal Hemodynamics ◽  
Splenic Embolization

scholarly journals Sustained viral response (SVR) in type C liver cirrhosis patients undergoing peginterferon α-2b/ribavirin combination therapy after partial splenic embolization

Kanzo ◽  
2011 ◽  
Vol 52 (1) ◽  
pp. 26-35
Author(s):  
Keisuke Shiina ◽  
Atsushi Naganuma ◽  
Tomofumi Takakusaki ◽  
Masashi Namikawa ◽  
Hiroki Tahara ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Combination Therapy ◽  
Sustained Viral Response ◽  
Partial Splenic Embolization ◽  
Viral Response ◽  
Splenic Embolization ◽  
Type C ◽  
Peginterferon Α

631 THE EFFECT OF PARTIAL SPLENIC EMBOLIZATION FOR THROMBOCYTOPENIA IN LIVER CIRRHOSIS PATIENTS

2012 ◽  
Vol 56 ◽  
pp. S250 ◽  
Author(s):  
B.I. Kim ◽  
Y.K. Cho ◽  
H.J. Kim ◽  
J.H. Park ◽  
D.I. Park ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Splenic Embolization

scholarly journals Partial Splenic Embolization with Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma Accompanied by Thrombocytopenia

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Yoshihiko Ooka ◽  
Tetsuhiro Chiba ◽  
Sadahisa Ogasawara ◽  
Tenyu Motoyama ◽  
Eiichiro Suzuki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Failure ◽  
Transarterial Chemoembolization ◽  
Systemic Chemotherapy ◽  
Serum Levels ◽  
Severe Thrombocytopenia ◽  
Partial Splenic Embolization ◽  
Long Term Effects ◽  
Platelet Counts ◽  
Splenic Embolization

Background. Thrombocytopenia often makes the introduction of systemic treatment difficult in patients with cirrhosis and hepatocellular carcinoma (HCC). We retrospectively evaluated the long-term effects of partial splenic embolization (PSE) with transarterial chemoembolization (TACE) in patients with HCC patients accompanied by thrombocytopenia.Patients and Methods. Twenty-one patients with HCC complicated by severe thrombocytopenia (platelet count, <5.0 × 104/mm3) were treated with PSE and TACE. Both the safety and platelet-increasing effect was evaluated in these patients.Results. Seventeen of 21 patients (81.0%) showed increased platelet counts to ≥5.0 × 104/mm3. Subsequently, 13 patients (61.9%) successfully received systemic chemotherapy. Platelet counts and serum levels of total bilirubin, as well as neutrophil counts, improved significantly one month after treatment. However, serum levels of albumin and hemoglobin decreased significantly one month after treatment. Severe adverse events, including acute liver failure and portal vein thrombus, were observed in two patients.Conclusion. PSE with selective TACE made it possible for patients with HCC and severe thrombocytopenia to receive systemic chemotherapy. Although PSE with TACE was safe and tolerable for most patients, the extent of PSE with TACE in a wide area of the liver may increase the risk for fatal liver failure.

Therapeutic benefits of partial splenic embolization for thrombocytopenia in hepatocellular carcinoma patients treated with radiofrequency ablation

2009 ◽  
Vol 39 (8) ◽  
pp. 772-778 ◽  
Author(s):  
Hisashi Hidaka ◽  
Shigehiro Kokubu ◽  
Takahide Nakazawa ◽  
Tsutomu Minamino ◽  
Juichi Takada ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Partial Splenic Embolization ◽  
Therapeutic Benefits ◽  
Splenic Embolization
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