scholarly journals A rare case of invasive mole with silent uterine perforation

2013 ◽  
pp. 109-110
Author(s):  
Sahaja Kittur ◽  
Venktesh Venktesh ◽  
Ramlingappa A.
Keyword(s):  
Rare Case ◽  
Uterine Perforation ◽  
Invasive Mole

scholarly journals Gestational trophoblastic neoplasia (invasive mole) following incomplete abortion- a rare case presenting with uterine perforation with gross hemoperitoneum: A case report

2017 ◽  
Vol 6 (4) ◽  
pp. 63-67
Author(s):  
G Neupane ◽  
S Acharya
Keyword(s):  
Rare Case ◽  
Single Agent ◽  
Emergency Laparotomy ◽  
Uterine Perforation ◽  
Gestational Trophoblastic Neoplasia ◽  
Vacuum Aspiration ◽  
Normal Limits ◽  
Incomplete Abortion ◽  
Beta Hcg ◽  
Invasive Mole

 Invasive mole is gestational trophoblastic neoplasia, characterized by aggressive invasion of the wall of the uterus by the trophoblastic cells. Here, we report a rare case of 17 years primigravida who presented with per vaginal bleeding and uterine perforation with gross hemoperitoneum about 1 month of manual vacuum aspiration of incomplete abortion. Resuscitation followed by emergency laparotomy with subsequent repair of uterine perforation was done. The patient received a total of 5 cycles of single agent chemotherapy (Methotrexate with leukovorin rescue). The beta hCG level became normal after 3 cycles of chemotherapy and further 2 cycles chemotherapy was administered. She was followed up for another 1 year in which her beta hCG levels were within normal limits. 

scholarly journals Choriocarcinoma with uterine rupture presenting as acute haemoperitoneum and shock

2017 ◽  
Vol 6 (3) ◽  
pp. 1141 ◽  
Author(s):  
Mamour Gueye ◽  
Mame Diarra Ndiaye Gueye ◽  
Ousmane Thiam ◽  
Youssou Toure ◽  
Mor Cisse ◽  
...  
Keyword(s):  
Young Woman ◽  
Uterine Rupture ◽  
Gestational Trophoblastic Disease ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Rare Neoplasm ◽  
Trophoblastic Disease ◽  
Intraperitoneal Bleeding ◽  
Invasive Mole

Choriocarcinoma is a rare neoplasm and a malignant form of gestational trophoblastic disease. Invasive mole may perforate uterus through the myometrium resulting in uterine perforation and intraperitoneal bleeding. But uterine perforation due to choriocarcinoma is rare. We present a case of a young woman who presented 1 year after uterine evacuation of a molar pregnancy with invasive choriocarcinoma complicated by a uterine rupture and haemoperitoneum.

scholarly journals A Rare Case of Intrauterine Adhesion Caused by Intrauterine Fallopian Tube Incarceration

2021 ◽  
pp. 64-67
Author(s):  
Yiran Liu ◽  
Yugang Chi
Keyword(s):  
Fallopian Tube ◽  
Rare Case ◽  
Early Recognition ◽  
Uterine Cavity ◽  
Uterine Perforation ◽  
Secondary Infertility ◽  
False Passage ◽  
Intrauterine Adhesion ◽  
Tubal Lumen ◽  
The Right

Hysteroscopy is widely used for the detection and treatment of intrauterine adhesion. Such technique, however, sometimes has limitations and even second damages. We report a rare case of severe intrauterine adhesion caused by uterine perforation with a fallopian tube incarceration. A 24-year-old woman underwent severe intrauterine adhesion and secondary infertility caused by fallopian tube incaceration into the uterine cavity after postpartum curettage. First hysteroscopy created a false passage through the previous uterine perforation, entered into the cavity of incarcerated fallopian tube, and led to iatrogenic hydrosalpinx. Secondary hysteroscopy combined with laparoscopy revealed a connection between the right tubal lumen and the uterine cavity by the false passage, released the adhesion, and reconstructed the uterine cavity. Early recognition of uterine perforation or tissue incarcerarion is significant in preventing further damage.

scholarly journals Uterine Perforation on Invasive Hydatidiform Mole during EMACO Treatment

