scholarly journals Cone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls

2016 ◽  
Vol 46 (1) ◽  
pp. 9 ◽  
Author(s):  
Allison Buchanan ◽  
Ruben Cohen ◽  
Stephen Looney ◽  
Sajitha Kalathingal ◽  
Scott De Rossi
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cone Beam Ct ◽  
Cone Beam ◽  
Obstructive Sleep ◽  
Ct Analysis ◽  
Normal Controls

scholarly journals Measurement of pharyngeal segments in Obstructive Sleep Apnea

2018 ◽  
Vol 21 (1) ◽  
pp. 64
Author(s):  
Marcos Marques Rodrigues ◽  
Lucas Borin Moura ◽  
Ariane De Souza Oliveira ◽  
Marisa Aparecida Cabrini Gabrielli ◽  
Valfrido Antonio Pereira Filho ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cone Beam Ct ◽  
Sleep Apnea Syndrome ◽  
Upper Airway ◽  
Cone Beam ◽  
Obstructive Sleep ◽  
Intimate Relation ◽  
The Mean ◽  
Cephalometric Measurements

<p><strong>Objective</strong>: Obstructive Sleep Apnea (OSA) occurs by recurrent collapse of the upper airway during sleep. It results in complete (apnea) or partial (hypopnea) reduction of airflow and has intimate relation with the upper airway anatomy. Cephalometric analysis has been used to quantify airway dimensions. The aim of this study is evaluate the correlation between the anteroposterior dimension of the upper airway and the severity of obstructive sleep apnea. <strong>Material and Methods</strong>: A retrospective analysis was performed reviewing polysomnographic data (AHI) and anteroposterior cephalometric measurements of pharynx subregions: nasopharynx, oropharynx, hypopharynx. <strong>Results</strong>: The sample consisted of 30 patients. The mean body mass index was 29.60 kg/m<sup>2</sup> and the average age was 46.8 years. Nine patients presented severe OSA, seven had moderate OSA , seven had mild OSA, and seven were healthy.  The Pearson's correlation index between the anteroposterior dimension of the nasopharynx, oropharynx and hypopharynx and AHI was respectively -0.128 (p=0.517), -0.272 (p=0.162) and -0.129 (p=0.513).<strong> Conclusion: </strong>The correlation between anteroposterior linear dimension of the airway and OSA severity, assessed by AHI, was not positive. As an isolated parameter it did not correlate to the severity of the obstrucive sleep apnea syndrome and should be evaluated in conjunction with other factors.</p><p><strong> </strong></p><p><strong>Keywords</strong></p><p>Upper Airway; Obstructive sleep apnea; Cone beam CT.</p>

scholarly journals Friedman tongue position and cone beam computed tomography in patients with obstructive sleep apnea

2017 ◽  
Vol 2 (5) ◽  
pp. 320-324 ◽  
Author(s):  
Rebecca Harvey ◽  
Louise O'Brien ◽  
Sharon Aronovich ◽  
Anita Shelgikar ◽  
Paul Hoff ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cone Beam Computed Tomography ◽  
Cone Beam ◽  
Obstructive Sleep ◽  
Tongue Position

Digital fluoroscopy before and after laser uvulopalatopharyngoplasty in obstructive sleep apnea

1997 ◽  
Vol 38 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Y. Tsushima ◽  
J. Antila ◽  
E. Laurikainen ◽  
E. Svedström ◽  
O. Polo ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Upper Airway ◽  
Poor Responders ◽  
Dynamic Changes ◽  
Digital Fluoroscopy ◽  
Obstructive Sleep ◽  
Before And After ◽  
Cephalometric Measurements ◽  
Normal Controls

Purpose: to study the changes in pharyngeal behavior after laser uvulopalatopharyngoplasty (LUPPP). Material and Methods: the dynamic changes in the upper airway size were evaluated with digital fluoroscopy in 24 patients with obstructive sleep apnea (OSA) before and after LUPPP and in 16 normal controls, while they were awake and breathing normally. Cephalometric measurements were also made. the patients were classified into the categories of good and poor responders by means of a static-charge-sensitive bed. Results: Following LUPPP, collapsibility at the velopharyngeal level was within the normal range in 15 of 17 good responders, but only in 2 of 7 poor responders (p=0.0086). the minimum airway size at the same level showed a similar trend. in 3 of 7 poor responders the hyoid bone was positioned more caudally than in the good responders (p=0.017). Conclusion: Digital fluoroscopy provides information on the change in upper airway behavior after LUPPP.

scholarly journals Alternations of Circadian Clock Genes Expression and Oscillation in Obstructive Sleep Apnea

2019 ◽  
Vol 8 (10) ◽  
pp. 1634 ◽  
Author(s):  
Yang ◽  
Lin ◽  
Lin ◽  
Lin ◽  
Chen ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Circadian Clock ◽  
Clock Genes ◽  
Expression Patterns ◽  
Binary Logistic Regression Analysis ◽  
Chain Reactions ◽  
Obstructive Sleep ◽  
Circadian Clock Genes ◽  
Normal Controls

Circadian misalignment plays an important role in disease processes and can affect disease severity, treatment outcomes, and even survivorship. In this study, we aim to investigate whether expression and daily oscillation patterns of core circadian clock genes were disturbed in patients with obstructive sleep apnea/hypopnea (OSA) syndrome. We performed real-time quantitative reverse transcriptase-polymerase chain reactions to examine the expression of the nine core circadian clock genes in leukocytes of peripheral blood collected at 12 AM, 6 AM, 12 PM, and 6 PM from 133 patients with OSA and 11 normal controls. Daily expression patterns of the nine circadian clock genes were observed in normal controls, but three of these genes (BMAL1, CLOCK, CRY2) were disrupted in patients with OSA. The expressions of eight circadian clock genes (except PER1) at midnight were significantly downregulated in patients with severe OSA. Binary logistic regression analysis selected CRY1 and PER3 as independent factors for severe OSA and showed that the combined expressions of CRY1 and PER3 enhanced the capability of predicting severe OSA (Odds ratio, 5.800; 95% CI, 1.978 to 17.004; p = 0.001). Our results show that combined expressions of CRY1 and PER3 at midnight could be a potential predictor for severe OSA.

Evaluation of Upper Airway in Children with Obstructive Sleep Apnea Using Cone‐Beam Computed Tomography

2020 ◽  
Author(s):  
Wei‐Chung Hsu ◽  
Kun‐Tai Kang ◽  
Chung‐Chen Jane Yao ◽  
Chen‐Han Chou ◽  
Wen‐Chin Weng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cone Beam Computed Tomography ◽  
Upper Airway ◽  
Cone Beam ◽  
Obstructive Sleep
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