Methylene Blue Administration Mimics an Oxygenator Failure during Cardiopulmonary Bypass

10.5580/1a8e ◽  
2009 ◽  
Vol 13 (1) ◽  
Keyword(s):  
Methylene Blue ◽  
Cardiopulmonary Bypass

Methylene blue does not neutralize heparin after cardiopulmonary bypass

1996 ◽  
Vol 10 (4) ◽  
pp. 474-476 ◽  
Author(s):  
Samuel Metz ◽  
Jan C. Horrow ◽  
Inder P. Goel ◽  
M.L.R. Kuretu ◽  
Collette Bellwoar
Keyword(s):  
Methylene Blue ◽  
Cardiopulmonary Bypass

scholarly journals The Use of Methylene Blue during Liver Transplantation for Vasoplegia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Paul Harding ◽  
Thomas Nicholas ◽  
Cale Kassel
Keyword(s):  
Septic Shock ◽  
Methylene Blue ◽  
Liver Transplantation ◽  
Cardiopulmonary Bypass ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Treatment Option ◽  
Case Reports ◽  
Refractory Hypotension

The use of methylene blue for vasoplegia in cardiac cases with cardiopulmonary bypass, septic shock, and acute liver failure is well documented. Use of MB for liver transplantation has been largely limited to case reports. We describe three separate liver transplantation patients with significant hypotension following reperfusion. Administration of methylene blue to each patient resulted in a significant decrease in vasopressor medication and two patients weaned completely. We argue that the use of MB should be considered as a treatment option for refractory hypotension.

scholarly journals Methylene Blue for Vasoplegic Syndrome

2017 ◽  
Vol 20 (5) ◽  
pp. 234 ◽  
Author(s):  
Alexander T. Booth ◽  
Patrick D. Melmer ◽  
Benjamin Tribble ◽  
J. Hunter Mehaffey ◽  
Curt Tribble
Keyword(s):  
Methylene Blue ◽  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Side Effects ◽  
Vasodilatory Shock ◽  
Prospective Data ◽  
Dosing Strategies ◽  
High Doses ◽  
Vasoactive Medications ◽  
Vasoplegic Syndrome

Vasoplegic syndrome is a form of vasodilatory shock that occurs frequently in patients who undergo cardiac surgery requiring cardiopulmonary bypass (CBP). Treatment often demands high doses of vasopressors over sustained periods for hypotension that can be refractory to standard vasoactive medications. Furthermore, the development of vasoplegia greatly contributes to morbidity and mortality following cardiac surgery. Methylene blue (MB) has become a popular therapy for cardiac vasoplegia despite a paucity of prospective data to direct its use. Therefore, the aim of this study was to review available data regarding mechanisms, dosing strategies, and side effects of MB, with a focus on its applications for vasoplegia in cardiac surgery.

Methylene Blue for Vasoplegia When on Cardiopulmonary Bypass During Double-Lung Transplantation

2015 ◽  
Vol 5 (8) ◽  
pp. 127-130 ◽  
Author(s):  
Michelle Carley ◽  
Jacob Schaff ◽  
Terrance Lai ◽  
Jeremy Poppers
Keyword(s):  
Methylene Blue ◽  
Cardiopulmonary Bypass ◽  
Lung Transplantation

scholarly journals Methylene blue: the drug of choice for catecholamine-refractory vasoplegia after cardiopulmonary bypass

2003 ◽  
Vol 125 (6) ◽  
pp. 1426-1431 ◽  
Author(s):  
Rainer G Leyh ◽  
Theo Kofidis ◽  
Martin Strüber ◽  
Stefan Fischer ◽  
Karsten Knobloch ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Cardiopulmonary Bypass ◽  
Drug Of Choice
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