2016 ◽  
Author(s):  
Bram Pradipta
Keyword(s):  
Hydatidiform Mole ◽  
Broad Ligament ◽  
Posterior Part ◽  
Exploratory Laparotomy ◽  
Recurrent Bleeding ◽  
Uterine Perforation ◽  
Long Term Treatment ◽  
History Of ◽  
Invasive Mole ◽  
The Right

Objective: Improving skill and knowledge to recognize and manage a rare case of uterine perforation on invasive hydatidiform mole. Method: Case report. Result: A 42 years old Indonesian woman, Parity 2 Abortus 2 with history of 2 c-sections and 2 curettage, came with chief complaint of recurrent vaginal bleeding since 4 months before admission. Patient had a history of previous curettage with indication of hydatidiform mole and recurrent bleeding with no histopathology results. On examination we found a vesicular mass with infiltration, destroying the right-front uterine corpus, size 8x6 cm with an internal echo mass. Chest x-ray showed multiple nodules in the lung. The patient, considered as low risk Gestational Trophoblastic Neoplasia patient with FIGO Score of 6, underwent chemotherapy with 2 series of methotrexate . Due to the non-declining level of -hCG, the regimen was added with EMACO. In the process of chemotherapy, the pa-tient’s-hCG declined but then she complained of major abdominal pain. Exploratory laparotomy was performed and we found a mass sized 5x5x5 cm on the right side of the uterus at the broad ligament with a rupture at the posterior part of the mass sized 0.5x0.5 cm. Upon incision of the uterus, we found a mass from the right side protruding to the isthmus of the uterus. Histopathology showed necrosis, blood and chorionic villi in myometrium corresponding to invasive mole. Patient was then given another 5 series of EMACO and her condition was unremarkable during the remaining course of treatment. Conclusion: Invasive mole treatment is determined based on the risk factors. Uterine perforation still occurred in this case regardless of the decreasing hCG level during EMACO treatment. It emphasizes the importance of clinical examination as chemotherapy responsiveness. Long-term treatment can have a good prognosis but good collaboration between the gynecologist and the patient is essential. [Indones J Obstet Gynecol 2014; 3: 162-165] Keywords: EMACO, invasive mole, perforation

scholarly journals A rare, ectopic (intravesical) location of a missing intrauterine contraceptive device, a case report

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Adewale Erioluwa Oguntoyinbo ◽  
Ifetoluwani Oluwadunsin Oguntoyinbo ◽  
Oluwabunmi Esther Oguntoyinbo ◽  
Issa Aremu Babatunde
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Intrauterine Contraceptive Device ◽  
Uterine Perforation ◽  
Contraceptive Device ◽  
Normal Position ◽  
Intrauterine Contraceptive ◽  
Uterine Fundus

Ectopic location of Intrauterine Contraceptive Device (IUCD) or its migration from the normal position in the uterine fundus is a frequently encountered complication. It varies from uterine expulsion to displacement into the endometrial canal to uterine perforation or intravesical migration, which is an extremely rare case. Ultrasonography was used in the diagnoses of this reported case of an ectopic intravesical IUCD.

Gestational trophoblastic disease in Nepalese women managed in B. P. Koirala Memorial Cancer Hospital

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e16570-e16570
Author(s):  
J. Pariyar
Keyword(s):  
Brain Metastasis ◽  
Ethnic Group ◽  
Gestational Trophoblastic Disease ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Trophoblastic Disease ◽  
Cancer Hospital ◽  
Invasive Mole ◽  
Disseminated Disease

e16570 Background: Gestational trophoblastic disease (GTD) is potentially curable disease. Its incidence varies in different countries with high incidence reported in Japan (2/1000 pregnancies) and Mexico (2.5/1000 pregnancies). No studies have been reported regarding epidemiology, management and outcome of GTD in Nepal. Methods: The study was a descriptive case series. Case records of GTD patients attending B.P. Koirala Memorial Cancer Hospital, Nepal from 2001 to 2007 were analyzed. The main outcomes were measured in terms of duration, antecedent pregnancy, investigations, treatment and follow-up. Results: A total of 45 cases of gestational trophoblastic disease (GTD) were received from 26 districts of Nepal. The age of the patients ranged from 16 to 50 years with a mean age of 29.1 years (SD 9.4 years). Out of 45 cases 19 (43%) were of Tibeto-Burmese ethnic group and 15 (33%) belonged to Indo-Aryan ethnic group. There were 17 cases (37.8%) of hydatidiform mole, 6 were invasive mole (13.35%), 4 of persistent gestational trophoblastic tumour (8.8%) and 22 patients (48.8%) of choriocarcinoma. In 7 cases (15.5%) molar pregnancy had occurred in the first conception, another 7 cases (15.5%) had previous molar pregnancy and in 16 (35.5%) cases GTD had occurred following abortion. The most common presenting symptom was vaginal bleeding and 26 (57.8%) patients had anaemia. Theca Leuteal cyst was present in 11 (24.5%), 17 (37.8%) cases had lung metastasis, 4 (8.9%) had brain metastasis and another 4 (8.9%) had disseminated disease detecteted radiologically. Among the 45 cases 6 (13.3%) were treated with suction evacuation only; 9 (20%) underwent hysterectomy for uterine perforation, excessive hemorrhage and invasive mole. 28 (62.2%) cases underwent adjuvant chemotherapy among which 12 (26.6%) received single agent chemotherapy and 15 (33.3%) received EMA-CO regimen. Brain irradiation was required in a case with brain metastasis. Five (11.1%) cases with disseminated disease and high WHO risk score left the hospital against medical advice. There were 3 (6.7%) mortalities. 37 (82.1%) cases are in remission and follow-up. Conclusions: Early diagnosis of disease and proper management strongly influences the outcome of GTD. Even in disseminated state GTD can be cured. No significant financial relationships to disclose.

scholarly journals Recurrent hydatidiform mole transformed into invasive mole with co-morbid depression- a rare case report

2017 ◽  
Vol 6 (7) ◽  
pp. 3197
Author(s):  
Nisha Bhagat ◽  
Rajnish Raj
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Hydatidiform Mole ◽  
Gestational Trophoblastic Disease ◽  
Placental Site Trophoblastic Tumor ◽  
Trophoblastic Disease ◽  
Placental Site ◽  
Rare Case Report ◽  
Invasive Mole ◽  
Methotrexate Chemotherapy

The gestational trophoblastic disease is a group of interrelated lesions that arise from abnormal proliferation of placental trophoblast. It comprises of hydatidiform mole (partial or complete), invasive mole, placental site trophoblastic tumor and choriocarcinoma. The occurrence of hydatidiform mole in more than two conceptions is known as recurrent hydatidiform mole. Although, its incidence is less than 2% but it may progress to invasive mole or choriocarcinoma. The case of 26-year old female is reported; she had five consecutive molar pregnancies and the sixth one developed into invasive mole with co-morbid depression that was managed by methotrexate chemotherapy, antidepressant and psychotherapy. 

scholarly journals A case of invasive mole presenting as perforation uterus and massive haemoperitonium

2016 ◽  
Author(s):  
Arti Sharma
Keyword(s):  
Acute Abdominal Pain ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Gestational Trophoblastic Neoplasia ◽  
Distinct Subgroup ◽  
Rare Tumours ◽  
Packed Cell Transfusion ◽  
History Of ◽  
Invasive Mole ◽  
Uterine Fundus

Gestational trophoblastic neoplasia (GTN) are rare tumours that constitute less than 1% of all gynecological malignancies. Invasive mole is a distinct subgroup of GTN, which follows approximately 10-15% of complete hydatiform moles. This is a case of invasive mole presenting as uterine perforation and massive haemoperitonium. The 35 year old parous woman presented with severe pallor, acute abdominal pain and hemoperitonium. She gave history of evacuation of a molar pregnancy four month back. Her serum B-HCG was elevated (80,000 IU/ml). Laprotomy revealed perforation through the uterine fundus with purple discolouration and grapes like vesicle with massive haemoperitonium. Patient was managed by hysterectomy and packed cell transfusion was given. Postoperative followup with B-HCG levels was done and chemotherapy (methotrexate and folinic acid) was given.

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